• The alternative complement pathway is dysregulated in patients with chronic heart failure 

      Shahini, Negar; Michelsen, Annika; Nilsson, Per; Ekholt, Karin; Gullestad, Lars; Broch, Kaspar; Dahl, Christen Peder; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Yndestad, Arne; Louwe, Maria Cornelia (Journal article; Peer reviewed, 2017)
      The complement system, an important arm of the innate immune system, is activated in heart failure (HF). We hypothesized that HF patients are characterized by an imbalance of alternative amplification loop components; ...
    • The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis 

      Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore; Espevik, Terje; Mollnes, Tom Eirik (Peer reviewed; Journal article, 2015)
      Despite recent medical advances, atherosclerosis is a global burden accounting for numerous deaths and hospital admissions. Immune-mediated inflammation is a major component of the atherosclerotic process, but earlier ...