dc.contributor.author | Heggstad, Norvald | |
dc.contributor.author | Hafström, Maria | |
dc.date.accessioned | 2021-04-26T13:26:47Z | |
dc.date.available | 2021-04-26T13:26:47Z | |
dc.date.created | 2020-08-05T15:50:52Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Acta Paediatrica. 2020, . | en_US |
dc.identifier.issn | 0803-5253 | |
dc.identifier.uri | https://hdl.handle.net/11250/2739690 | |
dc.description.abstract | Aim: To identify the aetiology and outcome of seizure-like events leading to hospital referrals in infants and to identify early predictors of epilepsy and delayed neurodevelopment. Methods: This Norwegian population-based study focused on all children born in Sør-Trøndelag county, who were up to one year of age in 2014-2015. They were identified by diagnostic codes for seizure-like events and electroencephalography (EEG) examinations. Hospital records were examined up to 1.5 years of age. Results: The one-year prevalence of seizure-like events was 1.5% (114/7430). Epilepsy was diagnosed in 17%, 57% had non-epileptic paroxysmal events (NEPE), 16% had febrile seizures, and 10% had other acute symptomatic epileptic seizures. Neurodevelopmental delay occurred in 21%. The cumulative incidence was 0.22% for epilepsy and 0.79% for NEPE. Abnormal brain magnetic resonance imaging, abnormal first EEGs and neonatal care increased the likelihood of epilepsy and delayed development. Identifying situation-related factors decreased the epilepsy risk. Occurrence at a younger age increased the risk of delayed development. Absence of unambiguous motor symptoms was less common in epilepsy than in NEPE. Conclusion: Seizure-like events were common in infants and most were not caused by epilepsy. Specific anamnestic clues, and detailed descriptions of the entire event, helped to predict adverse outcomes. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley Online Library | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Seizure-like events leading to hospital referrals in infants: A retrospective population-based study | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 0 | en_US |
dc.source.journal | Acta Paediatrica | en_US |
dc.identifier.doi | 10.1111/apa.15467 | |
dc.identifier.cristin | 1821879 | |
dc.description.localcode | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. © 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |