Browsing Institutt for klinisk og molekylær medisin by Author "Qvigstad, Gunnar"
Now showing items 1-6 of 6
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Animal models to study the role of long-term hypergastrinemia in gastric carcinogenesis
Fossmark, Reidar; Qvigstad, Gunnar; Martinsen, Tom Christian; Hauso, Øyvind; Waldum, Helge (Journal article; Peer reviewed, 2011)Patients with chronic hypergastrinemia due to chronic atrophic gastritis or gastrinomas have an increased risk of developing gastric malignancy, and it has been questioned whether also patients with hypergastrinemia caused ... -
Do Gastric Signet Ring Cell Carcinomas and ECL‐Cell Neuroendocrine Tumours Have a Common Origin?
Fossmark, Reidar; Johannessen, Rune; Qvigstad, Gunnar; Mjønes, Patricia (Peer reviewed; Journal article, 2022)Gastric cancer is a heterogenous group of tumours, and a better understanding of the carcinogenesis and cellular origin of the various sub-types could affect prevention and future treatment. Gastric neuroendocrine tumours ... -
Expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma
Mjønes, Patricia; Nordrum, Ivar Skjåk; Qvigstad, Gunnar; Sørdal, Øystein Finset; Rian, Liselotte Linnea Mårtensson; Waldum, Helge (Journal article; Peer reviewed, 2017)The aim of the study was to investigate the expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma (CCRCC). We retrospectively reviewed the medical records and re-evaluated histopathological ... -
Gastric Cancers Missed at Upper Endoscopy in Central Norway 2007 to 2016—a Population-Based Study
Beck, Marianne; Bringeland, Erling A.; Qvigstad, Gunnar; Fossmark, Reidar (Peer reviewed; Journal article, 2021)Simple summary: Stomach cancer may be missed during upper endoscopy. We have examined how often this occurs and identified factors associated with missed cancers. Among 730 patients with gastric cancer, 67 (9.2%) were ... -
Genetic Rescue of the Highly Inbred Norwegian Lundehund
Melis, Claudia; Pertoldi, Cino; Ludington, William Basil; Beuchat, Carol; Qvigstad, Gunnar; Stronen, Astrid Vik (Journal article; Peer reviewed, 2022)Augmenting the genetic diversity of small, inbred populations by the introduction of new individuals is often termed “genetic rescue“. An example is the Norwegian Lundehund, a small spitz dog with inbreeding-related health ... -
The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival
Vange, Pål; Bruland, Torunn; Doseth, Berit; Fossmark, Reidar; Sousa, Mirta; Beisvag, Vidar; Sørdal, Øystein Finset; Qvigstad, Gunnar; Waldum, Helge; Sandvik, Arne Kristian; Bakke, Ingunn (Journal article; Peer reviewed, 2017)The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated ...