Browsing St. Olavs hospital by Title

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    • Top Ten Tips Palliative Care Clinicians Should Know About Cachexia 

      Blum, David; Vagnildhaug, Ola Magne; Stene, Guro Birgitte; Maddocks, Matthew; Sørensen, Jonas; Laird, Barry J; Prado, Carla M.; Solheim, Tora S; Arends, Jann; Hopkinson, Jane; Jones, Christopher A.; Schlögl, Mathias (Peer reviewed; Journal article, 2023)
      Cachexia is a multifactorial syndrome that is common in cancer and chronic disease. It is often underdiagnosed and therefore goes untreated or undertreated. Cachexia causes suffering across biopsychosocial domains and ...

    • Total late effect burden in long-term lymphoma survivors after high-dose therapy with autologous stem-cell transplant and its effect on health-related quality of life 

      Smeland, Knut Bjøro; Holte, Harald; Fagerli, Unn-Merete; Bersvendsen, Hanne Skjerven; Hjermstad, Marianne Jensen; Loge, Jon Håvard; Murbræch, Klaus; Linnsund, Marianne Dahl; Fluge, Øystein; Stenehjem, Jo Steinson; Samersaw-Lund, May Brit; Kvaløy, Stein Olav; Kiserud, Cecilie E. (Peer reviewed; Journal article, 2022)
      Lymphoma survivors after high-dose therapy with autologous stem-cell transplant (HDT-ASCT) are at risk of several late effects, which might impair their health-related quality of life (HRQoL). We assessed the total late ...

    • Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group 

      Olsen, Alexander; Babikian, Talin; Bigler, Erin D.; Caeyenberghs, Karen; Conde, Virginia; Dams-O’Connor, Kristen; Dobryakova, Ekaterina; Genova, Helen; Grafman, Jordan; Håberg, Asta; Heggland, Ingrid; Hellstrøm, Torgeir; Hodges, Cooper B.; Irimia, Andrei; Jha, Ruchira M.; Johnson, Paula K.; Koliatsos, Vassilis E.; Levin, Harvey; Li, Lucia M.; Lindsey, Hannah M.; Livny, Abigail; Løvstad, Marianne; Medaglia, John; Menon, David; Mondello, Stefania; Monti, Martin M.; Newcombe, Virginia F.J.; Petroni, Agustin; Ponsford, Jennie; Sharp, David; Spitz, Gershon; Westlye, Lars Tjelta; Thompson, Paul M.; Dennis, Emily L.; Tate, David; Wilde, Elisabeth A.; Hillary, Frank G. (Peer reviewed; Journal article, 2020)
      The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major ...

    • Towards human-level performance on automatic pose estimation of infant spontaneous movements 

      Groos, Daniel; Adde, Lars; Støen, Ragnhild; Ramampiaro, Heri; Ihlen, Espen Alexander F. (Peer reviewed; Journal article, 2021)
      Assessment of spontaneous movements can predict the long-term developmental disorders in high-risk infants. In order to develop algorithms for automated prediction of later disorders, highly precise localization of segments ...

    • Trace elements in whole blood in the general population in Trøndelag County, Norway: The HUNT3 Survey 

      Simic, Anica; Hansen, Ailin Falkmo; Syversen, Tore; Lierhagen, Syverin; Ciesielski, Tomasz Maciej; Romundstad, Pål Richard; Midthjell, Kristian; Åsvold, Bjørn Olav; Flaten, Trond Peder (Journal article; Peer reviewed, 2021)
      Background: Biomonitoring of a cohort within a large health survey can provide reliable information on trace element status. The main aims of this study were 1) to determine the concentrations of 28 trace elements in whole ...

    • Tracheal cancer: a rare and deadly but potentially curable disease that also affects younger people 

      Nilssen, Yngvar; Solberg, Steinar; Brustugun, Odd Terje; Møller, Bjørn; Sundset, Arve; Wahl, Sissel Gyrid Freim; Helland, Åslaug (Peer reviewed; Journal article, 2023)
      OBJECTIVES The incidence of tracheal cancer is low, few clinicians get much experience and the awareness may be low. Recent data on the treatment and outcome are limited. The aim of the present study was to present ...

