Blar i Institutt for klinisk og molekylær medisin på tidsskrift "Molecular Cancer Research"

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    • EMT-derived alterations in glutamine metabolism sensitize mesenchymal breast cells to mTOR inhibition 

      Karvelsson, Sigurdur; Sigurdsson, Arnar; Seip, Kotryna; Grinde, Maria Tunset; Wang, Qiong; Johanssson, Freyr; Mælandsmo, Gunhild Mari; Moestue, Siver Andreas; Rolfsson, Ottar; Halldórsson, Skarphédinn (Peer reviewed; Journal article, 2021)
      Epithelial-to-mesenchymal transition (EMT) is a fundamental developmental process with strong implications in cancer progression. Understanding the metabolic alterations associated with EMT may open new avenues of treatment ...

    • Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3 

      Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Holien, Toril; Sponaas, Anne-Marit; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Børset, Magne (Journal article; Peer reviewed, 2016)
      Phosphatase of regenerating liver-3 (PTP4A3/PRL-3) is a dual-specificity phosphatase that is upregulated in various types of cancers and is related to poor prognosis and aggressive tumor behavior. The expression level of ...