Blar i Institutt for klinisk og molekylær medisin på tidsskrift "BMC Genomics"
Viser treff 1-6 av 6
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Cell-type specificity of ChIP-predicted transcription factor binding sites
(Journal article; Peer reviewed, 2012)Background Context-dependent transcription factor (TF) binding is one reason for differences in gene expression patterns between different cellular states. Chromatin immunoprecipitation followed by high-throughput sequencing ... -
Chromatin states reveal functional associations for globally defined transcription start sites in four human cell lines
(Journal article; Peer reviewed, 2014)Background Deciphering the most common modes by which chromatin regulates transcription, and how this is related to cellular status and processes is an important task for improving our understanding of human cellular ... -
Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library.
(Journal article; Peer reviewed, 2017)BACKGROUND: Polysaccharides often are necessary components of bacterial biofilms and capsules. Production of these biopolymers constitutes a drain on key components in the central carbon metabolism, but so far little is ... -
Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection
(Journal article; Peer reviewed, 2014)Background Mycobacterium avium subsp. avium (Maa) and M. avium subsp. hominissuis (Mah) are environmental mycobacteria and significant opportunistic pathogens. Mycobacterium avium infections in humans and pigs are mainly ... -
Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits
(Journal article; Peer reviewed, 2014)Background Gene duplication and horizontal gene transfer are common processes in bacterial and archaeal genomes, and are generally assumed to result in either diversification or loss of the redundant gene copies. However, ... -
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis
(Journal article; Peer reviewed, 2013)Background How cells decipher the duration of an external signal into different transcriptional outcomes is poorly understood. The hormone gastrin can promote a variety of cellular responses including proliferation, ...