Blar i Institutt for datateknologi og informatikk på forfatter "Alsøe, Lene"
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SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde (Journal article; Peer reviewed, 2019)Telomerase biogenesis is a complex process where several steps remain poorly understood. Single-strand-selective uracil-DNA glycosylase (SMUG1) associates with the DKC1-containing H/ACA ribonucleoprotein complex, which is ... -
TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno; Krokan, Hans Einar; Sarno, Antonio; Alsøe, Lene; Berdal, Jan-Erik; Sætrom, Pål; Nilsen, Hilde; Domanska, Diana (Peer reviewed; Journal article, 2023)Improved transcriptomic sequencing technologies now make it possible to perform longitudinal experiments, thus generating a large amount of data. Currently, there are no dedicated or comprehensive methods for the analysis ...