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Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
(Peer reviewed; Journal article, 2020)Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate ... -
A genetic programming approach for searching on nearest neighbors graphs
(Peer reviewed; Journal article, 2022)Nearest neighbors graphs have gained a lot of attention from the information retrieval community since they were demonstrated to outperform classical approaches in the task of approximate nearest neighbor search. These ... -
Genetic rescue of an endangered domestic animal through outcrossing with closely related breeds: A case study of the Norwegian Lundehund
(Journal article; Peer reviewed, 2017)Genetic rescue, outcrossing with individuals from a related population, is used to augment genetic diversity in populations threatened by severe inbreeding and extinction. The endangered Norwegian Lundehund dog underwent ... -
Genetic Rescue of the Highly Inbred Norwegian Lundehund
(Journal article; Peer reviewed, 2022)Augmenting the genetic diversity of small, inbred populations by the introduction of new individuals is often termed “genetic rescue“. An example is the Norwegian Lundehund, a small spitz dog with inbreeding-related health ... -
Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study
(Peer reviewed; Journal article, 2020)Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ... -
Genetic similarity between relatives provides evidence on the presence and history of assortative mating
(Journal article; Peer reviewed, 2024)Assortative mating – the non-random mating of individuals with similar traits – is known to increase trait-specific genetic variance and genetic similarity between relatives. However, empirical evidence is limited for many ... -
Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache
(Peer reviewed; Journal article, 2021)Objective Identifying common genetic variants that confer genetic risk for cluster headache. Methods We conducted a case–control study in the Dutch Leiden University Cluster headache neuro-Analysis program (LUCA) study ... -
Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae
(Journal article; Peer reviewed, 2018)Although Escherichia coli and Bacillus subtilis are the most prominent bacterial hosts for recombinant protein production by far, additional species are being explored as alternatives for production of difficult-to-express ... -
The genetic underpinnings of right-wing authoritarianism and social dominance orientation explain political attitudes beyond Big Five personality
(Journal article; Peer reviewed, 2024)Objective: Political attitudes are predicted by the key ideological variables of right-wing authoritarianism (RWA) and social dominance orientation (SDO), as well as some of the Big Five personality traits. Past research ... -
Genetic variability and structure of the water vole Arvicola amphibius across four metapopulations in northern Norway
(Journal article; Peer reviewed, 2013)Water vole Arvicola amphibius populations have recently experienced severe decline in several European countries as a consequence of both reduction in suitable habitat and the establishment of the alien predator American ... -
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
(Peer reviewed; Journal article, 2021)Selective serotonin reuptake inhibitors (SSRIs) are prescribed both to patients with schizophrenia and bipolar disorder. Previous studies have shown associations between SSRI treatment and cardiometabolic alterations. The ... -
Genetic variants related to physical activity or sedentary behaviour: a systematic review
(Peer reviewed; Journal article, 2021)Background Research shows that part of the variation in physical activity and sedentary behaviour may be explained by genetic factors. Identifying genetic variants associated with physical activity and sedentary behaviour ... -
Genetic variation and cognitive dysfunction in opioid-treated patients with cancer
(Peer reviewed; Journal article, 2016)Background and purpose The effects of single‐nucleotide polymorphisms (SNPs) on the cognitive function of opioid‐treated patients with cancer until now have not been explored, but they could potentially be related to ... -
Genetic variation and structure of house sparrow populations: is there an island effect?
(Journal article; Peer reviewed, 2013)Population genetic structure and intrapopulation levels of genetic variation have important implications for population dynamics and evolutionary processes. Habitat fragmentation is one of the major threats to biodiversity. ... -
Genetic Variation in Metabolic Rate and Correlations with Other Energy Budget Components and Life History in Daphnia magna
(Peer reviewed; Journal article, 2019)Much is known about the genetic variance in certain components of metabolism, most notably resting and maximum metabolic rate. This is in stark contrast to the lack of information on genetic variance in the metabolic rate ... -
Genetic Variation Of Platelet Glycoprotein VI And The Risk Of Venous Thromboembolism
(Journal article, 2019) -
Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium
(Journal article; Peer reviewed, 2019)Members of the Mycobacterium avium complex (MAC) are characterized as nontuberculosis mycobacteria and are pathogenic mainly in immunocompromised individuals. MAC strains show a wide genetic variability, and there is growing ... -
Genetically controlled mtDNA deletions prevent ROS damage by arresting oxidative phosphorylation
(Journal article; Peer reviewed, 2022) -
Genetically predicted cortisol levels and risk of venous thromboembolism
(Peer reviewed; Journal article, 2022)Introduction In observational studies, venous thromboembolism (VTE) has been associated with Cushing’s syndrome and with persistent mental stress, two conditions associated with higher cortisol levels. However, it remains ...