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dc.contributor.authorBerglund, Ida Johnsen
dc.contributor.authorVesterbekkmo, Elisabeth Kleivhaug
dc.contributor.authorRetterstøl, Kjetil
dc.contributor.authorAnderssen, Sigmund Alfred
dc.contributor.authorSingh, Maria A. Fiatarone
dc.contributor.authorHelge, Jørn Wulff
dc.contributor.authorLydersen, Stian
dc.contributor.authorWisløff, Ulrik
dc.contributor.authorStensvold, Dorthe
dc.date.accessioned2022-02-22T15:27:22Z
dc.date.available2022-02-22T15:27:22Z
dc.date.created2021-11-18T10:36:44Z
dc.date.issued2021
dc.identifier.citationMayo Clinic Proceedings: Innovations, Quality & Outcomes (MCP:IQ&O). 2021, 5 (5), 859-871.en_US
dc.identifier.issn2542-4548
dc.identifier.urihttps://hdl.handle.net/11250/2980837
dc.description.abstractObjective: To examine whether 5 years of high-intensity interval training (HIIT) increases high-density lipoprotein cholesterol (HDL-C) concentration more than moderate-intensity continuous training (MICT) and control (CON) in older men and women. Methods: A total of 1567 older adults (790 [50.4%] women) were randomized (2:1:1) to either CON (n=780; asked to follow the national recommendations for physical activity) or 2 weekly sessions of HIIT (10-minute warm-up followed by 4×4-minute intervals at ∼90% of peak heart rate) or MICT (50 minutes of continuous work at ∼70% of peak heart rate). Serum HDL-C concentration was measured by standard procedures at baseline and at 1 year, 3 years, and 5 years. The study took place between August 21, 2012, and June 31, 2018. Linear mixed models were used to determine between-group differences during 5 years using the per protocol approach. Results: Men in HIIT had a smaller reduction in HDL-C (−1.2%) than men in CON (−6.9%) and MICT (−7.8%) after 5 years (P=.01 and P=.03 for CON vs HIIT and MICT vs HIIT, respectively). No effect of exercise intensity on HDL-C was seen in women. Changes in peak oxygen uptake were associated with changes in HDL-C in both men and women, whereas changes in body weight and fat mass were not. Conclusion: In men, HIIT seems to be the best strategy to prevent a decline in HDL-C during a 5-year period. No effect of exercise intensity was seen for older women.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleThe Long-term Effect of Different Exercise Intensities on High-Density Lipoprotein Cholesterol in Older Men and Women Using the Per Protocol Approach: The Generation 100 Studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber859-871en_US
dc.source.volume5en_US
dc.source.journalMayo Clinic Proceedings: Innovations, Quality & Outcomes (MCP:IQ&O)en_US
dc.source.issue5en_US
dc.identifier.doi10.1016/j.mayocpiqo.2021.07.002
dc.identifier.cristin1955855
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal