Blar i Publikasjoner fra CRIStin - NTNU på tittel
Viser treff 7499-7518 av 37257
-
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
(Journal article; Peer reviewed, 2011)Background Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target ... -
Cyclic Arginine–Glycine–Aspartate-Decorated Lipid Nanoparticle Targeting toward Inflammatory Lesions Involves Hitchhiking with Phagocytes
(Peer reviewed; Journal article, 2021)Active-targeting nanomedicine formulations have an intricate in vivo behavior. Nanomedicines developed to target endothelial αvβ3-integrin are recently demonstrated to display extensive uptake by circulating phagocytes. ... -
Cyclic behavior and strain energy-based fatigue damage analysis of mooring chains high strength steel
(Peer reviewed; Journal article, 2020)This study investigates the low-cycle fatigue behavior of mooring chains high-strength steel grade R4 under different strain amplitudes and strain ratios at room temperature. A fatigue test program has been carried out on ... -
Cyclic cold isostatic pressing and improved particle packing of coarse grained oxide ceramics for refractory applications
(Journal article; Peer reviewed, 2018)This study investigated the cold isostatic pressing of coarse grained alumina refractories applying either a cyclic pressure increase or a cycling at maximum pressure. Additionally the effects of the maximum pressure and ... -
Cyclic Compression Testing of Three Elastomer Types— A Thermoplastic Vulcanizate Elastomer, a Liquid Silicone Rubber and Two Ethylene-Propylene-Diene Rubbers
(Peer reviewed; Journal article, 2022)Thermoplastic elastomer vulcanizate (TPV) and liquid silicone rubber (LSR) are replacement candidates for ethylene-propylene-diene rubbers (EPDM), as they offer the possibility for twocomponent injection moulding. In this ... -
Cyclic fatigue in unlined hydro tunnels caused by pressure transients
(Peer reviewed; Journal article, 2021)Regulated hydropower is currently the most capable load balancing technology for the future renewable energy system which will be characterized by a large share of unregulated energy from solar and wind power. Increased ... -
Cyclic oedometer swelling tests on rocks from North-Central Luzon, Philippines
(Chapter, 2020)Tunnels passing through swelling rocks are subjected to stability problems as moisture changes affect the material properties of the rocks. The drying out process during construction may cause local contraction stresses ... -
Cyclicity in the Drury-Arveson space and other weighted Besov spaces
(Peer reviewed; Journal article, 2023) -
Cycling at Altitude: Lower Absolute Power Output as the Main Cause of Lower Gross Efficiency
(Peer reviewed; Journal article, 2019)Background: Although cyclists often compete at altitude, the effect of altitude on gross efficiency (GE) remains inconclusive. Purpose: To investigate the effect of altitude on GE at the same relative exercise intensity ... -
Cyclodextrin inhibits zinc corrosion by destabilizing point defect formation in the oxide layer
(Journal article; Peer reviewed, 2018)Corrosion inhibitors are added in low concentrations to corrosive solutions for reducing the corrosion rate of a metallic material. Their mechanism of action is typically the blocking of free metal surface by adsorption, ... -
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
(Journal article, 2016)Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol concentrations. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause ... -
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
(Journal article, 2017)Cholesterol crystals (CC) are abundant in atherosclerotic plaques and promote inflammatory responses via the complement system and inflammasome activation. Cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (BCD) is a ... -
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
(Journal article; Peer reviewed, 2017)Cholesterol crystals (CC) are abundant in atherosclerotic plaques and promote inflammatory responses via the complement system and inflammasome activation. Cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (BCD) is a ... -
Cyclodextrin triggered dimensional changes of polysaccharide nanogel integrated hydrogels at nanometer resolution
(Journal article; Peer reviewed, 2013)High resolution monitoring of dimensional changes of cholesterol bearing pullulan (CHP) hydrogel was performed as a model for materials dimensional changes associated with drug delivery. Hydrogels consisting of methacryloyl ... -
Cyclodextrins as carriers for organic corrosion inhibitors in organic coatings
(Journal article; Peer reviewed, 2017) -
The Cyclooxygenase 2 inhibitor etoricoxib as adjunctive therapy in tuberculosis impairs macrophage control of mycobacterial growth
(Peer reviewed; Journal article, 2023)Background Current tuberculosis treatment regimens could be improved by adjunct host-directed therapies (HDT) targeting host responses. We investigated the antimycobacterial capacity of macrophages from patients with ... -
Cylindrical cavity expansion approximations using different constitutive models for the target material
(Journal article; Peer reviewed, 2017)In this article, we investigate the results obtained using different constitutive models for the solution of the cylindrical cavity expansion problem under plane strain conditions. The cylindrical cavity expansion solutions ... -
Cytokine Network in Scrub Typhus: High Levels of Interleukin-8 Are Associated with Disease Severity and Mortality
(Journal article; Peer reviewed, 2014)Background: Scrub typhus, caused by Orientia tsutsugamushi, is endemic in the Asia-Pacific region. Mortality is high if untreated, and even with treatment as high as 10–20%, further knowledge of the immune response during ... -
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
(Peer reviewed; Journal article, 2023)Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab ... -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
(Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ...