dc.contributor.author | Mikolic, Ana | |
dc.contributor.author | Polinder, Suzanne | |
dc.contributor.author | Steyerberg, Ewout W | |
dc.contributor.author | Retel Helmrich, Isabel | |
dc.contributor.author | Giacino, Joseph T. | |
dc.contributor.author | Maas, Andrew I.R. | |
dc.contributor.author | van der Naalt, Joukje | |
dc.contributor.author | Voormolen, Daphne | |
dc.contributor.author | von Steinbüchel, Nicole | |
dc.contributor.author | Wilson, Lindsay | |
dc.contributor.author | Lingsma, Hester F | |
dc.contributor.author | van Klaveren, David | |
dc.contributor.author | Andelic, Nada | |
dc.contributor.author | Andreassen, Lasse | |
dc.contributor.author | Anke, Audny | |
dc.contributor.author | Frisvold, Shirin | |
dc.contributor.author | Helseth, Eirik | |
dc.contributor.author | Røe, Cecilie | |
dc.contributor.author | Røise, Olav | |
dc.contributor.author | Skandsen, Toril | |
dc.contributor.author | Vik, Anne | |
dc.contributor.author | Åkerlund, Cecilia | |
dc.contributor.author | Amrein, Krisztina | |
dc.contributor.author | Antoni, Anna | |
dc.contributor.author | Audibert, Gerard | |
dc.contributor.author | Azouvi, Philippe | |
dc.contributor.author | Azzolini, Maria Luisa | |
dc.contributor.author | Bartels, Ronald | |
dc.contributor.author | Barzo, Pal | |
dc.contributor.author | Beauvais, Romuald | |
dc.contributor.author | Beer, Ronny | |
dc.contributor.author | Bellander, Bo-Michael | |
dc.contributor.author | Belli, Antonio | |
dc.contributor.author | Benali, Habib | |
dc.contributor.author | Berardino, Maurizio | |
dc.contributor.author | Beretta, Luigi | |
dc.contributor.author | Blaabjerg, Morten | |
dc.contributor.author | Bragge, Peter | |
dc.contributor.author | Brazinova, Alexandra | |
dc.contributor.author | Brinck, Vibeke | |
dc.contributor.author | Brooker, Joanne | |
dc.contributor.author | Brorsson, Camilla | |
dc.contributor.author | Buki, Andras | |
dc.contributor.author | Bullinger, Monika | |
dc.contributor.author | Cabeleira, Manuel | |
dc.contributor.author | Caccioppola, Alessio | |
dc.contributor.author | Calappi, Emiliana | |
dc.contributor.author | Calvi, Maria Rosa | |
dc.contributor.author | Cameron, Peter | |
dc.contributor.author | Lozano, Guillermo Carbayo | |
dc.contributor.author | Carbonara, Marco | |
dc.date.accessioned | 2021-02-22T10:50:48Z | |
dc.date.available | 2021-02-22T10:50:48Z | |
dc.date.created | 2021-02-09T14:53:51Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Journal of Neurotrauma. 2020, 38 (2), 196-209. | en_US |
dc.identifier.issn | 0897-7151 | |
dc.identifier.uri | https://hdl.handle.net/11250/2729468 | |
dc.description.abstract | The majority of traumatic brain injuries (TBIs) are categorized as mild, according to a baseline Glasgow Coma Scale (GCS) score of 13–15. Prognostic models that were developed to predict functional outcome and persistent post-concussive symptoms (PPCS) after mild TBI have rarely been externally validated. We aimed to externally validate models predicting 3–12-month Glasgow Outcome Scale Extended (GOSE) or PPCS in adults with mild TBI. We analyzed data from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) project, which included 2862 adults with mild TBI, with 6-month GOSE available for 2374 and Rivermead Post-Concussion Symptoms Questionnaire (RPQ) results available for 1605 participants. Model performance was evaluated based on calibration (graphically and characterized by slope and intercept) and discrimination (C-index). We validated five published models for 6-month GOSE and three for 6-month PPCS scores. The models used different cutoffs for outcome and some included symptoms measured 2 weeks post-injury. Discriminative ability varied substantially (C-index between 0.58 and 0.79). The models developed in the Corticosteroid Randomisation After Significant Head Injury (CRASH) trial for prediction of GOSE | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Mary Ann Liebert, Inc. | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Prediction of Global Functional Outcome and Post-Concussive Symptoms after Mild Traumatic Brain Injury: External Validation of Prognostic Models in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 196-209 | en_US |
dc.source.volume | 38 | en_US |
dc.source.journal | Journal of Neurotrauma | en_US |
dc.source.issue | 2 | en_US |
dc.identifier.doi | 10.1089/neu.2020.7074 | |
dc.identifier.cristin | 1888180 | |
dc.description.localcode | Ana Mikolic´ et al. 2020; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |