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    • Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993-2011: an observational study 

      Askim, Åsa Susanne; Mehl, Arne; Paulsen, Julie; DeWan, Andrew T.; VESTRHEIM, DIDRIK FRIMANN; Åsvold, Bjørn Olav; Damås, Jan Kristian; Solligård, Erik (Journal article; Peer reviewed, 2016)
      Background: Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. There are however few longitudinal studies on the changes in case fatality rate of IPD in recent years. ...

    • Epidemiology and outcome of Staphylococcus aureusbloodstream infection and sepsis in a Norwegian county 1996–2011: an observational study 

      Paulsen, Julie; Mehl, Arne; Askim, Åsa Susanne; Solligård, Erik; Åsvold, Bjørn Olav; Damås, Jan Kristian (Journal article; Peer reviewed, 2015)
      Background: Staphylococcus aureus is one of the most common and lethal causes of bloodstream infection and the incidence is increasing. We carried out a prospective observational study of patients with Staphylococcus ...

    • Epidemiology and practice variations of shunt surgery for hydrocephalus: a nationwide registry-based study 

      Mansoor, Nadia; Gulati, Sasha; Fredriksli, Oddrun Anita; Salvesen, Øyvind Olav; Solheim, Ole Skeidsvoll (Peer reviewed; Journal article, 2023)
      OBJECTIVE Indications for surgical treatment of hydrocephalus (HC) can vary across centers. The authors sought to investigate the frequencies of surgically treated HC disorders and to study variations in the practice ...

    • Epidemiology and prevention of oesophageal adenocarcinoma 

      Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022)
      Oesophageal adenocarcinoma (OAC) develops from columnar metaplasia of the distal oesophagus, Barrett’s oesophagus (BO), secondary to chronic gastro-oesophageal reflux disease (GORD). In the present review, the stepwise ...

    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Peer reviewed; Journal article, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...

    • Epidemiology of diagnosed cluster headache in Norway 

      Vidal, Joan Crespi; Gulati, Sasha; Salvesen, Øyvind; Bratbak, Daniel Fossum; Dodick, David W; Matharu, Manjit Singh; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2022)
      Background: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We ...

    • The Epidemiology of Insomnia and Sleep Duration Across Mental and Physical Health: The SHoT Study 

      Sivertsen, Børge; Hysing, Mari; Harvey, Allison G.; Petrie, Keith J. (Peer reviewed; Journal article, 2021)
      Objective: Numerous epidemiological studies have been conducted to examine the prevalence and comorbidities of insomnia and document sleep duration, but a common limitation in many studies is the lack of use of agreed-upon ...

    • Epidemiology of paediatric trauma in Norway: a single-trauma centre observational study 

      Nesje, Eirik; Valøy, Nadine Nalini; Krüger, Andreas; Uleberg, Oddvar (Journal article; Peer reviewed, 2019)
      BACKGROUND: Trauma is a major cause of mortality and morbidity in children globally. The burden of injury shows substantial geographical differences, with a significant mortality reduction in children in Norway during the ...

    • Epidermal Gland Inspired Self-Repairing Slippery Lubricant-Infused Porous Coatings with Durable Low Ice Adhesion 

      Li, Tong; Zhuo, Yizhi; Håkonsen, Verner; Rønneberg, Sigrid; He, Jianying; Zhang, Zhiliang (Journal article; Peer reviewed, 2019)
      The limited durability of slippery lubricant-infused porous surfaces (SLIPS) restricts their practical applications. Inspired by the epidermal glands of skins, we developed a facile approach to durable SLIPS with gland-like ...

    • Epidurals during normal labour and birth — Midwives’ attitudes and experiences 

      Aune, Ingvild; Brøtmet, Siri; Grytskog, Katrine Heggem; Sperstad, Eldri Bakken (Peer reviewed; Journal article, 2020)
      Background Midwives have their own beliefs and values regarding pain during childbirth. Their preferences concerning labour pain management may influence women’s choices. Aim To gain a deeper understanding of midwives’ ...

    • EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes 

      Marakulina, Daria; Vorontsov, Ilya E.; Kulakovskiy, Ivan V.; Lennartsson, Andreas; Drabløs, Finn Sverre; Medvedeva, Yulia A. (Journal article; Peer reviewed, 2023)

    • EpiFactors: A comprehensive database of human epigenetic factors and complexes 

      Medvedeva, Yulia; Lennartsson, Andreas; Ehsani, Rezvan; Kulakovskiy, Ivan; Vorontsov, Ilya E; Panahandeh, Pouda; Khimulya, Grigory; Kasukawa, Takeya; Drabløs, Finn (Peer reviewed; Journal article, 2015)
      Epigenetics refers to stable and long-term alterations of cellular traits that are not caused by changes in the DNA sequence per se . Rather, covalent modifications of DNA and histones affect gene expression and genome ...

    • Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth 

      Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2021)
      In vertebrates, the somatotropic axis comprising the pituitary gland, liver and muscle plays a major role in myogenesis. Its output in terms of muscle growth is highly affected by nutritional and environmental cues, and ...

    • Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking 

      Petrovic, Dusan; Bodinier, Barbara; Dagnino, Sonia; Whitaker, Matthew; Karimi, Maryam; Campanella, Gianluca; Nøst, Therese Haugdahl; Polidoro, Silvia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Lund, Eiliv; Dugué, Pierre-Antoine; Giles, Graham G; Severi, Gianluca; Southey, Melissa; Vineis, Paolo; Stringhini, Silvia; Bochud, Murielle; Sandanger, Torkjel M; Vermeulen, Roel CH; Guida, Florence; Chadeau-Hyam, Marc (Peer reviewed; Journal article, 2022)
      Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and ...

    • Epigenetic modulation of stem cells in neurodevelopment: The role of methylation and acetylation 

      Podobinska, Martyna; Szablowska-Gadomska, Ilona; Augustyniak, Justyna; Sandvig, Ioanna; Sandvig, Axel; Buzanska, Leonora (Journal article; Peer reviewed, 2017)
      The coordinated development of the nervous system requires fidelity in the expression of specific genes determining the different neural cell phenotypes. Stem cell fate decisions during neurodevelopment are strictly ...

    • Epigenetics in the primary and secondary prevention of cardiovascular disease: influence of exercise and nutrition 

      Gevaert, Andreas B.; Wood, Nathaneal; Boen, Jente R A; Davos, Constantinos H.; Hansen, Dominique; Hanssen, Henner; Krenning, Guido; Moholdt, Trine; Osto, Elena; Paneni, Francesco; Pedretti, Roberto F E; Plösch, Torsten; Simonenko, Maria; Bowen, T Scott (Peer reviewed; Journal article, 2022)
      Increasing evidence links changes in epigenetic systems, such as DNA methylation, histone modification, and non-coding RNA expression, to the occurrence of cardiovascular disease (CVD). These epigenetic modifications can ...

    • Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain 

      Opsahl, J. O.; Fragoso-Bargas, N.; Lee, Y.; Carlsen, E. Ø.; Lekanova, N.; Qvigstad, E.; Sletner, L.; Jenum, A. K.; Lee-Ødegård, S.; Prasad, R. B.; Birkeland, K. I.; Moen, G-H.; Sommer, C. (Peer reviewed; Journal article, 2024)
      Objectives We aimed to discover CpG sites with differential DNA methylation in peripheral blood leukocytes associated with body mass index (BMI) in pregnancy and gestational weight gain (GWG) in women of European and ...

    • Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes 

      Fragoso-Bargas, Nicolas; Page, Christian Magnus; Joubert, Bonnie R.; London, Stephanie J.; Lee-Ødegård, Sindre; Opsahl, Julia Onsrud; Sletner, Line; Jenum, Anne Karen; Qvigstad, Elisabeth; Prasad, Rashmi B.; Moen, Gunn-Helen Øiseth; Birkeland, Kåre Inge; Sommer, Christine (Peer reviewed; Journal article, 2023)
      Aim: To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. Methods: Cross-ancestry (Europeans = 302, South Asians = 161) and ancestry-specific EWAS in the EPIPREG cohort were performed, ...

    • Epigenome-wide methylation differences in a group of lean and obese women – A HUNT Study 

      Kvaløy, Kirsti; Page, Christian; Holmen, Turid Lingaas (Journal article; Peer reviewed, 2018)
      Knowledge of epigenetically regulated biomarkers linked to obesity development is still scarce. Improving molecular understanding of the involved factors and pathways would improve obesity phenotype characterization and ...

    • Epilepsy and other seizure disorders in acute psychiatric inpatients 

      Nakken, Erlend Iversen; Grinde, Frithjof; Vaaler, Arne; Drange, Ole Kristian; Brodtkorb, Eylert; Sæther, Sverre Georg (Peer reviewed; Journal article, 2021)
      Background: It is well known that patients with epilepsy have a high rate of psychiatric comorbidity. However, studies exploring epilepsy in psychiatric cohorts are scarce. The aim of this study was to examine the prevalence ...