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Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study
(Peer reviewed; Journal article, 2022)Background Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ... -
Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis
(Peer reviewed; Journal article, 2020)Introduction: Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; however, its use in ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Peer reviewed; Journal article, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Peer reviewed; Journal article, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications
(Peer reviewed; Journal article, 2024)Background A considerable inter-individual variability has been reported in the relationship between methadone doses applied and serum concentrations achieved in methadone maintenance treatment. However, the underlying ... -
Methane activation on bimetallic catalysts: properties and functions of surface Ni-Ag alloy
(Peer reviewed; Journal article, 2019)The paper presents a fundamental study of the properties and functions of well‐defined Ni−Ag surface alloys in methane decomposition and steam reforming, aiming at providing a better understanding of the principle for ... -
Methane monooxygenases: central enzymes in methanotrophy with promising biotechnological applications
(Peer reviewed; Journal article, 2021)Worldwide, the use of methane is limited to generating power, electricity, heating, and for production of chemicals. We believe this valuable gas can be employed more widely. Here we review the possibility of using methane ... -
Methane slip from gas fuelled ships: a comprehensive summary based on measurement data
(Journal article; Peer reviewed, 2018)Strict NO x emission regulations set for marine vessels by Tier III standard make ship owners/operators finding new efficient methods fulfilling these requirements. Utilization of LNG as main fuel at the moment is one of ... -
Methanol as a carbon substrate in the bio-economy: metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals
(Journal article; Peer reviewed, 2017)Bacteria are widely used as cell factories for production of enzymes and chemicals, mostly from sugars. Methylotrophic bacteria can utilize the one-carbon compound methanol as sole carbon source for growth, and metabolic ... -
Methanol-based acetoin production by genetically engineered Bacillus methanolicus
(Journal article; Peer reviewed, 2019)Methanol is an attractive alternative non-food feedstock for industrial fermentations that can be used instead of sugar-based raw materials. Here, the thermophilic and methylotrophic bacterium Bacillus methanolicus MGA3 ... -
Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains
(Journal article; Peer reviewed, 2015)Methanol is regarded as an attractive substrate for biotechnological production of value-added bulk products, such as amino acids and polyamines. In the present study, the methylotrophic and thermophilic bacterium Bacillus ... -
Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains
(Journal article; Peer reviewed, 2017)The use of methanol as a carbon source for biotechnological processes has recently attracted great interest due to relatively low price, high abundance, high purity of methanol, and the fact that it is a non-food raw ... -
Methanol-essential growth of corynebacterium glutamicum: Adaptive laboratory evolution overcomes limitation due to methanethiol assimilation pathway
(Peer reviewed; Journal article, 2020)Methanol is a sustainable substrate for biotechnology. In addition to natural methylotrophs, metabolic engineering has gained attention for transfer of methylotrophy. Here, we engineered Corynebacterium glutamicum for ... -
Method Development Progress in Genetic Engineering of Thraustochytrids
(Peer reviewed; Journal article, 2021)Thraustochytrids are unicellular, heterotrophic marine eukaryotes. Some species are known to store surplus carbon as intracellular lipids, and these also contain the long-chain polyunsaturated fatty acid docosahexaenoic ... -
Method for consistent along-track sharpness in a push-broom imaging system
(Journal article; Peer reviewed, 2023)The along track spatial resolution in push broom imaging systems depends on platform parameters and imaging settings. This paper present a method for achieving a consistent spatial resolution for varying exposure times. ... -
Method for Designing Semantic Annotation of Sepsis Signs in Clinical Text
(Chapter, 2023)Annotated clinical text corpora are essential for machine learning studies that model and predict care processes and disease progression. However, few studies describe the necessary experimental design of the annotation ... -
A method for determining the ductile damage parameters of high strength steels and weld metal
(Peer reviewed; Journal article, 2023)The microvoid based Gurson-Tvergaard-Needleman (GTN) model is a powerful tool for predicting ductile fracture behavior, and application of such model to steels and welds needs the identification of microvoid related damage ... -
A Method for Enterprise Architecture Model Slicing
(Peer reviewed; Journal article, 2022)Enterprise Architecture (EA) has been applied widely in industry as it brings substantial benefits to ease communication and improve business-IT alignment. However, due to its high complexity and cost, EA still plays a ... -
A method for generating complete EV charging datasets and analysis of residential charging behaviour in a large Norwegian case study
(Peer reviewed; Journal article, 2023)Electric vehicles (EVs) are part of the solution to achieve global carbon emissions reduction targets, and the number of EVs is increasing worldwide. Increased demand for EV charging can challenge the grid capacity of power ... -
Method for mean-line design and performance prediction of one-stage axial turbines
(Chapter, 2022)Today, expanders for Organic Rankine Cycles (ORC) are either inefficient or expensive. One reason for this is that expanders of power conversion systems usually operate under different conditions over an annual perspective. ...