• A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders 

      Schou, Morten Brix; Sæther, Sverre Georg; Drange, Ole Kristian; Brenner, Eiliv; Crespi, Joan Vidal; Eikenes, Live; Mykland, Martin Syvertsen; Pintzka, Carl Wolfgang Schøyen; Håberg, Asta; Sand, Trond; Vaaler, Arne; Kondziella, Daniel (Peer reviewed; Journal article, 2019)
      The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ...
    • Association between polarity of first episode and solar insolation in bipolar I disorder 

      Bauer, Michael; Glenn, Tasha; Achtyes, Eric D.; Alda, Martin; Agaoglu, Esen; Altınbaş, Kürşat; Andreassen, Ole; Angelopoulos, Elias; Ardau, Raffaella; Aydin, Memduha; Ayhan, Yavuz; Baethge, Christopher; Bauer, Rita; Baune, Bernhard T.; Balaban, Ceylan; Becerra-Palars, Claudia; Behere, Aniruddh P.; Behere, Prakash B.; Belete, Habte; Belete, Tilahun; Belizario, Gabriel Okawa; Bellivier, Frank; Belmaker, Robert H.; Benedetti, Francesco; Berk, Michael; Bersudsky, Yuly; Bicakci, Şule; Birabwa-Oketcho, Harriet; Bjella, Thomas; Brady, Conan; Cabrera, Jorge; Cappucciati, Marco; Castro, Angela Marianne Paredes; Chen, Wei-Ling; Cheung, Eric Y.W.; Chiesa, Silvia; Crowe, Marie; Cuomo, Alessandro; Dallaspezia, Sara; Del Zompo, Maria; Desai, Pratikkumar; Dodd, Seetal; Etain, Bruno; Fagiolini, Andrea; Fellendorf, Frederike T.; Ferensztajn-Rochowiak, Ewa; Fiedorowicz, Jess G.; Fountoulakis, Kostas N.; Frye, Mark A.; Geoffroy, Pierre A.; Gonzalez-Pinto, Ana; Gottlieb, John F.; Grof, Paul; Haarman, Bartholomeus C.M.; Harima, Hirohiko; Hasse-Sousa, Mathias; Henry, Chantal; Høffding, Lone; Houenou, Josselin; Imbesi, Massimiliano; Isometsä, Erkki T.; Ivkovic, Maja; Janno, Sven; Johnsen, Simon; Kapczinski, Flávio; Karakatsoulis, Gregory N.; Kardell, Mathias; Kessing, Lars Vedel; Kim, Seong Jae; König, Barbara; Kot, Timur L.; Koval, Michael; Kunz, Mauricio; Lafer, Beny; Landén, Mikael; Larsen, Erik R.; Lenger, Melanie; Lewitzka, Ute; Licht, Rasmus W.; Lopez-Jaramillo, Carlos; MacKenzie, Alan; Madsen, Helle Østergaard; Madsen, Simone Alberte Kongstad A.; Mahadevan, Jayant; Mahardika, Agustine; Manchia, Mirko; Marsh, Wendy; Martinez-Cengotitabengoa, Monica; Martiny, Klaus; Mashima, Yuki; McLoughlin, Declan M.; Meesters, Ybe; Melle, Ingrid; Meza-Urzúa, Fátima; Mok, Yee Ming; Monteith, Scott; Moorthy, Muthukumaran; Morken, Gunnar; Mosca, Enrica; Mozzhegorov, Anton A.; Munoz, Rodrigo; Mythri, Starlin V.; Nacef, Fethi; Nadella, Ravi K.; Nakanotani, Takako; Nielsen, René Ernst; O'Donovan, Claire; Omrani, Adel; Osher, Yamima; Ouali, Uta; Pantovic-Stefanovic, Maja; Pariwatcharakul, Pornjira; Petite, Joanne; Pfennig, Andrea; Ruiz, Yolanda Pica; Pinna, Marco; Pompili, Maurizio; Porter, Richard; Quiroz, Danilo; Rabelo-da-Ponte, Francisco Diego; Ramesar, Raj; Rasgon, Natalie; Ratta-apha, Woraphat; Ratzenhofer, Michaela; Redahan, Maria; Reddy, M.S.; Reif, Andreas; Reininghaus, Eva Z.; Richards, Jenny Gringer; Ritter, Philipp; Rybakowski, Janusz K.; Sathyaputri, Leela; Scippa, Ângela M.; Simhandl, Christian; Smith, Daniel; Smith, José; Stackhouse, Paul W.; Stein, Dan J.; Stilwell, Kellen; Strejilevich, Sergio; Su, Kuan-Pin; Subramaniam, Mythily; Sulaiman, Ahmad Hatim; Suominen, Kirsi; Tanra, Andi J.; Tatebayashi, Yoshitaka; Teh, Wen Lin; Tondo, Leonardo; Torrent, Carla; Tuinstra, Daniel; Uchida, Takahito; Vaaler, Arne; Vieta, Eduard; Viswanath, Biju; Yoldi-Negrete, Maria; Yalcinkaya, Oguz Kaan; Young, Allan H.; Zgueb, Yosra; Whybrow, Peter C. (Peer reviewed; Journal article, 2022)
      Objective Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar insolation ...
    • Cytokines in agitated and non-agitated patients admitted to an acute psychiatric department: A cross-sectional study 

