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dc.contributor.authorAsante, Ernest O
dc.contributor.authorSun, Yi-Qian
dc.contributor.authorNilsen, Tom Ivar Lund
dc.contributor.authorÅsvold, Bjørn Olav
dc.contributor.authorSørgjerd, Elin Pettersen
dc.contributor.authorMai, Xiao-Mei
dc.identifier.citationBMJ Open.2019, 10 (3)en_US
dc.description.abstractObjective We aimed to examine relationship between hours lying down per day, as a proxy for sedentary behaviour and risk of diabetes in young and middle-aged adults, and to assess if leisure-time physical activity and body mass index (BMI) modified this relationship. Design A population-based prospective cohort study. Setting Nord-Trøndelag, Norway. Participants The cohort included 17 058 diabetes-free adults, at an age of 20–55 years in 1995–1997, who were followed-up to 2006–2008. Primary outcome measures Incident diabetes was defined by self-report of diabetes or non-fasting glucose levels greater than 11 mmol/L at the follow-up. Methods Multivariable logistic regression models were used to obtain OR with 95% CI for risk of diabetes by the categories of hours lying down (≤7, 8 and ≥9 hours/day). Results 362 individuals (2.1%) developed diabetes during an average of 11-year follow-up. Individuals who reported lying down ≥9 hours/day had an adjusted OR of 1.35 (95% CI 1.01 to 1.80) for incident diabetes compared with those lying down 8 hours/day. Lying down ≤7 hours/day was not associated with the risk of diabetes. In analysis stratified by physical activity, the ORs associated with lying down ≥9 hours/day were 1.41 (95% CI 1.05 to 1.90) and 0.90 (95% CI 0.23 to 3.55), respectively, among the less active and highly active individuals (pinteraction=0.048). There was little evidence that the association differed by BMI status (pinteraction=0.62). Conclusions Prolonged hours lying down per day was associated with an increased risk of diabetes in young and middle-aged adults. The positive association appeared to be modified by physical activity but not by BMI.en_US
dc.publisherBMJ Journalsen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.titleHours lying down per day, as a proxy for sedentary behaviour and risk of diabetes in young and middle-aged adults in Norway: an 11-year follow-up of the HUNT studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.source.journalBMJ Openen_US
dc.description.localcodeThis is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:

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Navngivelse-Ikkekommersiell 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse-Ikkekommersiell 4.0 Internasjonal