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Functional Bowel Disorders Are Associated with a Central Immune Activation
(Journal article; Peer reviewed, 2017)Background. Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between ... -
Functional Brain Hyperactivations Are Linked to an Electrophysiological Measure of Slow Interhemispheric Transfer Time after Pediatric Moderate/Severe Traumatic Brain Injury
(Peer reviewed; Journal article, 2020)Increased task-related blood oxygen level dependent (BOLD) activation is commonly observed in functional magnetic resonance imaging (fMRI) studies of moderate/severe traumatic brain injury (msTBI), but the functional ... -
Functional Broadcast Repair of Multiple Partial Failures in Wireless Distributed Storage Systems
(Peer reviewed; Journal article, 2021)We consider a distributed storage system with n nodes, where a user can recover the stored file from any k nodes, and study the problem of repairing r partially failed nodes. We consider broadcast repair , that is, d ... -
Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates
(Journal article; Peer reviewed, 2023)Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that use O2 or H2O2 to oxidatively cleave glycosidic bonds. LPMOs are prevalent in nature, and the functional variation among these enzymes is a topic of ... -
Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment.
(Journal article; Peer reviewed, 2019) -
Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family
(Peer reviewed; Journal article, 2020)Bacterial alginate initially consists of 1-4-linked beta-D-mannuronic acid residues (M) which can be later epimerized to alpha-L-guluronic acid (G). The family of AlgE mannuronan C-5-epimerases from Azotobacter vinelandii ... -
Functional connectivity in human auditory networks and the origins of variation in the transmission of musical systems
(Journal article; Peer reviewed, 2019)Music producers, whether original composers or performers, vary in their ability to acquire and faithfully transmit music. This form of variation may serve as a mechanism for the emergence of new traits in musical systems. ... -
The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium
(Peer reviewed; Journal article, 2023)Current knowledge about functional connectivity in obsessive-compulsive disorder (OCD) is based on small-scale studies, limiting the generalizability of results. Moreover, the majority of studies have focused only on ... -
Functional dissection of inherited non-coding variation influencing multiple myeloma risk
(Peer reviewed; Journal article, 2022)Thousands of non-coding variants have been associated with increased risk of human diseases, yet the causal variants and their mechanisms-of-action remain obscure. In an integrative study combining massively parallel ... -
Functional diversity along the transverse axis of hippocampal area CA1
(Journal article; Peer reviewed, 2014)Decades of neuroscience research have shed lights on the hippocampus as a key structure for the formation of episodic memory. The hippocampus is divided into distinct subfields – CA1, CA2 and CA3. Whereas accumulating ... -
Functional electronic inversion layers at ferroelectric domain walls
(Journal article; Peer reviewed, 2017)Ferroelectric domain walls hold great promise as functional two-dimensional materials because of their unusual electronic properties. Particularly intriguing are the so-called charged walls where a polarity mismatch causes ... -
Functional Exploration of the Polysaccharide Lyase Family PL6
(Journal article; Peer reviewed, 2016)Alginate, the main cell-wall polysaccharide of brown algae, is composed of two residues: mannuronic acid (M-residues) and, its C5-epimer, guluronic acid (G-residues). Alginate lyases define a class of enzymes that cleave ... -
Functional group contributions to carbon fluxes in arctic-alpine ecosystems
(Journal article; Peer reviewed, 2019)Ongoing responses to climate change in arctic-alpine ecosystems, including the increasing dominance of deciduous shrubs, involve major shifts in plant functional group composition. Because rates of photosynthesis and ... -
Functional map of the macroglomerular complex of male Helicoverpa armigera
(Peer reviewed; Journal article, 2022)The mechanism of sex pheromone reception in the male cotton bollworm Helicoverpa armigera has been extensively studied because it has become an important model system for understanding insect olfaction. However, the pathways ... -
Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks
(Peer reviewed; Journal article, 2016)The generation of human neural tissue-like 3D structures holds great promise for disease modeling, drug discovery and regenerative medicine strategies. Promoting the establishment of complex cell-cell interactions, 3D ... -
Functional network topography of the medial entorhinal cortex
(Journal article; Peer reviewed, 2022)The medial entorhinal cortex (MEC) creates a map of local space,based on thefiring patterns of grid, head-direction (HD), border,and object-vector (OV) cells. How these cell types are organizedanatomically is debated. ... -
Functional organization of the hippocampal longitudinal axis
(Journal article; Peer reviewed, 2014)The precise functional role of the hippocampus remains a topic of much debate. The dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and spatial navigation and the ventral (or anterior) ... -
Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study
(Journal article; Peer reviewed, 2018)Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ... -
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
(Peer reviewed; Journal article, 2022)Functional precision medicine is a new, emerging area that can guide cancer treatment by capturing information from direct perturbations of tumor-derived, living cells, such as by drug sensitivity screening. Precision ... -
Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving
(Peer reviewed; Journal article, 2021)Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ...