Browsing Publikasjoner fra CRIStin - NTNU by Title

Now showing items 6405-6424 of 37637

    • Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood 

      Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik; Barratt-Due, Andreas (Journal article; Peer reviewed, 2019)
      Heme is a critical danger molecule liberated from hemeproteins in various conditions, including from hemoglobin in hemolytic diseases. Heme may cause thromboinflammatory damage by activating inflammatory and hemostatic ...

    • Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function 

      Pischke, Søren Erik; Gustavsen, Alice; Orrem, HL; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2017)
      Inhibition of complement factor 5 (C5) reduced myocardial infarction in animal studies, while no benefit was found in clinical studies. Due to lack of cross-reactivity of clinically used C5 antibodies, different inhibitors ...

    • Complement factors B, D, C3bBbP and risk of future venous thromboembolism 

      Skjeflo, Espen Waage; Evensen, Line Holtet; Jensen, Søren Beck; Latysheva, Nadezhda; Michelsen, Annika Elisabet; Ueland, Thor; Brækkan, Sigrid Kufaas; Hindberg, Kristian Dalsbø; Snir, Omri; Mollnes, Tom Eirik; Hansen, John Bjarne (Peer reviewed; Journal article, 2023)
      The complement system appears to be involved in the pathogenesis of venous thromboembolism (VTE). We investigated the association of complement factors (CF) B, D, and the alternative pathway convertase, C3bBbP, measured ...

    • Complement in clinical medicine: Clinical trials, case reports and therapy monitoring 

      Ricklin, Daniel; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2017)
      Research during past decades made it evident that complement is involved in more tasks than fighting infections, but has important roles in other immune surveillance and housekeeping functions. If the balance between ...

    • Complement in sepsis — when science meets clinics 

      Mollnes, Tom Eirik; Huber-Lang, Markus (Peer reviewed; Journal article, 2020)
      Sepsis as life‐threatening organ dysfunction caused by microorganisms represents a dreadful challenge for the immune system. The role of the complement system as major column of innate immunity has been extensively studied ...

    • Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys 

      Jager, Neeltina M.; Venema, Leonie H.; Arykbaeva, Asel S.; Meter-Arkema, Anita H.; Ottens, Petra J.; van Kooten, Cees; Mollnes, Tom Eirik; Alwayn, Ian P. J.; Leuvenink, Henri G. D.; Pischke, Soeren (Peer reviewed; Journal article, 2022)
      Background: The gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected ...

    • Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: A longitudinal study of the Nordic JIA cohort 

      Glerup, Mia; Thiel, Steffen; Rypdal, Veronika Gjertsen; Arnstad, Ellen Dalen; Ekelund, Maria; Peltoniemi, Suvi; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan; Fasth, Anders; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels (Journal article; Peer reviewed, 2019)
      Background To determine the serum levels of the lectin pathway proteins early in the disease course and 17 years after disease onset and to correlate the protein levels to markers of disease activity in participants ...

    • Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically 

      Thomas, Anub Mathew; Chaban, Viktoriia; Pischke, Soeren; Orrem, Hilde Lang; Bosnes, Vidar; Sunde, Kjetil; Seljeflot, Ingebjørg; Lundqvist, Christofer; Nakstad, Espen Rostrup; Andersen, Geir Øystein; Schjalm, Camilla; Mollnes, Tom Eirik; Barratt-Due, Andreas (Peer reviewed; Journal article, 2021)
      Background Complement activation plays an important pathogenic role in numerous diseases. The ratio between an activation product and its parent protein is suggested to be more sensitive to detect complement activation ...

    • Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism 

      Arbore, Giuseppina; West, Erin; Rahman, Jubayer; Le Friec, Gaelle; Niyonzima, Nathalie; Mehdi, Pirooznia; Ilker, Tunc; Polychronis, Pavlidis; Nicholas, Powell; Li, Yuesheng; Liu, Poching; Servais, Aude; Couzi, Lionel; Fremeaux-Bacchi, Veronique; Placais, Leo; Ferraro, Alastair; Walsh, Patrick R.; Kavanagh, David; Afzali, Behdad; Lavender, Paul; Lachmann, Helen J.; Kemper, Claudia (Journal article; Peer reviewed, 2018)
      The induction of human CD4+ Th1 cells requires autocrine stimulation of the complement receptor CD46 in direct crosstalk with a CD4+ T cell-intrinsic NLRP3 inflammasome. However, it is unclear whether human cytotoxic CD8+ ...

    • Complementarity of Data-Driven and Simulation Modeling Based on the Power Plant Model of the Offshore Vessel 

      Swider, Anna; Skjong, Stian; Pedersen, Eilif (Chapter; Peer reviewed, 2017)
      Nowadays, there are more ships equipped with on-board monitoring systems and vessels with many sensors are becoming a standard. Available measurements can be employed for system optimization which play an important role ...

