Browsing Institutt for klinisk og molekylær medisin by Journals "Antimicrobial Agents and Chemotherapy"
Now showing items 1-2 of 2
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A novel antimycobacterial compound acts as an intracellular iron chelator
(Journal article; Peer reviewed, 2015)Efficient iron acquisition is crucial for the pathogenesis of Mycobacterium tuberculosis. Mycobacterial iron uptake and metabolism are therefore attractive targets for antitubercular drug development. Resistance mutations ... -
Silenced vanA gene cluster on a transferable plasmid cause outbreak of vancomycin variable enterococci
(Journal article; Peer reviewed, 2016-05)We report an outbreak of vancomycin-variable vanA+ enterococci (VVE) able to escape phenotypic detection by current guidelines and demonstrate the molecular mechanisms for in vivo switching into vancomycin resistance and ...