Browsing Fakultet for medisin og helsevitenskap (MH) by Title

Now showing items 11723-11742 of 14995

    • The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes 

      Holtet Evensen, Line; Arnesen, Carl-Arne; Rosendaal, Frits Richard; Gabrielsen, Maiken Elvestad; Brumpton, Ben Michael; Hveem, Kristian; Hansen, John Bjarne; Brækkan, Sigrid Kufaas (Peer reviewed; Journal article, 2022)
      Background The proportion of venous thromboembolism (VTE) events that can be attributed to established prothrombotic genotypes has been scarcely investigated in the general population. We aimed to estimate the proportion ...

    • Risk profile, antithrombotic treatment and clinical outcomes of patients in Nordic countries with atrial fibrillation–results from the GARFIELD-AF registry 

      Pope, Marita K; Atar, Dan; Svilaas, Arne B; Hole, Torstein; Nielsen, Jørn Dalsgaard; Hintze, Ulrik; Crisby, Milita; Raatikainen, Pekka; Airaksinen, K.E. Juhani; Virdone, Saverio; Pieper, Karen; Kayani, Gloria; Le Heuzey, Jean-Yves; Steffel, Jan; Stepinska, Janina; Bassand, Jean-Pierre; Camm, A. John (Peer reviewed; Journal article, 2021)
      Aims The objective was to evaluate the clinical characteristics, management and two-year outcomes of patients with newly diagnosed non-valvular atrial fibrillation at risk for stroke in Nordic countries. Methods We ...

    • Risk scores for prediction of 30-day mortality after transcatheter aortic valve implantation: Results from a two-center study in Norway 

      Kjønås, Didrik; Dahle, Gro; Schirmer, Henrik; Malm, Siri; Eidet, Jo; Aaberge, Lars; Steigen, Terje; Aakhus, Svend; Busund, Rolf; Røsner, Assami (Journal article; Peer reviewed, 2021)
      Objectives Transcatheter aortic valve implantation (TAVI)-specific risk scores have been developed based on large registry studies. Our aim was to evaluate how both surgical and novel TAVI risk scores performed in predicting ...

    • Risk Stratification in Patients with Ischemic Stroke and Residual Cardiovascular Risk with Current Secondary Prevention 

      Gynnild, Mari Nordbø; Hageman, Steven HJ; Dorresteijn, Jannick AN; Spigset, Olav; Lydersen, Stian; Wethal, Torgeir; Saltvedt, Ingvild; Visseren, Frank LJ; Ellekjær, Hanne (Peer reviewed; Journal article, 2021)
      Purpose: Suboptimal secondary prevention in patients with stroke causes a remaining cardiovascular risk desirable to reduce. We have validated a prognostic model for secondary preventive settings and estimated future ...

    • Risk-taking behavior of adolescents and young adults born preterm 

      Alenius, Suvi; Kajantie, Eero Olavi; Sund, Reijo; Nurhonen, Markku; Haaramo, Peija; Näsänen-Gilmore, Pieta; Vääräsmäki, Marja; Lemola, Sakari; Räikkönen, Katri; Schnitzlein, Daniel D.; Wolke, Dieter; Gissler, Mika; Hovi, Petteri (Peer reviewed; Journal article, 2023)
      Objectives To study sexually transmitted Chlamydia trachomatis infections (STCTs), teenage pregnancies, and payment defaults in individuals born preterm as proxies for engaging in risk-taking behavior. Study design Our ...

    • Risks and benefits of brain tumor surgery: A balancing act 

      Jakola, Asgeir Store (Doktoravhandlinger ved NTNU, 1503-8181; 2013:158, Doctoral thesis, 2013)

    • Ritualer ved sykdom og død 

      Røen, Ingebrigt; Hirsch, Anne (Chapter, 2016)

    • RNA in DNA repair 

      Vågbø, Cathrine Broberg; Slupphaug, Geir (Peer reviewed; Journal article, 2020)
      Our genome is constantly subject to damage from exogenous and endogenous sources, and cells respond to such damage by initiating a DNA damage response (DDR). Failure to induce an adequate DDR can result in increased mutation ...

    • RNA metabolism guided by RNA modifications: The role of SMUG1 in rRNA quality control 

      Lirussi, Lisa; Demir, Özlem; You, Panpan; Sarno, Antonio; Amaro, Rommie E.; Nilsen, Hilde (Peer reviewed; Journal article, 2021)
      RNA modifications are essential for proper RNA processing, quality control, and maturation steps. In the last decade, some eukaryotic DNA repair enzymes have been shown to have an ability to recognize and process modified ...

    • RNA motif discovery: a computational overview 

      Achar, Avinash; Sætrom, Pål (Journal article; Peer reviewed, 2015)
      Genomic studies have greatly expanded our knowledge of structural non-coding RNAs (ncRNAs). These RNAs fold into characteristic secondary structures and perform specific-structure dependent biological functions. Hence RNA ...

    • RNA-Integrity and 8-Isoprostane Levels Are Stable in Prostate Tissue Samples Upon Long-Term Storage at −80°C 

      Dybos, Sandra Amalie; Winje Brustad, Åge; Rolfseng, Toril F.Langvik; Kvam, Solveig; Olsen, Oddrun Elise; Halgunset, Jostein; Skogseth, Haakon (Peer reviewed; Journal article, 2020)
      Sampling of prostate tissue (n = 97) was performed in conjunction with planned radical prostatectomies, in collaboration with Biobank1®. The tissue used in this study was collected during the period 2003-2016, quickly ...

