Blar i Institutt for klinisk og molekylær medisin på forfatter "Vale, Luke D."
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Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review
Hislop, Jenni; Adewuyi, Temitope E.; Vale, Luke D.; Harrild, Kirsten; Fraser, Cynthia; Gurung, Tara; Altman, Douglas G.; Briggs, Andrew H.; Fayers, Peter; Ramsay, Craig R.; Norrie, John D.; Harvey, Ian M.; Buckley, Brian; Cook, Jonathan A. (Journal article; Peer reviewed, 2014)Background Randomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified ... -
Specifying the target difference in the primary outcome for a randomised controlled trial: Guidance for researchers
Cook, Jonathan A.; Hislop, Jenni; Altman, Douglas G.; Fayers, Peter; Briggs, Andrew H.; Ramsay, Craig R.; Norrie, John D.; Harvey, Ian M.; Buckley, Brian; Fergusson, D; Ford, Ian; Vale, Luke D. (Journal article; Peer reviewed, 2015)Background Central to the design of a randomised controlled trial is the calculation of the number of participants needed. This is typically achieved by specifying a target difference and calculating the corresponding ...