Browsing St. Olavs hospital by Journals "Frontiers in Aging Neuroscience"
Now showing items 1-4 of 4
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5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did. A Generation 100 Substudy
(Peer reviewed; Journal article, 2021)Background: Aerobic exercise is proposed to attenuate cognitive decline in aging. We investigated the effect of different aerobic exercise interventions and cardiorespiratory fitness (CRF) upon cognition throughout a 5-year ... -
Bridging the gap between fluid biomarkers for Alzheimer’s disease, model systems, and patients
(Peer reviewed; Journal article, 2020)Alzheimer’s disease (AD) is a debilitating neurodegenerative disease characterized by the accumulation of two proteins in fibrillar form: amyloid-β (Aβ) and tau. Despite decades of intensive research, we cannot yet pinpoint ... -
Elevated levels of cerebrospinal fluid α-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers
(Journal article; Peer reviewed, 2014)Mutations in the leucine-rich repeat kinase 2 gene are the most common cause of autosomal dominant Parkinson’s disease (PD). To assess the cerebrospinal fluid (CSF) levels of α-synuclein oligomers in symptomatic and ... -
Predicting the Emergence of Major Neurocognitive Disorder Within Three Months After a Stroke
(Peer reviewed; Journal article, 2021)Background: Neurocognitive disorder (NCD) is common after stroke, with major NCD appearing in about 10% of survivors of a first-ever stroke. We aimed to classify clinical- and imaging factors related to rapid development ...