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Prevalence and clinical characteristics of patients with obsessive-compulsive disorder in first-episode psychosis

Hagen, Kristen; Hansen, Bjarne; Joa, Inge; Larsen, Tor Ketil
Journal article, Peer reviewed
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1471-244X-13-156.pdf (190.2Kb)
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http://hdl.handle.net/11250/301280
Utgivelsesdato
2013
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  • Institutt for nevromedisin og bevegelsesvitenskap [2260]
  • Publikasjoner fra CRIStin - NTNU [26591]
Originalversjon
BMC Psychiatry 2013, 13(156)   10.1186/1471-244X-13-156
Sammendrag
Background: Obsessive-compulsive disorder (OCD) in patients with psychotic disorders has been reported to be a

frequent co-morbid disorder in patients with psychotic disorders. The aim of the study determine the prevalence of

OCD in first-episode psychosis and the relationship with clinical characteristics.

Methods: First-episode psychosis patients (N = 246) consecutively admitted to a comprehensive early psychosis

program were assessed for OCD with the Structured Clinical Interview for DSM-IV. Symptom assessment measures

were the Positive and Negative Syndrome Scale, Global Assessment of Functioning, and the Clinician Rating Scale.

Results: Twenty-six patients (10.6%) fulfilled the criteria for OCD. Patients with comorbid OCD were younger, had

more depressive symptoms and a higher rate of suicidal plans or attempts at index point compared to patients

without OCD. The two groups did not differ with respect to other demographic variables or severity of psychotic

symptoms.

Conclusion: OCD is a significant comorbid disorder in patients with first-episode psychosis. Since treatment

procedures are different, systematic screening for OCD is warranted.

Keywords: Obsessive-compulsive disorder, First-episode psychosis, Schizophrenia, Prevalence, Comorbidity.
Utgiver
BioMed Central
Tidsskrift
BMC Psychiatry

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