Blar i Institutt for klinisk og molekylær medisin på forfatter "Wagoner, Jessica"
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Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2
Wagoner, Jessica; Herring, Shawn; Hsiang, Tien-Ying; Ianevski, Aleksandr; Biering, Scott B.; Xu, Shuang; Hoffmann, Markus; Pöhlmann, Stefan; Gale, Michael; Aittokallio, Tero Antero; Schiffer, Joshua T.; White, Judith M.; Polyaka, Stephen J. (Peer reviewed; Journal article, 2022)Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents did not completely prevent severe illness and are associated with ... -
Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2–host protein–protein interaction network
Vandana, Vandana; Aittokallio, Tero Antero; Frigessi, Arnoldo; Athanasiadis, Paschalis; Wagoner, Jessica; Hartigh, Andreas B Den; Sidorova, Julia; Ianevski, Aleksandr; Fink, Susan L.; White, Judith M.; Polyak, Stephen J. (Peer reviewed; Journal article, 2022)The ongoing coronavirus disease 2019 (COVID-19) pandemic has highlighted the need to better understand virus–host interactions. We developed a network-based method that expands the severe acute respiratory syndrome ...