Blar i St. Olavs hospital på tittel

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    • Ultrasound-Mediated Delivery of Chemotherapy into the Transgenic Adenocarcinoma of the Mouse Prostate Model 

      Fagerland, Stein-Martin Tilrum; Berg, Sigrid; Hill, Deborah Katherine; Snipstad, Sofie; Sulheim, Einar; Hyldbakk, Astrid; Kim, Jana; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      Ultrasound (US) in combination with microbubbles (MB) has had promising results in improving delivery of chemotherapeutic agents. However, most studies are done in immunodeficient mice with xenografted tumors. We used two ...

    • An Unbalanced Chromosome Translocation Between 7p22 and 12q13 Leads to ACTB-GLI1 Fusion in Pericytoma 

      Panagopoulos, Ioannis; Gorunova, Ludmila; Rise, Tor Vikan; Andersen, Kristin; Micci, Francesca; Heim, Sverre (Peer reviewed; Journal article, 2020)
      Background/Aim: Since the first description of five pericytomas with the t(7;12)/ACTB-GLI1 fusion gene, only three new tumors were studied by both cytogenetics and molecular techniques. We report here genetic data on another ...

    • Uncertainty quantification and sensitivity analysis for computational FFR estimation in stable coronary artery disease 

      Fossan, Fredrik Eikeland; Sturdy, Jacob; Muller, Lucas Omar; Strand, Andreas; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Journal article; Peer reviewed, 2018)
      Purpose The main objectives of this study are to validate a reduced-order model for the estimation of the fractional flow reserve (FFR) index based on blood flow simulations that incorporate clinical imaging and ...

    • Understanding peer support: a qualitative interview study of doctors one year after seeking support 

      Horne, Ingrid Marie Taxt; Veggeland, Frode; Bååthe, Fredrik; Drewes, Christina; Rø, Karin (Peer reviewed; Journal article, 2023)
      Background Doctors’ health is of importance for the quality and development of health care and to doctors themselves. As doctors are hesitant to seek medical treatment, peer support services, with an alleged lower threshold ...

    • Understanding the possibilities and limitations of assistive technology in health and welfare services for people with intellectual disabilities, staff perspectives 

      Rasouli, Omid; Kvam, Lisbeth; Husby, Vigdis Schnell; Røstad, Monica; Witsø, Aud Elisabeth (Journal article; Peer reviewed, 2021)
      Purpose: Little is known regarding what assistive technology (AT) exists and how it is used in welfare services for people with intellectual disabilities (ID). This study aimed to explore healthcare staff’s perspectives ...

    • Understanding the relationship between cognitive performance and function in daily life after traumatic brain injury 

      Wilson, Lindsay; Horton, Lindsay; Kunzmann, Kevin; Sahakian, Barbara J.; Newcombe, Virginia; Stamatakis, E; Steinbuechel, Nicole; Cunitz, Kathrin; Covic, Amra; Maas, Andrew; van Praag, Dominigue; Menon, David; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo (Peer reviewed; Journal article, 2020)
      Objective: Cognitive impairment is a key cause of disability after traumatic brain injury (TBI) but relationships with overall functioning in daily life are often modest. The aim is to examine cognition at different levels ...

    • Undertriage in Trauma: An Ignored Quality Indicator? 

      Jeppesen, Elisabeth; Cuevas-Østrem, Mathias; Gram-Knutsen, Cathrine; Uleberg, Oddvar (Peer reviewed; Journal article, 2020)
      Background Early identification of life-threatening injuries is essential to reduce morbidity and mortality in trauma patients. Failure to detect severe injury may cause delayed diagnosis and therapeutic interventions ...

    • Undiagnosed diabetes: Prevalence and cardiovascular risk profile in a population-based study of 52,856 individuals. The HUNT Study, Norway 

      Bjarkø, Vera Vik; Haug, Eirin Beate; Sørgjerd, Elin Pettersen; Stene, Lars Christian Mørch; Lopez-Doriga Ruiz, Paz; Birkeland, Kåre Inge; Berg, Tore Julsrud; Gulseth, Hanne Løvdal; Iversen, Marjolein M.; Langhammer, Arnulf; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2022)
      Aims We investigated the current extent of undiagnosed diabetes and prediabetes and their associated cardiovascular risk profile in a population-based study. Methods All residents aged ≥20 years in the Nord-Trøndelag ...

    • Unidimensionality of the Strengths and Vulnerabilities Scales in the Short-Term Assessment of Risk and Treatability (START) 

      Whittington, Richard; Pollak, Charlotte; Keski-Valkama, Alice; Brown, Andrew; Haines, Alina; Bak, Jesper; Hvidhjelm, Jacob; Almvik, Roger; Palmstierna, Tom (Peer reviewed; Journal article, 2021)
      The Short-Term Assessment of Risk and Treatability (START) is a 20-item structured professional judgment instrument for assessing dynamic risk in mental health services. Much of the START research literature examines the ...

    • A universal outcome measure for headache treatments, care-delivery systems and economic analysis 

      Steiner, Timothy J; Linde, Mattias; Schnell-Inderst, Petra (Peer reviewed; Journal article, 2021)
      Background The first manuscript in this series delineated a model of structured headache services, potentially cost-effective but requiring formal cost-effectiveness analysis (CEA). We envisaged a need for a new outcome ...

    • Unsatisfactory risk factor control and high rate of new cardiovascular events in patients with myocardial infarction and prior coronary artery disease 

      Jortveit, Jarle; Halvorsen, Sigrun; Kaldal, Anete; Pripp, Are Hugo; Govatsmark, Ragna Elise Støre; Langørgen, Jørund (Peer reviewed; Journal article, 2019)
      Background: Patients with established coronary artery disease (CAD) have an increased risk of new cardiovascular events. An underuse of secondary preventive drugs has been observed, and many patients may not attain the ...