      Larsen, Jeanette Brun; Stunes, Astrid Kamilla; Vaaler, Arne; Reitan, Solveig Merete Klæbo (Journal article; Peer reviewed, 2019)
      Background:Different psychiatric diagnostic groups have been reported to have cytokine levels deviating from healthy controls. In acute clinical settings however, the specific challenging symptoms and signs are more important ...
    • Cytokines in Relation to Motor Activity in an Acute Psychiatric Population 

      Larsen, Jeanette Brun; Stunes, Astrid Kamilla; Iversen, Valentina Cabral; Vaaler, Arne; Reitan, Solveig Merete Klæbo (Peer reviewed; Journal article, 2019)
      Background: Deviations in motor activity are important clinical features of several psychiatric disorders in an acute state. Immune activity is associated with several psychiatric disorders and may affect motor activity. ...
    • Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study 

      Drange, Ole Kristian; Sæther, Sverre Georg; Finseth, Per Ivar; Morken, Gunnar; Vaaler, Arne; Arntsen, Vibeke; Henning, Oliver Johannes; Andreassen, Ole Andreas; Elvsåshagen, Torbjørn; Malt, Ulrik Fredrik; Bøen, Erlend (Peer reviewed; Journal article, 2020)
      Background A diagnosis of bipolar II disorder requires that the symptoms cannot be better explained by a medical condition. Epilepsy is in some cases associated with an affective syndrome mimicking an unstable bipolar ...
    • Epilepsy and other seizure disorders in acute psychiatric inpatients 

      Nakken, Erlend Iversen; Grinde, Frithjof; Vaaler, Arne; Drange, Ole Kristian; Brodtkorb, Eylert; Sæther, Sverre Georg (Peer reviewed; Journal article, 2021)
      Background: It is well known that patients with epilepsy have a high rate of psychiatric comorbidity. However, studies exploring epilepsy in psychiatric cohorts are scarce. The aim of this study was to examine the prevalence ...
    • Exploring associations between the Modular Assessment of Risk for Imminent Suicide (MARIS) questionnaire and recent suicidal ideation and behavior among patients admitted at an acute psychiatric inpatient department 

      Høyen, Karina Sagmo; Cohen, Lisa Janet; Solem, Stian; Prestmo, Astrid; Sørensen, Kjetil; Salvesen, Øyvind; Hjemdal, Odin; Vaaler, Arne; Torgersen, Terje (Peer reviewed; Journal article, 2023)
      Purpose The aim of the present study was to investigate the psychometric validity of the Modular Assessment of Risk for Imminent Suicide (MARIS) questionnaire in relation to recent suicidal ideation and behavior among a ...
    • Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study 

      Tunset, Mette Elise; Haslene-Hox, Hanne; Bossche, Tim Van Den; Vaaler, Arne; Sulheim, Einar; Kondziella, Daniel (Peer reviewed; Journal article, 2020)
      Extracellular vesicles (EVs) are cell-derived structures that transport proteins, lipids and nucleic acids between cells, thereby affecting the phenotype of the recipient cell. As the content of EVs reflects the status of ...
    • Identification of unhealthy alcohol use by self-report and phosphatidylethanol (PEth) blood concentrations in an acute psychiatric department 

      Finanger, Trine; Vaaler, Arne; Spigset, Olav; Aamo, Trond Oskar; Andreassen, Trine Naalsund; Gråwe, Rolf W.; Skråstad, Ragnhild Bergene (Peer reviewed; Journal article, 2022)
      Background The use of standard screening methods could improve the detection rate of unhealthy alcohol use in patients admitted to psychiatric acute and emergency departments. The aim of the present study was to investigate ...
    • Imminent and Short-Term Risk of Death by Suicide in 7,000 Acutely Admitted Psychiatric Inpatients 

      Fredriksen, Kristin Jørstad; Bartz-Johannessen, Christoffer; Schøyen, Helle Kristine; Vaaler, Arne; Walby, Fredrik A; Hegelstad, Wenche (Peer reviewed; Journal article, 2022)
      Objective: To prospectively investigate the predictive value of diagnosis, suicidal behavior, and subjectively experienced depressed mood for imminent risk of suicide death. Methods: This prospective study included a ...
    • Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness 

      Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø; Smelror, Runar Elle; Wedervang-Resell, Kirsten; Nerland, Stener; Westlye, Lars Tjelta; Nærland, Terje; Myhre, Anne Margrethe; Joa, Inge; Reitan, Solveig Merete Klæbo; Vaaler, Arne; Morken, Gunnar; Bøen, Erlend; Elvsåshagen, Torbjørn; Boye, Birgitte; Malt, Ulrik Fredrik; Aukrust, Pål; Skrede, Silje; Kroken, Rune Andreas; Johnsen, Erik; Djurovic, Srdjan; Andreassen, Ole; Ueland, Thor; Agartz, Ingrid (Peer reviewed; Journal article, 2021)
      Background Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ...
    • Mortality among patients discharged from an acute psychiatric department: A 5-year prospective study 

      Prestmo, Astrid; Høyen, Karina Sagmo; Vaaler, Arne; Torgersen, Terje; Drange, Ole Kristian (Peer reviewed; Journal article, 2020)
      The primary aim of the study was to explore the post discharge standardized mortality ratio of patients from an acute psychiatric department in Norway. The secondary aims were to explore if the standardized mortality ratio ...
    • Non-disclosure of suicidal ideation in psychiatric inpatients: Rates and correlates 

      Høyen, Karina Sagmo; Solem, Stian; Cohen, Lisa Janet; Prestmo, Astrid; Hjemdal, Odin; Vaaler, Arne; Galynker, Igor; Torgersen, Terje (Peer reviewed; Journal article, 2021)
      The study explored how common non-disclosure of suicidal ideation is in a sample of adult psychiatric inpatients (N = 171) plus associated patient characteristics. A large percentage (51.5%) withheld some information on ...
    • Quality of clinical management of cardiometabolic risk factors in patients with severe mental illness in a specialist mental health care setting 

      Ringen, Petter Andreas; Lund-Stenvold, Elisabeth Haug; Andreassen, Ole; Gaarden, Torfinn Lødøen; Hartberg, Cecilie Bhandari; Johnsen, Erik; Myklatun, Silje; Osnes, Kåre; Sørensen, Kirsten; Sørensen, Kjetil; Vaaler, Arne; Tonstad, Serena; Engh, John; Høye, Anne (Peer reviewed; Journal article, 2022)
      Purpose: Cardiometabolic disease in patients with severe mental illness is a major cause of shortened life expectancy. There is sparse evidence of real-world clinical risk prevention practice. We investigated levels of ...
    • Research based on existing clinical data and biospecimens: a systematic study of patients’ opinions 

      Eikemo, Hilde; Roten, Linda Tømmerdal; Vaaler, Arne (Peer reviewed; Journal article, 2022)
      Background The aim of the present survey was to investigate newly discharged hospital patients’ opinions on secondary use of their hospital data and biospecimens within the context of health research in general and, ...
    • Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders 

      Blokland, Gabriella A. M.; Grove, Jakob; Chen, Chia-Yen; Cotsapas, Chris; Tobet, Stuart; Handa, Robert; St Clair, David; Lencz, Todd; Mowry, Bryan J.; Periyasamy, Sathish; Tooney, Paul A.; Kelly, Brian; Kirov, George; Sullivan, Patrick F.; Corvin, Aiden; Riley, Brien P.; Esko, Tonu; Milani, Lili; Palotie, Aarno; Ehrenreich, Hannelore; Sham, Pak C.; Iwata, Nakao; Weinberger, Daniel R.; Gejman, Pablo V.; Sanders, Alan R.; Buxbaum, Joseph D.; Rujescu, Dan; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Bramon, Elvira; Murray, Robin M.; Pato, Michele T.; Lee, Jimmy; Melle, Ingrid; Molden, Espen; Ophoff, Roel A.; McQuillin, Andrew; Adolfsson, Rolf; Martin, Nicholas G.; Fullerton, Janice M.; Mitchell, Philip B.; Schofield, Peter R.; Forstner, Andreas J.; Degenhardt, Franziska; Comes, Ashley L.; Smeland, Olav Bjerkehagen; Vaaler, Arne; Andreassen, Ole; Jönsson, Erik Gunnar (Peer reviewed; Journal article, 2021)
      Background Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for shared genetic risk and sex differences ...
    • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 

      Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)
      Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...