Browsing Institutt for klinisk og molekylær medisin by Subject "VDP::Medisinsk genetikk: 714"
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Low expression levels of ATM may substitute for CHEK2/TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer
(Journal article; Peer reviewed, 2012)Introduction Mutations affecting p53 or its upstream activator Chk2 are associated with resistance to DNA-damaging chemotherapy in breast cancer. ATM (Ataxia Telangiectasia Mutated protein) is the key activator of p53 ... -
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
(Journal article; Peer reviewed, 2023)