Browsing Institutt for datateknologi og informatikk by Author "Fernandes, Jorge Manuel de Oliveira"
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DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden
Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira (Journal article; Peer reviewed, 2023)Phenotypic plasticity of metabolism and growth are essential for adaptation to new environmental conditions, such as those experienced during domestication. Epigenetic regulation plays a key role in this process but the ... -
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2021)In vertebrates, the somatotropic axis comprising the pituitary gland, liver and muscle plays a major role in myogenesis. Its output in terms of muscle growth is highly affected by nutritional and environmental cues, and ... -
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2020)The historically recent domestication of fishes has been essential to meet the protein demands ofa growing human population. Selection for traits of interest during domestication is a complexprocess whose epigenetic basis ...