Blar i Institutt for klinisk og molekylær medisin på tidsskrift "Genome Biology"
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A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment
(Peer reviewed; Journal article, 2023)Background Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant ... -
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
(Journal article; Peer reviewed, 2018)Background N 6 -methyladenosine (m6A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 ...