    • The complementarity of formative intervention research, action research and action learning 

      Postholm, May Britt (Peer reviewed; Journal article, 2020)
      Background This article focuses on the complementarity between formative interventions research conducted within the framework of cultural historical activity theory, action research and learning, as well as how this ...

    • The complementary effect of lean manufacturing and digitalisation on operational performance 

      Buer, Sven-Vegard; Semini, Marco; Strandhagen, Jan Ola; Sgarbossa, Fabio (Peer reviewed; Journal article, 2020)
      The most recent trend manufacturers have embraced to seek operational performance improvements is the use of a wide range of digital technologies typically associated with Industry 4.0. However, few studies have investigated ...

    • Complete embolization of a mechanical aortic valve during trail running - a case report with a lucky ending 

      Dalen, Håvard; Graven, Torbjørn; Slagsvold, Katrine Hordnes; Krogstad, Lars Erik Berg; Saxhaug, Lars Mølgaard; Tannvik, Tomas Dybos; Holte, Espen; Nordhaug, Dag Ole; Karlsen, Øystein; Thorstensen, Anders; Wahba, Alexander; Winnerkvist, Anders (Peer reviewed; Journal article, 2022)
      Background Complete embolization of a prosthetic heart valve is extremely rare and dangerous. This case reports a total embolization of a mechanical aortic valve and contributes to the literature regarding the diagnostic ...

    • Complete Evaluation of Cell Mixing and Hydrodynamic Performance of Thin-Layer Cascade Reactor 

      Akhtar, Shehnaz; Ali, Haider; Park, Cheol Woo (Peer reviewed; Journal article, 2020)
      Microalgae are a great source of food and supplements as well as a potential source for the production of biofuels. However, the operational cost must be reduced to allow viable productions of bulk chemicals such as biofuels ...

    • The complete genome sequence of Listeria monocytogenes strain S2542 and expression of selected genes under high-pressure processing 

      Duru, Ilhan Cem; Bucur, Florentina Ionela; Andreevskaya, Margarita; Ylinen, Anne; Crauwels, Peter; Grigore-Gurgu, Leontina; Nikparvar, Bahareh; Rode, Tone Mari; Laine, Pia; Paulin, Lars; Løvdal, Trond; Riedel, Christian U.; Bar, Nadav; Borda, Daniela; Nicolau, Anca Ioana; Auvinen, Petri (Peer reviewed; Journal article, 2021)
      Objectives The study aims to generate the whole genome sequence of L. monocytogenes strain S2542 and to compare it to the genomes of strains RO15 and ScottA. In addition, we aimed to compare gene expression profiles of ...

    • Complete magnetic control over the superconducting thermoelectric effect 

      Ouassou, Jabir Ali; González-Ruano, César; Caso, Diego; Aliev, Farkhad G.; Linder, Jacob (Peer reviewed; Journal article, 2022)
      Giant thermoelectric effects are known to arise at the interface between superconductors and strongly polarized ferromagnets, enabling the construction of efficient thermoelectric generators. We predict that the thermopower ...

    • Completeness and correctness of cerebral palsy diagnoses in two health registers: implications for estimating prevalence 

      Hollung, Sandra Julsen; Vik, Torstein; Wiik, Robert; Bakken, Inger Johanne; Andersen, Guro Lillemoen (Journal article; Peer reviewed, 2017)
      Aim To assess completeness and correctness of cerebral palsy (CP) diagnoses in the Cerebral Palsy Register of Norway (CPRN) and the Norwegian Patient Register (NPR), and to estimate CP prevalence. Method Among 747 883 ...

    • Completion surgery vs. primary TME for early rectal cancer: a national study 

      Lossius, William J; Stornes, Tore; Myklebust, Tor Åge; Endreseth, Birger Henning; Wibe, Arne (Journal article; Peer reviewed, 2021)
      Purpose While local excision by transanal endoscopic microsurgery (TEM) or transanal minimally invasive surgery (TAMIS) is an option for low-risk early rectal cancers, inaccuracies in preoperative staging may be revealed ...

    • Complex accident scenarios modelled and analysed by Stochastic Petri Nets 

      Nyvlt, Ondrej; Haugen, Stein; Ferkl, Lukas (Journal article; Peer reviewed, 2015)
      This paper is focused on the usage of Petri nets for an effective modelling and simulation of complicated accident scenarios, where an order of events can vary and some events may occur anywhere in an event chain. These ...

    • Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform 

      Berges, Natalia; Nawaz, Meh Sameen; Dahl, Tuva Børresdatter; Hagen, Lars; Bjørås, Magnar; Lærdahl, Jon Kristen; Alseth, Ingrun (Journal article; Peer reviewed, 2019)
      Endonuclease V (ENDOV) is a ribonuclease with affinity for inosine which is the deamination product of adenosine. The genomes of most organisms, including human, encode ENDOV homologs, yet knowledge about in vivo functions ...