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DNA barcodes provide insights into the diversity and biogeography of the non-biting midge Polypedilum (Diptera, Chironomidae) in South America
(Peer reviewed; Journal article, 2023)South America, particularly within its tropical belt, is renowned for its unparalleled high levels of species richness, surpassing other major biomes. Certain neotropical areas harbor fragmented knowledge of insect diversity ... -
DNA barcodes successfully delimit morphospecies in a superdiverse insect genus
(Journal article; Peer reviewed, 2018)Polypedilum Kieffer (Diptera: Chironomidae), with 520 currently known species worldwide, can be extremely difficult to identify species level based on the morphology. We used 3,670 cytochrome c oxidase subunit I (COI) ... -
DNA barcoding for species identification of insect skins: A test on Chironomidae (Diptera) pupal exuviae
(Journal article; Peer reviewed, 2017)Chironomidae (Diptera) pupal exuviae samples are commonly used for biological monitoring of aquatic habitats. DNA barcoding has proved useful for species identification of chironomid life stages containing cellular tissue, ... -
DNA barcoding of Aphelopus Dalman (Hymenoptera, Dryinidae) from China, with descriptions of four new species
(Journal article; Peer reviewed, 2022) -
DNA barcoding of the northern Northeast Atlantic skates (Chondrichthyes, Rajiformes), with remarks on the widely distributed starry ray
(Journal article; Peer reviewed, 2014)The skate fauna in the northern Northeast (NE) Atlantic is poorly investigated, and misidentifications are common. Here, ‘DNA barcoding’ was used to analyse 105 specimens of 15 species previously reported from the area to ... -
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
(Journal article; Peer reviewed, 2016)Well-known epigenetic DNA modifications in mammals include the addition of a methyl group and a hydroxyl group to cytosine, resulting in 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) respectively. In contrast, ... -
DNA compaction induced by a cationic polymer or surfactant impact gene expression and DNA degradation
(Journal article; Peer reviewed, 2014)There is an increasing interest in achieving gene regulation in biotechnological and biomedical applications by using synthetic DNA-binding agents. Most studies have so far focused on synthetic sequence-specific DNA-binding ... -
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers. Influence of Peptide Charge
(Peer reviewed; Journal article, 2023)Nucleic acid delivery to cells is an important therapeutic strategy that requires the transport of nucleic acids to intracellular compartments and their protection from enzymatic degradation. This can be achieved through ... -
DNA double-strand breaks in relation to persistent organic pollutants in a fasting seabird
(Journal article; Peer reviewed, 2014)Lipophilic persistent organic pollutants (POPs) are released from fat reserves during fasting, causing increased blood concentrations. Thus, POPs represent a potential anthropogenic stressor during fasting periods. We ... -
DNA double‐strand breaks in Arctic char (Salvelinus alpinus) from Bjørnøya in the Norwegian Arctic
(Journal article; Peer reviewed, 2019)High levels of organochlorine contaminants (OCs) have been found in arctic char (Salvelinus alpinus) from Lake Ellasjøen, Bjørnøya (Norwegian Arctic). The aim of the present study was to investigate the potential genotoxic ... -
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
(Peer reviewed; Journal article, 2020)The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ... -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
(Peer reviewed; Journal article, 2021)Background and aims Atherogenesis involves a complex interaction between immune cells and lipids, processes greatly influenced by the vascular smooth muscle cell (VSMC) phenotype. The DNA glycosylase NEIL3 has previously ... -
DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden
(Journal article; Peer reviewed, 2023)Phenotypic plasticity of metabolism and growth are essential for adaptation to new environmental conditions, such as those experienced during domestication. Epigenetic regulation plays a key role in this process but the ... -
DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation
(Journal article; Peer reviewed, 2020)Background Prostate cancer (PCa) has the highest incidence rates of cancers in men in western countries. Unlike several other types of cancer, PCa has few genetic drivers, which has led researchers to look for additional ... -
DNA metabarcoding adds valuable information for management of biodiversity in roadside stormwater ponds
(Journal article; Peer reviewed, 2019)Stormwater ponds are used to compensate for the adverse effects that road runoff might have on the natural environment. Depending on their design and placement, stormwater ponds can act as both refugia and traps for local ... -
DNA metabarcoding and spatial modelling link diet diversification with distribution homogeneity in European bats
(Peer reviewed; Journal article, 2020)Inferences of the interactions between species’ ecological niches and spatial distribution have been historically based on simple metrics such as low-resolution dietary breadth and range size, which might have impeded the ... -
DNA Metabarcoding of Preservative Ethanol Reveals Changes in Invertebrate Community Composition Following Rotenone Treatment
(Peer reviewed; Journal article, 2022)The botanical compound rotenone is extensively used to eradicate populations and reduce the negative impacts of freshwater invasive animals. The method is controversial as non-target organisms often are negatively affected, ... -
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
(Peer reviewed; Journal article, 2022)Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ... -
DNA methylation data by sequencing: experimental approaches and recommendations for tools and pipelines for data analysis
(Journal article; Peer reviewed, 2019)Sequencing technologies have changed not only our approaches to classical genetics, but also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide epigenetic patterns of DNA methylation ... -
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients
(Peer reviewed; Journal article, 2022)Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. We aimed at identifying age-related molecular differences ...