    • Road traffic noise and registry based use of sleep medication 

      Evandt, Jorunn; Oftedal, Bente Margaret; Krog, Norun Hjertager; Skurtveit, Svetlana; Nafstad, Per; Schwarze, Per E; Skovlund, Eva; Houthuijs, Danny; Aasvang, Gunn Marit (Journal article; Peer reviewed, 2017)
      Background Road traffic noise has been associated with adverse health effects including sleep disturbances. Use of sleep medication as an indicator of sleeping problems has rarely been explored in studies of the effects ...

    • Road traffic noise, air pollution and incident cardiovascular disease: A joint analysis of the HUNT, EPIC-Oxford and UK Biobank cohorts 

      Cai, Yutong; Hodgson, Susan; Blangiardo, Marta; Gulliver, John; Morley, David; Fecht, Daniela; Vienneau, Danielle; de Hoogh, Kees; Key, Tim; Hveem, Kristian; Elliott, Paul; Hansell, Anna L. (Peer reviewed; Journal article, 2018)
      Background This study aimed to investigate the effects of long-term exposure to road traffic noise and air pollution on incident cardiovascular disease (CVD) in three large cohorts: HUNT, EPIC-Oxford and UK Biobank. ...

    • A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach 

      Rochester, Lynn; Mazza, Claudia; Mueller, Arne; Caulfield, Brian; McCarthy, Marie; Becker, Clemens; Miller, Ram; Piraino, Paolo; Viceconti, Marco; Dartee, Wim P; Garcia-Aymerich, Judith; Aydemir, Aida A; Vereijken, Beatrix; Arnera, Valdo; Ammour, Nadir; Jackson, Michael; Hache, Tilo; Roubenoff, Ronenn (Journal article, 2020)
      Helsevesenet har måttet tilpasse seg raskt til COVID-19, og dette har igjen understreket et presserende behov for verktøy for å lette fjernbesøk og overvåking. Digital helseteknologi, inkludert kroppsbrukte enheter, tilbyr ...

    • Robust bacterial co-occurence community structures are independent of r- and K-selection history. 

      Pettersen, Jakob Peder; Gundersen, Madeleine S.; Almaas, Eivind (Peer reviewed; Journal article, 2021)
      Selection for bacteria which are K-strategists instead of r-strategists has been shown to improve fish health and survival in aquaculture. We considered an experiment where microcosms were inoculated with natural seawater ...

    • Robust Distance Measures for kNN Classification of Cancer Data 

      Ehsani, Rezvan; Drabløs, Finn (Peer reviewed; Journal article, 2020)
      The k-Nearest Neighbor (kNN) classifier represents a simple and very general approach to classification. Still, the performance of kNN classifiers can often compete with more complex machine-learning algorithms. The core ...

    • Robust DNA repair in PAXX-deficient mammalian cells 

      Dewan, Alisa Elinsdatter; Xing, Mengtan; Lundbæk, Marie Benner; Gago-Fuentes, Raquel; Beck, Carole; Aas, Per Arne; Liabakk, Nina-Beate; Sæterstad, Siri; Khac Thanh Phong, Chau; Kavli, Bodil Merete; Oksenych, Valentyn (Journal article; Peer reviewed, 2018)
      To ensure genome stability, mammalian cells employ several DNA repair pathways. Nonhomologous DNA end joining (NHEJ) is the DNA repair process that fixes double-strand breaks throughout the cell cycle. NHEJ is involved in ...

    • Robustness of In-Laboratory and Daily-Life Gait Speed Measures over One Year in High Functioning 61- To 70-Year-Old Adults 

      Rojer, Anna G.M.; Coni, Alice; Mellone, Sabato; Van Ancum, Jeanine M.; Vereijken, Beatrix; Helbostad, Jorunn L.; Taraldsen, Kristin; Mikolaizak, Stefanie; Becker, Clemens; Aminian, Kamiar; Trappenburg, Marijke C.; Meskers, Carel G.M.; Maier, Andrea B.; Pijnappels, Mirjam (Peer reviewed; Journal article, 2021)
      Introduction: Gait speed is a simple and safe measure with strong predictive value for negative health outcomes in clinical practice, yet in-laboratory gait speed seems not representative for daily-life gait speed. This ...

    • Robustness of VMAT and 3DCRT plans toward setup errors in radiation therapy of locally advanced left-sided breast cancer with DIBH 

      Jensen, Christer André; Roa, Ana María Acosta; Johansen, Marie; Lund, Jo-Åsmund; Frengen, Jomar (Journal article; Peer reviewed, 2018)
      Purpose The aim of our study was to evaluate and compare the robustness of treatment plans produced using the volumetric modulated arc-therapy (VMAT) and the standard three-dimensional conformal radiotherapy (3DCRT) ...

    • A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres 

      Mentegari, Elisa; Bertoletti, Federica; Kissova, Miroslava; Zucca, Elisa; Galli, Silvia; Tagliavini, Giulia; Garbelli, Anna; Maffia, Antonio; Bione, Silvia; Ferrari, Elena; d'Adda di Fagagna, Fabrizio; Francia, Sofia; Sabbioneda, Simone; Chen, Liuh-Yow; Lingner, Joachim; Bergoglio, Valerie; Hoffmann, Jean-Sebastien; Hübscher, Ulrich; Crespan, Emmanuele; Maga, Giovanni (Peer reviewed; Journal article, 2021)
      Telomerase negative cancer cell types use the Alternative Lengthening of Telomeres (ALT) pathway to elongate telomeres ends. Here, we show that silencing human DNA polymerase (Pol λ) in ALT cells represses ALT activity and ...