Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care
Norman, Mikael; Padkær Petersen, Jesper; Stensvold, Hans Jørgen; Thorkelsson, Thordur; Helenius, Kjell; Brix Andersson, Charlotte; Ørum Cueto, Heidi; Domellöf, Magnus; Gissler, Mika; Heino, Anna; Håkansson, Stellan; Jonsson, Baldvin; Klingenberg, Claus Andreas; Lehtonen, Liisa; Metsäranta, Marjo; Rønnestad, Arild Erland; Trautner, Simon; Vatne, Anlaug; Støen, Ragnhild; Brække, Kristin; Reigstad, Hallvard
Peer reviewed, Journal article
Published version
Permanent lenke
https://hdl.handle.net/11250/3080111Utgivelsesdato
2023Metadata
Vis full innførselSamlinger
- Institutt for klinisk og molekylær medisin [3691]
- Publikasjoner fra CRIStin - NTNU [40022]
- St. Olavs hospital [2698]
Sammendrag
Aim
Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis.
Methods
Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm birth rates, case-mix, perinatal interventions, neonatal morbidity and survival to hospital discharge in very (<32 weeks) and extremely preterm infants (<28 weeks of gestational age) were compared.
Results
Out of 287 642 infants born alive, 16 567 (5.8%) were preterm, 2389 (0.83%) very preterm and 800 (0.28%) were extremely preterm. In very preterm infants, exposure to antenatal corticosteroids varied from 85% to 98%, live births occurring at regional centres from 48% to 100%, surfactant treatment from 28% to 69% and use of mechanical ventilation varied from 13% to 77% (p < 0.05 for all comparisons). Significant regional variations within and between countries were also seen in capacity in neonatal care, case-mix and number of admissions, whereas there were no statistically significant differences in survival or major neonatal morbidities.
Conclusion
Management of very preterm infants exhibited significant regional variations in the Nordic countries.