Browsing Institutt for kjemi by Author "Norges teknisk-naturvitenskapelige universitet, Fakultet for naturvitenskap,Institutt for kjemi"
Now showing items 21-40 of 54
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Stereoselektiv framstilling av maskerte aminosyrer frå pyrrolderivat og kirale sulfinimin
Ringheim, Ingvild (Master thesis, 2015)I denne oppgåva vart det fokusert på kva påverknad ulike substituentar på pyrrol har å seia for regio- og stereoselektiviteten i EAS-reaksjonar med sulfiniminet \textbf{1} som elektrofil, som vist i Skjema 3. Pyrrol-glysinprodukta ... -
Studies on Gold-Nitrone Chemistry
Jónsson, Helgi Freyr (Master thesis, 2017)The gold(I)-nitrone catalysed cyclotrimerization of diaryl propargyl acetals was studied. Gold(I)-nitrone and gold(I)/gold(III)-oxadiazole complexes were also synthesised. -
Syntese av nitrogenholdige heterosykler med kirale substituenter - Utforsking av JAK2 hemming
Berg, Håvard (Master thesis, 2015)Siden Janus kinasene (JAK) ble oppdaget på tidlig 90-tall har de vært et viktig forsknings område innen medisinsk kjemi. Ved å hemme signaler fra JAK kan vekst av kreftceller kontrolleres, og dessuten mange andre inflammatoriske ... -
Syntese og karakterisering av nye fenotiazin-fargestoffer til Dye-Sensitized Solar Cells (DSSC)
Vold, Martin Furru (Master thesis, 2017)I jakten på nye måter å utnytte solenergi har mye fokus blitt rettet mot fotovoltaiske celler basert på DSSC (Dye-Sensitized Solar Cell)-teknologi. Slike celler kan baseres på kommersielt tilgjengelige og relativt billige ... -
Synthesis and Biological Evaluation of Furo[2,3-d]pyrimidines as EGFR Tyrosine Kinase Inhibitors
Nervik, Sondre (Master thesis, 2015)The work performed in this master s thesis has contributed to a larger ongoing study on the development of new epidermal growth factor (EGFR) tyrosine kinase inhibitors, intended for use in cancer chemotherapy. The ... -
Synthesis and Characterisation of Nanoporous VCuAPO-5 for Propene Oxidation
Sjursen, Kenneth Røsvik (Master thesis, 2015)In this work a synthesis route for the incorporation of vanadium and copper into the framework of AlPO-5 by isomorphous substitution been investigated. The resulting product, VCuAPO-5 have was characterised by x-ray ... -
Synthesis and Characterization of New Organic Dyes for Dye-Sensitized Solar Cells (DSSC)
Kringhaug, Henrik Holthe (Master thesis, 2016)Advances in components of dye-sensitized solar cells (DSSCs) are required to improve upon current technology and to make DSSCs a feasible competitor to traditional solar cells. The light harvesting dye is one of the ... -
Synthesis and Characterization of Phenothiazine - Graphene Hybrid Materials for Dye-Sensitized Solar Cells (DSSC)
Fougner, Hugo In'T Veld (Master thesis, 2017)The Dye-Sensitized Solar cells (DSSCs), first described by Grätzel and O'Reagan in 1991, are to date one of the least improved photovoltaic technologies compared to similar third generation solar cells. This fact, opens ... -
Synthesis of 1,2,3-Triazole Peptidomimetics for Antimicrobial Evaluation
Høisæter, Karen Karolina (Master thesis, 2018)The scope of this thesis has been to synthesise small cationic amphiphilic 1,2,3-triazoles with multiple lipophilic and cationic groups. These will be tested for antimicrobial activity. The target compound 7* and 8 were ... -
Synthesis of 10H-Phenothiazines for Investigation of Π-linker Effect in Dye-Sensitized Solar Cells
Uggerud, Nora (Master thesis, 2016)A global challenge is that electricity is predominantly generated unsustainably. To improve on the situation, more of the electricity should be generated directly from sunlight by solar cells. Commercial solar cells based ... -
Synthesis of 5-Aryl-Pyrrolo[2,3-d]pyrimidines and Their Bioactivity
Reiersølmoen, Ann Christin (Master thesis, 2016)The epidermal growth factor receptor tyrosine kinase is one of the more important targets in targeted cancer therapy. However, on prolonged administration of EGFR inhibitors, resistance emerge, which in 50% of the cases ... -
Synthesis of 6-Aryl-pyrrolopyrimidines - Effect of ortho Substituents on EGFR Inhibitory Activity
Henriksen, Silje (Master thesis, 2015)The goal of this project was to synthesise new and active epidermal growth factor receptor (EGFR) inhibitors which hopefully can be used in treatment of cancer. Seven new biological active pyrrolopyrimidines have been ... -
Synthesis of Cationic Amphiphiles Based on L-Tartaric Acid Scaffolds for Antimicrobial Screening
Álvarez Fernández, Hadrián (Master thesis, 2018)Infectious diseases are still one of the main causes of death nowadays. The development of new antibiotics it is still as necessary as it was when penicillin was first discovered in 1929. As bacteria grow resistant to ... -
Synthesis of Enantiopure Precursors for Clenbuterol
Blindheim, Fredrik Heen (Master thesis, 2017)The primary goal of this thesis was to synthesize enantiopure (R)-clenbuterol and its precursors by using enzymes as chiral catalysts. As a secondary goal, the substrate acceptance of ketoreductase 228 (KRED 228) was ... -
Synthesis of enantiopure β-blocker (S)-metoprolol and derivatives by lipase catalysis
Bøckmann, Pål Lønnegraff (Master thesis, 2016)The goal of this thesis was to synthesize the enantiomerically pure β-blocker (S)-metoprolol through the use of biocatalysis and elucidate potential factors that may influence the selectivity of enzymes. The model substrate ... -
Synthesis of Enantiopure β-Blocker (S)-Practolol by Lipase Catalysis
Austli, Guro Buaas (Master thesis, 2018)Finding a more environmentally friendly method for synthesis of enantiopure drugs is important, due to the principles of green chemistry and to avoid potential side effects from racemic drugs. The aim for this thesis was ... -
Synthesis of Fused Benzene Amphiphiles
Valderhaug, Solveig (Master thesis, 2018)The discovery of antibiotics have made some major advances in treatment of infectious diseases, other medical treatments and surgery. For the past few decades, overuse, inappropriate prescribing and extensive use of ... -
Synthesis of fused benzene amphiphiles for antimicrobial evaluation
Myreng, Kristian Njerve (Master thesis, 2017)See attached document. -
Synthesis of Phenothiazine Derivatives as Potential Non-Fullerene Acceptors for Organic Solar Cells
Hoff, Ingvild (Master thesis, 2018)Global emissions need to decline steeply towards 2020, according to the International Energy Agency (IEA). As stated by the IEA, solar photovoltaics accounted for 27% of the overall renewable energy growth in 2017. Organic ... -
Synthesis of Pyrrolopyrimidines as CSF-1R Kinase Inhibitors
Larsen, Kristin Uhlving (Master thesis, 2016)