    • Tracheal intubation in traumatic brain injury: a multicentre prospective observational study 

      Gravesteijn, BY; Sewalt, Charlie; Nieboer, D.; Menon, David K.; Maas, Andrew I. R.; Lecky, Fiona E.; Klimek, Markus; Lingsma, Hester F; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background: We aimed to study the associations between pre- and in-hospital tracheal intubation and outcomes in traumatic brain injury (TBI), and whether the association varied according to injury severity. Methods: Data ...

    • Tracheostomy practice and timing in traumatic brain-injured patients: a CENTER-TBI study 

      Robba, Chiara; Galimberti, Stefania; Graziano, Francesca; Wiegers, E; Lingsma, Hester F; Iaquaniello, Carolina; Stocchetti, Nino; Menon, David; Citerio, Giuseppe; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Sandrød, Oddrun; Schirmer-Mikalsen, Kari; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Beer, Ronny; Bellander, Bo-Michael; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Biqiri, Erta; Blaabjerg, Morten; Brorsson, Camilla; Buki, Andras; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Castaño-León, Ana M.; Chevallard, Giorgio; Chieregato, Arturo; Coburn, Mark; Coles, Jonathan; Cooper, Jamie; Correia, Marta; Czeiter, Endre (Peer reviewed; Journal article, 2020)
      Purpose Indications and optimal timing for tracheostomy in traumatic brain-injured (TBI) patients are uncertain. This study aims to describe the patients’ characteristics, timing, and factors related to the decision to ...

    • Tracking impact of interstitial lung disease in systemic sclerosis in a complete nationwide cohort 

      Hoffmann-Vold, Anna-Maria; Fretheim, Håvard Halland; Halse, Anne-Kristine; Seip, Marit; Bitter, Helle; Wallenius, Marianne; Garen, Torhild Oddveig; Salberg, Anne; Brunborg, Cathrine; Midtvedt, Øyvind; Lund, May-Brith; Aaløkken, Trond M; Molberg, Øyvind (Journal article; Peer reviewed, 2019)
      Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc), but there are no precise, population-based data on its overall impact, limiting opportunities for screening and management ...

    • Tracking-based mitral annular plane systolic excursion (MAPSE) measurement using deep learning in B-mode ultrasound 

      Smistad, Erik; Østvik, Andreas; Grue, Jahn Frederik; Dalen, Håvard; Løvstakken, Lasse (Peer reviewed; Journal article, 2022)
      Mitral annular plane systolic excursion (MAPSE) is an important measure of left ventricular function. Current clinical practice is to measure it manually using M-mode ultrasound imaging which has several disadvantages such ...

    • Trajectories of Pain in Patients Undergoing Lung Cancer Surgery: A Longitudinal Prospective Study. 

      Gjeilo, Kari Hanne; Oksholm, Trine; Follestad, Turid; Wahba, Alexander; Rustøen, Tone (Peer reviewed; Journal article, 2019)
      Context Lung cancer surgery is among the surgical procedures associated with the highest prevalence of pain, but prospective longitudinal studies after the pain trajectory are scarce. Objectives We aimed to describe the ...

    • Trajectories of Persistent Postconcussion Symptoms and Factors Associated With Symptom Reporting After Mild Traumatic Brain Injury 

      Fordal, Linda; Stenberg, Jonas; Iverson, Grant L.; Saksvik, Simen Berg; Karaliute, Migle; Vik, Anne; Olsen, Alexander; Skandsen, Toril (Peer reviewed; Journal article, 2021)
      Objective To examine the trajectories of persistent postconcussion symptoms (PPCS) after mild traumatic brain injury (MTBI) and to investigate which injury-related and personal factors are associated with symptom reporting. ...

    • Trajectory of health-related quality of life during the last year of life in patients with advanced non-small–cell lung cancer 

      Kristensen, Are Korsnes; Grønberg, Bjørn Henning; Fløtten, Øystein; Kaasa, Stein; Solheim, Tora S (Peer reviewed; Journal article, 2022)
      Background The aims of this study were to assess the trajectory of health-related quality of life (HRQOL) during the last year of life in patients with advanced non-small–cell lung cancer (NSCLC) and to explore when and ...

    • Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease 

      Zheng, Jie; Zhang, Yuemiao; Rasheed, Humaira; Walker, Venexia M.; Sugawara, Yuka; Li, Jiachen; Leng, Yue; Elsworth, Benjamin; Wootton, Robyn E.; Fang, Si; Yang, Qian; Burgess, Stephen; Haycock, Philip C.; Borges, Maria Carolina; Carnegie, Rebecca; Cho, Yoonsu; Howell, Amy; Robinson, Jamie; Thomas, Laurent; Brumpton, Ben Michael; Hveem, Kristian; Hallan, Stein; Franceschini, Nora; Morris, Andrew P.; Köttgen, Anna; Pattaro, Cristian; Wuttke, Matthias; Yamamoto, Masayuki; Kashihara, Naoki; Akiyama, Masato; Kanai, Masahiro; Matsuda, Koichi; Kamatani, Yoichiro; Okada, Yukinori; Walters, Robin; Millwood, Iona Y.; Chen, Zhengming; Smith, George Davey; Barbour, Sean; Yu, Canqing; Åsvold, Bjørn Olav; Zhang, Hong; Gaunt, Tom R. (Peer reviewed; Journal article, 2021)
      Background: This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization. ...

    • Trans-fatty acids and survival in renal transplantation 

      Chandra, Anupam; Svensson, My Hanna Sofia; Åsberg, Anders; Schmidt, Erik Berg; Bjerve, Kristian S; Jenssen, Trond Geir; Hartmann, Anders; Ueland, Thor; Eide, Ivar Anders (Journal article; Peer reviewed, 2018)
      Objective High consumption of trans-fatty acids (TFAs) is associated with increased mortality. Design and methods Observational cohort study of 1.988 Norwegian renal transplant recipients with a median follow-up time ...

    • Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas 

      Cobo, Isidoro; Martinelli, Paola; Flández, Marta; Bakiri, Latifa; Zhang, Mingfeng; Carrillo-de-Santa-Pau, Enrique; Jia, Jinping; Lobo, Víctor J. Sánchez-Arévalo; Megías, Diego; Felipe, Irene; del Pozo, Natalia; Millán, Irene; Thommesen, Liv; Bruland, Torunn; Olson, Sara H.; Smith, Jill; Schoonjans, Kristina; Bamlet, William R.; Petersen, Gloria M.; Malats, Núria; Amundadóttir, Laufey T.; Wagner, Erwin F.; Real, Francisco X. (Journal article; Peer reviewed, 2018)
      Chronic inflammation increases the risk of developing one of several types of cancer. Inflammatory responses are currently thought to be controlled by mechanisms that rely on transcriptional networks that are distinct from ...

    • Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease 

      Escudero-hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Munch, Andreas (Peer reviewed; Journal article, 2021)
      Background and aims: The pathophysiology of the inflammatory bowel disease collagenous colitis (CC) is poorly described. Our aim was to use RNA sequencing of mucosal samples from patients with active CC, CC in remission, ...

    • Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project 

      Nordeng, Hedvig Marie Egeland; Wegler, Christine; Lindqvist, Annika; Melander, Erik; Magnusson, Mikaela; Gandia, Peggy; Panchaud, Alice; Baranczewski, Pawel; Spigset, Olav (Peer reviewed; Journal article, 2023)
      Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women at least ...

    • Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding 

      Amundsen, Siri; Nordeng, Hedvig; Nordeng, Hedvig Marie Egeland; Fuskevåg, Ole Martin; Nordmo, Elisabet; Nordmo, Elisabet N; Sager, Georg; Spigset, Olav (Peer reviewed; Journal article, 2021)
      Clinical data on the transfer of triptans into human breast milk remain scarce. In a lactation study including 19 breastfeeding women with migraine, we examined the excretion of six different triptans into milk. Following ...

    • Transfusion of red blood cells in coronary surgery: is there an effect on long-term mortality when adjusting for risk factors and postoperative complications? 

      Tran, Long; Greiff, Guri; Pleym, Hilde; Wahba, Alexander; Stenseth, Roar; Videm, Vibeke (Peer reviewed; Journal article, 2017)
      OBJECTIVES The aim of this study was to compare long-term mortality in patients undergoing primary isolated coronary artery bypass grafting who received ≥1 units of red blood cells (RBCs) or no RBCs. We hypothesized that ...