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dc.contributor.authorCarbon, Seth J.
dc.contributor.authorDouglass, Eric
dc.contributor.authorGood, Benjamin M
dc.contributor.authorUnni, Deepak R
dc.contributor.authorHarris, Nomi L.
dc.contributor.authorMungall, Christopher J.
dc.contributor.authorBasu, Siddartha
dc.contributor.authorChisholm, Rex L.
dc.contributor.authorDodson, Robert J.
dc.contributor.authorHartline, Eric
dc.contributor.authorFey, Petra
dc.contributor.authorThomas, Paul D.
dc.contributor.authorAlbou, Laurent-Philippe
dc.contributor.authorEbert, Dustin
dc.contributor.authorKesling, Michael J
dc.contributor.authorMi, Huaiyu
dc.contributor.authorMuruganujan, Anushya
dc.contributor.authorHuang, Xiaosong
dc.contributor.authorMushayahama, Tremayne
dc.contributor.authorLaBonte, Sandra A.
dc.contributor.authorSiegele, Deborah A.
dc.contributor.authorAntonazzo, Giulia
dc.contributor.authorAttrill, Helen
dc.contributor.authorBrown, Nick H.
dc.contributor.authorGarapati, Phani
dc.contributor.authorMarygold, Steven J.
dc.contributor.authorTrovisco, Vitor
dc.contributor.authordos Santos, Gil
dc.contributor.authorFalls, Kathleen
dc.contributor.authorTabone, Christopher
dc.contributor.authorZhou, Pinglei
dc.contributor.authorGoodman, Joshua L.
dc.contributor.authorStrelets, Victor B.
dc.contributor.authorThurmond, Jim
dc.contributor.authorGarmiri, Penelope
dc.contributor.authorIshtiaq, Rizwan
dc.contributor.authorRodríguez-López, Milagros
dc.contributor.authorAcencio, Marcio Luis
dc.contributor.authorKuiper, Martin
dc.contributor.authorLægreid, Astrid
dc.contributor.authorLogie, Colin
dc.contributor.authorLovering, Ruth C.
dc.contributor.authorKramarz, Barbara
dc.contributor.authorSaverimuttu, Shirin C.C.
dc.contributor.authorPinheiro, Sandra M.
dc.contributor.authorGunn, Heather
dc.contributor.authorSu, Renzhi
dc.contributor.authorThurlow, Katherine E.
dc.contributor.authorChibucos, Marcus
dc.contributor.authorGiglio, Michelle
dc.contributor.authorNadendla, Suvarna
dc.contributor.authorMunro, James
dc.contributor.authorJackson, Rebecca
dc.contributor.authorDuesbury, Margaret J.
dc.contributor.authordel-Toro, Noemi
dc.contributor.authorMeldal, Birgit H.M.
dc.contributor.authorPaneerselvam, Kalpana
dc.contributor.authorPerfetto, Livia
dc.contributor.authorPorras, Pablo
dc.contributor.authorOrchard, Sandra
dc.contributor.authorShrivastava, Anjali
dc.description.abstractThe Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The new GO-CAM annotation framework was notably improved, and we formalized the model with a computational schema to check and validate the rapidly increasing repository of 2838 GO-CAMs. In addition, we describe the impacts of several collaborations to refine GO and report a 10% increase in the number of GO annotations, a 25% increase in annotated gene products, and over 9,400 new scientific articles annotated. As the project matures, we continue our efforts to review older annotations in light of newer findings, and, to maintain consistency with other ontologies. As a result, 20 000 annotations derived from experimental data were reviewed, corresponding to 2.5% of experimental GO annotations. The website ( was redesigned for quick access to documentation, downloads and tools. To maintain an accurate resource and support traceability and reproducibility, we have made available a historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations.en_US
dc.publisherOxford University Pressen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleThe Gene Ontology resource: enriching a GOld mineen_US
dc.title.alternativeThe Gene Ontology resource: enriching a GOld mineen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.source.journalNucleic Acids Research (NAR)en_US

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal