Optimization of SERS Sensing With Micro-Lensed Optical Fibers and Au Nano-Film
Milenko, Karolina Barbara; Fuglerud, Silje Skeide; Aksnes, Astrid; Ellingsen, Reinold; Hjelme, Dag Roar
Peer reviewed, Journal article
Published version
Åpne
Permanent lenke
https://hdl.handle.net/11250/2725710Utgivelsesdato
2020Metadata
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- Institutt for elektroniske systemer [2277]
- Publikasjoner fra CRIStin - NTNU [36890]
- St. Olavs hospital [2423]
Sammendrag
We present the fabrication and characterization of optical fiber reflection probes based on surface-enhanced Raman scattering (SERS) and micro-lensed multimode fibers. For the SERS substrate, a nano-sphere lithography method is used. Comparison of SERS measurements with three different fiber probe configurations is presented. The proposed optimized structure shows a five times increase in SERS signal for dried Rhodamine 6G (R6G) and two times for aqueous R6G in comparison to a standard reflection configuration. Measurements of different concentrations of R6G in a water solution with an limit of detection (LOD) equal to 10 -7 M are demonstrated.