• Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema 

      Bordoni, Luca; Thorén, Anna Elisabeth; Gutiérrez-Jiménez, Eugenio; Åbjørsbråten, Knut Sindre; Bjørnstad, Daniel Marelius; Tang, Wannan; Stern, Mette; Østergaard, Leif; Nagelhus, Erlend Arnulf; Frische, Sebastian; Ottersen, Ole Petter; Enger, Rune (Peer reviewed; Journal article, 2023)
      Brain edema is a feared complication to disorders and insults affecting the brain. It can be fatal if the increase in intracranial pressure is sufficiently large to cause brain herniation. Moreover, accruing evidence ...
    • Increased membrane Ca<sup>2+</sup> permeability drives astrocytic Ca<sup>2+</sup> dynamics during neuronal stimulation at excitatory synapses 

      Hjukse, Jarand Berg; Fernández de la Puebla, Mario; Vindedal, Gry Fluge; Sprengel, Rolf; Jensen, Vidar; Nagelhus, Erlend Arnulf; Tang, Wannan (Peer reviewed; Journal article, 2023)
      Astrocytes are intricately involved in the activity of neural circuits; however, their basic physiology of interacting with nearby neurons is not well established. Using two-photon imaging of neurons and astrocytes during ...