Blar i St. Olavs hospital på tidsskrift "Journal of Cachexia, Sarcopenia and Muscle"

Viser treff 1-6 av 6

    • Associations between muscle measures, survival and toxicity in patients with limited disease small cell lung cancer receiving concurrent chemoradiotherapy 

      Halvorsen, Tarje Onsøien; Valan, Christine Damgaard; Jordhøy, Marit Slaaen; Grønberg, Bjørn Henning (Peer reviewed; Journal article, 2020)
      Background Standard treatment for patients with limited stage small cell lung cancer (LS SCLC) is concurrent platinum– etoposide chemotherapy and thoracic radiotherapy (TRT). Up to 30% of patients are cured, but severe ...

    • Associations between severe co-morbidity and muscle measures in advanced non-small cell lung cancer patients 

      Grønberg, Bjørn Henning; Valan, Christine Damgaard; Halvorsen, Tarje Onsøien; Sjøblom, Bjørg; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Introduction Several studies show that low skeletal muscle index (SMI) and low skeletal muscle density (SMD) are negative prognostic factors and associated with more toxicity from systemic therapy in cancer patients. ...

    • Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia 

      Pettersen, Kristine; Andersen, Sonja Benedikte; van der Veen, Anna; Nonstad, Unni; Hatakeyema, Shinji; Lambert, Christian; Lach-Trifilieff, Estelle; Moestue, Siver Andreas; Kim, Jana; Grønberg, Bjørn Henning; Schilb, Alain; Jacobi, Carsten; Bjørkøy, Geir (Journal article; Peer reviewed, 2019)
      Background The majority of patients with advanced cancer develop cachexia, a weight loss syndrome that severely reduces quality of life and limits survival. Our understanding of the underlying mechanisms that cause the ...

    • Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi-cohort analysis. 

      Martins, Lisa; Muscaritoli, Maurizio; Bourdel-Marchasson, I; Kubrac, C; Laird, Barry J.; Gagnon, B; Chasen, Martin; Gioulbasanis, Ioannis; Wallengren, Ola; Voss, A.C.; Goldwasser, F; Jagoe, T; Deans, Chris; Bozzetti, F; Strasser, Florian; Thoresen, Lene; Kazemi, S; Baracos, V. Elaine; Senesse, Pierre (Peer reviewed; Journal article, 2021)
      Background - Cancer-associated weight loss (WL) associates with increased mortality. International consensus suggests that WL is driven by a variable combination of reduced food intake and/or altered metabolism, the latter ...

    • Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients 

      Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)
      Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ...

    • Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series 

      McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)
      In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ...