Blar i St. Olavs hospital på forfatter "Eldholm, Rannveig Sakshaug"

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    • Applicability of the locus of control of behaviour scale for people with dementia 

      Halse, Ingeborg; Björklöf, Guro Hanevold; Engedal, Knut; Rokstad, Anne Marie Mork; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Selbæk, Geir; Barca, Maria Lage (Journal article; Peer reviewed, 2019)
      Objective: To investigate the applicability of the Locus of Control of Behaviour scale (LoCB) for people with dementia. Method: A sample of 534 participants with dementia (78.4 mean age, 58% female) were included. Assessment ...

    • The association between clinically evaluated cognitive function and oral health in Norwegian older adults: The HUNT Study 

      Dénos, Marion Nicole Marie; Asante, Ernest Obeng; Eldholm, Rannveig Sakshaug; Selbæk, Geir; Skjellegrind, Håvard Kjesbu; Mai, Xiao-Mei; Yue, Chen; Sun, Yi-Qian (Journal article; Peer reviewed, 2024)
      Poor oral health and neurocognitive disorders (NCDs) are both important public health challenges in the general older population.1, 2 Older adults with NCDs may have poorer oral health due to decline in self-care, medication ...

    • Cerebrospinal fluid catecholamines in Alzheimer's disease patients with and without biological disease 

      Henjum, Kristi; Watne, Leiv; Godang, Kristin; Halaas, Nathalie Bodd; Eldholm, Rannveig Sakshaug; Blennow, Kaj; Zetterberg, Henrik; Saltvedt, Ingvild; Bollerslev, Jens; Knapskog, Anne Brita (Journal article; Peer reviewed, 2022)
      Noradrenergic and dopaminergic neurons are involved in cognitive functions, relate to behavioral and psychological symptoms in dementia and are affected in Alzheimer’s disease (AD). Amyloid plaques (A), neurofibrillary ...

    • Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

      Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)
      Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...

    • Change in physical activity and systolic blood pressure trajectories throughout mid-life and the development of dementia in older age: the HUNT study 

      Lerfald, Maren; Lydersen, Stian; Zotcheva, Ekaterina; Nilsen, Tom Ivar Lund; Eldholm, Rannveig Sakshaug; Martinez-Velilla, Nicolás; Selbæk, Geir; Ernstsen, Linda (Peer reviewed; Journal article, 2023)
      Background There is lack of research on combinations of possible modifiable risk factors for dementia in a life-time perspective. Dementia has currently no cure, and therefore new knowledge of preventive factors is ...

    • Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium 

      Aksnes, Mari; Schibstad, Mari Haavig; Chaudhry, Farrukh Abbas; Neerland, Bjørn Erik; Caplan, Gideon A.; Saltvedt, Ingvild Tina; Eldholm, Rannveig Sakshaug; Myrstad, Marius; Edwin, Trine Holt; Persson, Karin Ester Torun; Idland, Ane-Victoria; Pollmann, Christian Thomas; Bjørkholt Olsen, Roy; Wyller, Torgeir Bruun; Zetterberg, Henrik; Cunningham, Emma; Watne, Leiv (Journal article; Peer reviewed, 2024)
      Background The aetiology of delirium is not known, but pre-existing cognitive impairment is a predisposing factor. Here we explore the associations between delirium and cerebrospinal fluid (CSF) levels of matrix ...

    • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

      Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)
      Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...

    • Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease 

      Knapskog, Anne Brita; Aksnes, Mari; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Saltvedt, Ingvild Tina; Solvang, Stein-Erik Hafstad; Watne, Leiv (Peer reviewed; Journal article, 2023)
      INTRODUCTION The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a ...

    • The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study 

      Aam, Stina; Gynnild, Mari Nordbø; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Lydersen, Stian; Knapskog, Anne Brita; Ihle-Hansen, Hege; Ellekjær, Hanne; Eldholm, Rannveig Sakshaug; Fure, Brynjar (Peer reviewed; Journal article, 2021)
      Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ...

    • A Machine Learning Approach to Predict Post-stroke Fatigue. The Nor-COAST study 

      Luzum, Geske; Thrane, Gyrd; Aam, Stina; Eldholm, Rannveig Sakshaug; Grambaite, Ramune; Munthe-Kaas, Ragnhild; Thingstad, Anne Pernille Mæhle; Saltvedt, Ingvild; Askim, Torunn (Journal article; Peer reviewed, 2014)
      Objective: This study aimed to predict fatigue 18 months post-stroke by utilizing comprehensive data from the acute and sub-acute phases after stroke in a machine-learning set-up. Design: A prospective multicenter ...

    • Prevalence and change in alcohol consumption in older adults over time, assessed with self-report and Phosphatidylethanol 16:0/18:1 —The HUNT Study 

      Tevik, Kjerstin Elisabeth; Skråstad, Ragnhild Bergene; Saltyte Benth, Jurate; Selbæk, Geir; Bergh, Sverre; Eldholm, Rannveig Sakshaug; Krokstad, Steinar; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2024)
      Background Changes in alcohol consumption may affect older adults’ health. We examined prevalence and changes in the alcohol consumption of older women and men (≥65 years) in Norway over a 24-year period. Methods Data ...

    • Sex-specific associations of kynurenic acid with neopterin in Alzheimer’s disease 

      Knapskog, Anne-Brita; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Solvang, Stein-Erik Hafstad; Saltvedt, Ingvild Tina; Watne, Leiv; Aksnes, Mari (Journal article; Peer reviewed, 2024)
      Background: Sex differences in neuroinflammation could contribute to women’s increased risk of Alzheimer’s disease (AD), providing rationale for exploring sex-specific AD biomarkers. In AD, dysregulation of the kynurenine ...

    • Sex-specific associations of matrix metalloproteinases in Alzheimer’s disease 

      Aksnes, Mari; Edwin, Trine Holt; Saltvedt, Ingvild Tina; Eldholm, Rannveig Sakshaug; Chaudhry, Farrukh Abbas; Halaas, Nathalie Bodd; Myrstad, Marius; Watne, Leiv; Knapskog, Anne Brita (Peer reviewed; Journal article, 2023)
      Introduction Alzheimer’s disease (AD) can be characterised in vivo by biomarkers reflecting amyloid-β (Aβ) and tau pathology. However, there is a need for biomarkers reflecting additional pathological pathways. Matrix ...

    • Vitamin D Status Over Time and Cognitive Function in Norwegian Older Adults: A Prospective Cohort of the HUNT Study 

      Asante, Ernest Obeng; Mai, Xiao-Mei; Eldholm, Rannveig Sakshaug; Skjellegrind, Håvard; Kolberg, Marit; Brumpton, Ben Michael; Selbæk, Geir; Chen, Y.; Sun, Yi-Qian (Peer reviewed; Journal article, 2022)
      Background There is conflicting evidence regarding the association between vitamin D status and cognitive function in population studies. The use of one-time vitamin D measurement in cognitive health studies may not ...