    • Update on genetic predisposition to colorectal cancer and polyposis 

      Valle, Laura; de Voer, Richarda M.; Goldberg, Yael; Sjursen, Wenche; Försti, Asta; Ruiz-Ponte, Clara; Caldés, Trinidad; Garré, Pilar; Olsen, Maren Fridtjofsen; Nordling, Margareta; Castellví-Bel, Sergi; Hemminki, Kari (Journal article; Peer reviewed, 2019)
      The present article summarizes recent developments in the characterization of genetic predisposition to colorectal cancer (CRC). The main themes covered include new hereditary CRC and polyposis syndromes, non-CRC hereditary ...

    • An Update on Prevalence, Assessment, and Risk Factors for Sleep Disturbances in Patients with Advanced Cancer—Implications for Health Care Providers and Clinical Research 

      Jakobsen, Gunnhild; Gjeilo, Kari Hanne; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Simple Summary This review focuses on sleep in patients with advanced cancer. Cancer patients experience multiple symptoms and they receive concomitant medications. These are all factors that may affect sleep. In this ...

    • Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil 

      Sarno, Antonio; Lundbæk, Marie Benner; Liabakk, Nina-Beate; Aas, Per Arne; Mjelle, Robin; Hagen, Lars; Sousa, Mirta; Krokan, Hans Einar; Kavli, Bodil Merete (Journal article; Peer reviewed, 2019)
      UNG is the major uracil-DNA glycosylase in mammalian cells and is involved in both error-free base excision repair of genomic uracil and mutagenic uracil-processing at the antibody genes. However, the regulation of UNG in ...

    • Urban–Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study 

      Solbakken, Siri Marie; Magnus, Jeanette H.; Meyer, Haakon E; Dahl, Cecilie; Stigum, Hein; Søgaard, Anne-Johanne; Holvik, Kristin; Tell, Grethe S.; Emaus, Nina; Forsmo, Siri; Gjesdal, Clara Gram; Schei, Berit; Vestergaard, Peter; Omsland, Tone Kristin (Journal article; Peer reviewed, 2019)
      Higher hip fracture incidence in urban than in rural areas has been demonstrated, but urban–rural differences in posthip fracture mortality have been less investigated, and the results are disparate. Hence, the aims of the ...

    • Ureteric injuries during hysterectomy—A Norwegian retrospective study of occurrence and claims for compensation over an 11-year period 

      Ravlo, Merethe; Moen, Mette Haase; Bukholm, Ida Rashida Khan; Lieng, Marit; Vanky, Eszter (Peer reviewed; Journal article, 2021)
      Introduction: Ureteric injury is a rare but serious, iatrogenic complication of hysterectomy. The risk depends on indication for surgery, predisposing risk factors, and peroperative conditions. Our aims were to evaluate ...

    • Usability of the IDDEAS prototype in child and adolescent mental health services: A qualitative study for clinical decision support system development 

      Clausen, Carolyn Elizabeth; Leventhal, Bennett; Nytrø, Øystein; Koposov, Roman A; Røst, Thomas Brox; Westbye, Odd Sverre; Koochakpour, Kaban; Frodl, Thomas; Stien, Ulrika Line; Skokauskas, Norbert (Peer reviewed; Journal article, 2023)
      Introduction: Child and adolescent mental health services (CAMHS) clinical decision support system (CDSS) provides clinicians with real-time support as they assess and treat patients. CDSS can integrate diverse clinical ...

    • Usage of Antivirals and the Occurrence of Antiviral Resistance in Norway 2022. RAVN 

      Kran, Anne-Marte Bakken; Håvelsrud, Othilde Elise; Storm, Margrethe Larsdatter; Blix, Hege Salvesen; Bragstad, Karoline; Stene-Johansen, Kathrine; Rohringer, Andreas; Tylden, Garth Daryl; Birkeland Kro, Grete; Rykkvin, Rikard; Ormaasen, Vidar; Marvik, Åshild; Njølstad, Gro; Nilsen, Hans-Johnny Schjelderup; Reikvam, Dag Henrik (Research report, 2023)

    • Use and impact of high intensity treatments in patients with traumatic brain injury across Europe: a CENTER-TBI analysis 

      Huijben, Jilske A.; Dixit, Abhishek; Stocchetti, Nino; Maas, Andrew I. R.; Lingsma, Hester F.; van der Jagt, Mathieu; Nelson, David; Citerio, Giuseppe; Wilson, Lindsay; Menon, David K.; Ercole, Ari; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria rosa; Cameron, Peter; Lozano, Guillermo carbayo; Carbonara, Marco; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Cnossen, Maryse; Coburn, Mark (Peer reviewed; Journal article, 2021)
      Purpose To study variation in, and clinical impact of high Therapy Intensity Level (TIL) treatments for elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI) across European Intensive Care ...

    • Use and validity of child neurodevelopment outcome measures in studies on prenatal exposure to psychotropic and analgesic medications – A systematic review 

      Andersen, Sarah Hjorth; Bromley, Rebecca; Ystrøm, Eivind; Lupattelli, Angela; Spigset, Olav; Nordeng, Hedvig Marie Egeland (Journal article; Peer reviewed, 2019)
      In recent years there has been increased attention to child neurodevelopment in studies on medication safety in pregnancy. Neurodevelopment is a multifactorial outcome that can be assessed by various assessors, using ...