Vis enkel innførsel

dc.contributor.authorStenberg, Jonas
dc.contributor.authorHåberg, Asta
dc.contributor.authorFollestad, Turid
dc.contributor.authorOlsen, Alexander
dc.contributor.authorIverson, Grant L.
dc.contributor.authorTerry P., Douglas
dc.contributor.authorKarlsen, Rune Hatlestad
dc.contributor.authorSaksvik, Simen Berg
dc.contributor.authorKaraliute, Migle
dc.contributor.authorEk, John Andre Nebb
dc.contributor.authorSkandsen, Toril
dc.contributor.authorVik, Anne
dc.coverage.spatialª2019 by the American Congress of Rehabilitation Medicine. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.date.accessioned2020-03-23T16:15:57Z
dc.date.available2020-03-23T16:15:57Z
dc.date.created2019-12-23T13:27:21Z
dc.date.issued2019
dc.identifier.citationArchives of Physical Medicine and Rehabilitation. 2019, 101 (1), 72-80.en_US
dc.identifier.issn0003-9993
dc.identifier.urihttps://hdl.handle.net/11250/2648213
dc.description.abstractObjective To investigate whether cognitive reserve moderates differences in cognitive functioning between patients with mild traumatic brain injury (MTBI) and controls without MTBI and to examine whether patients with postconcussion syndrome have lower cognitive functioning than patients without postconcussion syndrome at 2 weeks and 3 months after injury. Design Trondheim MTBI follow-up study is a longitudinal controlled cohort study with cognitive assessments 2 weeks and 3 months after injury. Setting Recruitment at a level 1 trauma center and at a general practitioner-run, outpatient clinic. Participants Patients with MTBI (n=160) according to the World Health Organization criteria, trauma controls (n=71), and community controls (n=79) (N=310). Main Outcome Measures A cognitive composite score was used as outcome measure. The Vocabulary subtest was used as a proxy of cognitive reserve. Postconcussion syndrome diagnosis was assessed at 3 months with the British Columbia Postconcussion Symptom Inventory. Results Linear mixed models demonstrated that the effect of vocabulary scores on the cognitive composite scores was larger in patients with MTBI than in community controls at 2 weeks and at 3 months after injury (P=.001). Thus, group differences in the cognitive composite score varied as a function of vocabulary scores, with the biggest differences seen among participants with lower vocabulary scores. There were no significant differences in the cognitive composite score between patients with (n=29) and without (n=131) postconcussion syndrome at 2 weeks or 3 months after injury. Conclusion Cognitive reserve, but not postconcussion syndrome, was associated with cognitive outcome after MTBI. This supports the cognitive reserve hypothesis in the MTBI context and suggests that persons with low cognitive reserve are more vulnerable to reduced cognitive functioning if they sustain an MTBI.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titleCognitive Reserve Moderates Cognitive Outcome After Mild Traumatic Brain Injuryen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber72-80en_US
dc.source.volume101en_US
dc.source.journalArchives of Physical Medicine and Rehabilitationen_US
dc.source.issue1en_US
dc.identifier.doi10.1016/j.apmr.2019.08.477
dc.identifier.cristin1763759
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.fulltextoriginal
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal