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dc.contributor.authorKjønås, Didrik
dc.contributor.authorDahle, Gro
dc.contributor.authorSchirmer, Henrik
dc.contributor.authorMalm, Siri
dc.contributor.authorEidet, Jo
dc.contributor.authorAaberge, Lars
dc.contributor.authorSteigen, Terje
dc.contributor.authorAakhus, Svend
dc.contributor.authorBusund, Rolf
dc.contributor.authorRøsner, Assami
dc.date.accessioned2022-02-02T14:37:16Z
dc.date.available2022-02-02T14:37:16Z
dc.date.created2021-12-13T11:19:05Z
dc.date.issued2021
dc.identifier.issn2398-8835
dc.identifier.urihttps://hdl.handle.net/11250/2976716
dc.description.abstractObjectives Transcatheter aortic valve implantation (TAVI)-specific risk scores have been developed based on large registry studies. Our aim was to evaluate how both surgical and novel TAVI risk scores performed in predicting all cause 30-day mortality. In addition, we wanted to explore the validity of our own previously developed model in a separate and more recent cohort. Methods The derivation cohort included patients not eligible for open surgery treated with TAVI at the University Hospital of North Norway (UNN) and Oslo University Hospital (OUS) from February 2010 through June 2013. From this cohort, a logistic prediction model (UNN/OUS) for all cause 30-day mortality was developed. The validation cohort consisted of patients not included in the derivation cohort and treated with TAVI at UNN between June 2010 and April 2017. EuroSCORE, Logistic EuroSCORE, EurosSCORE 2, STS score, German AV score, OBSERVANT score, IRRMA score, and FRANCE-2 score were calculated for both cohorts. The discriminative accuracy of each score, including our model, was evaluated by receiver operating characteristic (ROC) analysis and compared using DeLong test where P< .05 was considered statistically significant. Results The derivation cohort consisted of 218 and the validation cohort of 241 patients. Our model showed statistically significant better accuracy than all other scores in the derivation cohort. In the validation cohort, the FRANCE-2 had a significantly higher predictive accuracy compared to all scores except the IRRMA and STS score. Our model showed similar results. Conclusion Existing risk scores have shown limited accuracy in predicting early mortality after TAVI. Our results indicate that TAVI-specific risk scores might be useful when evaluating patients for TAVI.en_US
dc.language.isoengen_US
dc.publisherWiley Open Accessen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titleRisk scores for prediction of 30-day mortality after transcatheter aortic valve implantation: Results from a two-center study in Norwayen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.source.volume4en_US
dc.source.journalHealth Science Reportsen_US
dc.identifier.doi10.1002/hsr2.283
dc.identifier.cristin1967667
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal