St. Olavs hospital: Nye registreringer
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Post mortem tissue distribution of quetiapine in forensic autopsies
(Peer reviewed; Journal article, 2020)The antipsychotic drug quetiapine is widely used, and increasingly prescribed off-label. Furthermore, quetiapine use has been linked to increased mortality rates, most likely due to a range of cardiovascular and metabolic ... -
Within family Mendelian randomization studies
(Peer reviewed; Journal article, 2019)Mendelian randomization (MR) is increasingly used to make causal inferences in a wide range of fields, from drug development to etiologic studies. Causal inference in MR is possible because of the process of genetic ... -
Barriers and facilitators to cervical cancer screening in Nepal: A qualitative study
(Peer reviewed; Journal article, 2019)Objectives Despite being preventable, cervical cancer remains the most common cancer among women in Nepal, a country where there is no nationwide screening programme. Hence, the objective was to investigate and better ... -
Socioeconomic factors affect treatment delivery for patients with low grade glioma: a Swedish population-based study
(Peer reviewed; Journal article, 2019)Background Despite aspirations to achieve equality in healthcare we know that socioeconomic differences exist and may affect treatment and patient outcome, also in serious diseases such as cancer. We investigated ... -
Exploring use of activity monitors for patients with obesity during weight-loss treatment - a qualitative study
(Peer reviewed; Journal article, 2021)Background Obesity is a major health concern in western countries. In Norway, patients with obesity can attend weight-loss programmes, which focus on changes in dietary and physical activity habits. Use of self-monitoring ... -
Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study
(Peer reviewed; Journal article, 2021)Background: Having accurate, up-to-date information on the epidemiology of mild cognitive impairment (MCI) and dementia is imperative. Objective: To determine the prevalence of MCI and dementia in Norway using data ... -
Antibiotic-loaded bone cement in prevention of periprosthetic joint infections in primary total knee arthroplasty: A register-based multicentre randomised controlled non-inferiority trial (ALBA trial)
(Peer reviewed; Journal article, 2021)Introduction The current evidence on the efficacy of antibiotic-loaded bone cement (ALBC) in reducing the risk of periprosthetic joint infections (PJI) after primary joint reconstruction is insufficient. In several European ... -
Nephronectin as a matrix effector in cancer
(Peer reviewed; Journal article, 2021)The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five ... -
Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer
(Peer reviewed; Journal article, 2021)Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with ... -
Inflammatory diseases among Norwegian LRRK2 mutation carriers. A 15-years follow-up of a cohort
(Peer reviewed; Journal article, 2021)The first families with LRRK2 related Parkinson’s disease (PD) were presented around 15 years ago and numerous papers have described the characteristics of the LRRK2 phenotype. The prevalence of autosomal dominant PD varies ... -
The pen, the receiver and the pump: Exploring young children's experiences of having a parent with type 1 diabetes
(Peer reviewed; Journal article, 2021)In this article, we explore young children's experiences of having a parent with type 1 diabetes (T1D). In our research we found that the children's knowledge about T1D was not age related, and that some had more in‐depth ... -
EACVI survey on investigations and imaging modalities in chronic coronary syndromes
(Peer reviewed; Journal article, 2021)Aims The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey to evaluate current practice for the assessment and management of patients with suspected and ... -
The impact of authors’ medical specialty on publication patterns and published results of adjuvant radiotherapy for WHO grade 2 meningiomas—a systematic review
(Peer reviewed; Journal article, 2021)Background The role of adjuvant radiotherapy after gross total resection (GTR) of WHO grade 2 meningioma remains unclear, and conflicting results have been published. We hypothesized that authors’ medical specialties could ... -
Is pituitary MRI screening necessary in cluster headache?
(Peer reviewed; Journal article, 2021)Objective To determine the prevalence and clinical predictors of pituitary adenomas in cluster headache patients, in order to determine the necessity of performing dedicated pituitary magnetic resonance imaging in patients ... -
Initial experience with positron emission tomography/computed tomography in addition to computed tomography and magnetic resonance imaging in preoperative risk assessment of endometrial cancer patients
(Peer reviewed; Journal article, 2021)Objective: Improved preoperative evaluation of lymph node status could potentially replace lymphadenectomy in women with endometrial cancer. PET/CT was routinely implemented in the preoperative workup of endometrial cancer ... -
Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies
(Peer reviewed; Journal article, 2021)Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ... -
Assessment of the quality of life in parents of children with ADHD : validation of the Multicultural Quality of Life in Norwegian pediatric mental health settings
(Peer reviewed; Journal article, 2021)Background: The brief generic Multicultural Quality of Life Index (MQLI) is a culturally informed self-report 10-item questionnaire used to measure health-related quality of life (QoL). QoL is an important outcome measure ... -
Association between exposure to different stone aggregates from asphalt and blood coagulability: A human exposure chamber study
(Peer reviewed; Journal article, 2021)A large fraction of particulate matter (PM), especially PM10, concentrations are due to non-exhaust emissions, such as road abrasion and wear on tires and brake pads. Concentrating on road abrasion, we aimed to investigate ... -
Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study
(Peer reviewed; Journal article, 2021)Background: It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated ... -
Rhinosinusitis without Nasal Polyps in COPD
(Peer reviewed; Journal article, 2020)The validity of the united airway disease concept for rhinosinusitis (RS) and chronic obstructive pulmonary disease (COPD) has been questioned because of methodological limitations in previous studies. In this study we ...