Vis enkel innførsel

dc.contributor.authorThe Gene Ontology, Consortium
dc.contributor.authorthat, includes
dc.contributor.authorAcencio, Marcio Luis
dc.contributor.authorLægreid, Astrid
dc.contributor.authorKuiper, Martin
dc.contributor.authoramong, others
dc.date.accessioned2019-09-03T06:16:39Z
dc.date.available2019-09-03T06:16:39Z
dc.date.created2018-11-14T13:19:08Z
dc.date.issued2019
dc.identifier.citationNucleic Acids Research. 2019, 47, D1 (D330–D338)nb_NO
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/11250/2612111
dc.description.abstractThe Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products. Founded in 1998, GO has become widely adopted in the life sciences, and its contents are under continual improvement, both in quantity and in quality. Here, we report the major developments of the GO resource during the past two years. Each monthly release of the GO resource is now packaged and given a unique identifier (DOI), enabling GO-based analyses on a specific release to be reproduced in the future. The molecular function ontology has been refactored to better represent the overall activities of gene products, with a focus on transcription regulator activities. Quality assurance efforts have been ramped up to address potentially out-of-date or inaccurate annotations. New evidence codes for high-throughput experiments now enable users to filter out annotations obtained from these sources. GO-CAM, a new framework for representing gene function that is more expressive than standard GO annotations, has been released, and users can now explore the growing repository of these models. We also provide the ‘GO ribbon’ widget for visualizing GO annotations to a gene; the widget can be easily embedded in any web page.nb_NO
dc.language.isoengnb_NO
dc.publisherOxford Academicnb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleThe Gene Ontology Resource: 20 years and still GOing strong.nb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.journalNucleic Acids Researchnb_NO
dc.source.issuegky1055nb_NO
dc.identifier.doi10.1093/nar/gky1055
dc.identifier.cristin1630481
dc.relation.projectNorges forskningsråd: 247727nb_NO
dc.description.localcodeThis is an open access article distributed under the terms of the Creative Commons CC BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.nb_NO
cristin.unitcode194,65,15,0
cristin.unitcode194,66,10,0
cristin.unitnameInstitutt for klinisk og molekylær medisin
cristin.unitnameInstitutt for biologi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Navngivelse 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Navngivelse 4.0 Internasjonal