• SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19 

      Sahanic, Sabina; Hilbe, Richard; Dünser, Christina; Tymoszuk, Piotr; Löffler-Ragg, Judith; Rieder, Dietmar; Trajanoski, Zlatko; Krogsdam, Anne; Demetz, Egon; Yurchenko, Maria; Fischer, Christine; Schirmer, Michael; Theurl, Markus; Lener, Daniela; Hirsch, Jakob; Holfeld, Johannes; Gollmann-Tepeköylü, Can; Zinner, Carl P.; Tzankov, Alexandar; Zhang, Shen-Ying; Casanova, Jean-Laurent; Posch, Wilfried; Wilflingseder, Doris; Weiss, Guenter; Tancevski, Ivan (Peer reviewed; Journal article, 2023)
      Background Toll-like receptors (TLRs) play a pivotal role in the immunologic response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Exaggerated inflammatory response of innate immune cells, ...