• Alpha-tocopherol and MRI outcomes in multiple sclerosis - association and prediction 

      Løken-Amsrud, Kristin Ingeleiv; Myhr, Kjell-Morten; Bakke, Søren Jacob; Beiske, Antonie Giæver; Bjerve, Kristian S; Bjørnarå, Bård T.; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Saltyte Benth, Jurate; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve (Journal article; Peer reviewed, 2013)
      Objective: Alpha-tocopherol is the main vitamin E compound in humans, and has important antioxidative and immunomodulatory properties. The aim of this study was to study alpha-tocopherol concentrations and their relationship ...
    • Cognitive Trajectories in Older Patients with Cancer Undergoing Radiotherapy—A Prospective Observational Study 

      Eriksen, Guro Falk; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Kirkevold, Øyvind; Bergh, Sverre; Hjelstuen, Anne Kristine; Rolfson, Darryl; Jordhøy, Marit Slaaen (Peer reviewed; Journal article, 2022)
      Cognitive function can be affected by cancer and/or its treatment, and older patients are at a particular risk. In a prospective observational study including patients ≥65 years referred for radiotherapy (RT), we aimed to ...
    • Complement activation is associated with poor outcome after out-of-hospital cardiac arrest 

      Chaban, Viktoriia; Nakstad, Espen R.; Stær-Jensen, Henrik; Schjalm, Camilla; Seljeflot, Ingebjørg; Vaage, Ingvar Jarle; Lundqvist, Christofer; Saltyte Benth, Jurate; Sunde, Kjetil; Mollnes, Tom Eirik; Andersen, Geir Øystein; Pischke, Soeren (Peer reviewed; Journal article, 2021)
      Background Cardiopulmonary resuscitation after cardiac arrest initiates a whole-body ischemia-reperfusion injury, which may activate the innate immune system, including the complement system. We hypothesized that complement ...
    • CT Derived Muscle Measures, Inflammation, and Frailty in a Cohort of Older Cancer Patients 

      Harneshaug, Magnus; Saltyte Benth, Jurate; Kirkhus, Lene; Grønberg, Bjørn Henning; Bergh, Sverre; Rostoft, Siri; Jordhøy, Marit Slaaen (Peer reviewed; Journal article, 2020)
      Background/Aim: Muscle loss, inflammation, and frailty are prevalent among older cancer patients. We aimed to evaluate whether inflammatory markers could identify muscle loss, and if muscle measures differed between frail ...
    • Edmonton Frail Scale predicts mortality in older patients with cancer undergoing radiotherapy-A prospective observational study 

      Røyset, Inga Marie; Eriksen, Guro Falk; Saltyte Benth, Jurate; Saltvedt, Ingvild Tina; Grønberg, Bjørn Henning; Rostoft, Siri; Kirkevold, Øyvind; Rolfson, Darryl; Jordhøy, Marit Slaaen (Peer reviewed; Journal article, 2023)
      Background: Several screening tools are developed to identify frailty in the increasing number of older patients with cancer. Edmonton Frail Scale (EFS) performs well in geriatric settings but is less studied in oncology. ...
    • Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons 

      Gaarden, Torfinn Lødøen; Engedal, Knut; Saltyte Benth, Jurate; Larsen, Marianne; Lorentzen, Bernhard; Mollnes, Tom Eirik; Bjølseth, Tor Magne; Castellheim, Albert (Journal article; Peer reviewed, 2018)
      Background The prevalence of major depression (MD) according to population studies is the same for old (65 years and older) and younger adults. In contrast, an elevated proportion of old MD patients are hospitalized ...
    • Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty 

      Kirkhus, Lene; Saltyte Benth, Jurate; Kristjansson, Siri Rostoft; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Harneshaug, Magnus; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2017)
      Background: Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ...
    • Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study 

      Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)
      About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ...
    • Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity 

      Holmøy, Trygve; Løken-Amsrud, Kristin Ingeleiv; Bakke, Jacob; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Saltyte Benth, Jurate; Torkildsen, Øivind; Wergeland, Stig; Myhr, Kjell-Morten; Michelsen, Annika; Aukrust, Pål; Ueland, Thor (Journal article; Peer reviewed, 2013)
      Background: Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore ...
    • Modifiable factors affecting older patients' quality of life and physical function during cancer treatment 

      Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ...
    • No association of tobacco use and disease activity in multiple sclerosis 

      Kvistad, Silje; Myhr, Kjell-Morten; Holmøy, Trygve; Saltyte Benth, Jurate; Løken-Amsrud, Kristin Ingeleiv; Wergeland, Stig; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Bakke, Søren Jacob; Torkildsen, Øivind (Journal article; Peer reviewed, 2016)
      Objective: To study whether tobacco use is associated with MRI and clinical disease activity in patients with multiple sclerosis (MS). Methods: Prospective cohort study of 87 patients with relapsing-remitting MS originally ...
    • Screening for frailty among older patients with cancer using blood biomarkers of inflammation 

      Harneshaug, Magnus; Kirkhus, Lene; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Bergh, Sverre; Whist, Jon Elling; Rostoft, Siri; Jordhøy, Marit Slaaen (Peer reviewed; Journal article, 2018)
      As frailty is associated with inflammation, biomarkers of inflammation may represent objective measures that could facilitate the identification of frailty. Glasgow prognostic score (GPS), combines C-reactive protein (CRP) ...