St. Olavs hospital: Nye registreringer

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    • Primary Retroperitoneal Lymph Node Dissection as Treatment for Low-volume Metastatic Seminoma in a Population-based Cohort: The Swedish Norwegian Testicular Cancer Group Experience 

      Thor, Anna; Negaard, Helene Francisca Stigter; Grenabo Bergdahl, Anna; Almås, Bjarte; Larsen, Signe Melsen; Lundgren, Per-Olof; Gerdtsson, Axel; Halvorsen, Dag; Johannsdottir, Berglind; Jansson, Anna K.; Hellström, Martin; Wahlqvist, Rolf; Langberg, Carl W.; Hedlund, Annika; Akre, Olof; Glimelius, Ingrid; Ståhl, Olof; Haugnes, Hege Sagstuen; Cohn-Cedermark, Gabriella; Kjellman, Anders; Tandstad, Torgrim (Journal article; Peer reviewed, 2024)
      Background and objective There is an unmet need to avoid long-term morbidity associated with standard cytotoxic treatment for low-volume metastatic seminoma. Our aim was to assess the oncological efficacy and surgical ...

    • Parenteral Nutrition in Palliative Cancer Care: Detrimental, Futile, or Beneficial? 

      Løhre, Erik Torbjørn; Solheim, Tora S; Jakobsen, Gunnhild; Vagnildhaug, Ola Magne; Karlsen, Terese Louise Schmidberger; Habberstad, Ragnhild Hansdatter; Balstad, Trude Rakel; Thronæs, Morten (Journal article; Peer reviewed, 2024)
      Palliative cancer care patients may live for a long time, but malnutrition worsens the prognosis. Parenteral nutrition (PN) is suitable for replenishing a calorie deficit, but its advantages and tolerance late in the cancer ...

    • Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer—a prospective national multicentre study (EMIT-1) 

      Ohnstad, Hege Oma; Blix, Egil Støre; Akslen, Lars Andreas; Gilje, Bjørnar; Raj, Sunil Xavier; Skjerven, Helle; Borgen, Elin; Janssen, Emiel; Mortensen, Elin Synnøve; Brekke, Marianne B.; Falk, Ragnhild Sørum; Schlichting, Ellen; Boge, Beate; Songe-Møller, Silje; Olsson, Pernilla Marie A.; Heie, Anette; Mannsåker, Bård; Vestlid, Magdalena Aas; Kursetgjerde, Torgunn; Gravdehaug, Berit; Suhrke, Pål; Sánchez, E.; Bublevic, J.; Røe, Oluf Dimitri; Geitvik, Gry; Halset, Eline Holli; Rypdal, Maria Christine; Langerød, Anita; Lømo, Jon; Garred, Øystein; Porojnicu, Alina Carmen; Engebraaten, O.; Geisler, Jürgen; Lyngra, Marianne; Hansen, M. H.; Søiland, Håvard; Nakken, T.; Asphaug, Lars; Kristensen, Vessela N.; Sørlie, Therese; Sørlie, T.; Nygård, Jan Franz; Kiserud, Cecilie E.; Reinertsen, Kristin Valborg; Russnes, Hege Elisabeth Giercksky; Naume, Bjørn (Journal article; Peer reviewed, 2024)

    • Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series 

      Yule, Michael S.; Thompson, Joshua; Leesahatsawat, Khachonphat; Sousa, Mariana S.; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Dajani, Olav; Fallon, Marie; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; McDonald, James; McGovern, Josh; Roeland, Eric J.; Sayers, Judith; Skipworth, Richard J.E.; Ottestad, Inger; Philips, Iain; Simpson, Melanie Rae; Solheim, Tora S; Vagnildhaug, Ola Magne; McMillan, Donald; Laird, Barry J; Dolan, Ross D. (Journal article; Peer reviewed, 2024)
      Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement ...

    • Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s Disease 

      Knudtzon, Stephanie; Nordengen, Kaja; Grøntvedt, Gøril Rolfseng; Jarholm, Jonas Alexander; Eliassen, Ingvild Vøllo; Selnes, Per; Pålhaugen, Lene; Espenes, Johan Jacob; Gisladottir, Berglind; Waterloo, Knut K; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Peer reviewed, 2024)
      Cerebrospinal fluid total-tau (t-tau) and neurofilament light chain (NfL) are biomarkers of neurodegeneration and are increased in Alzheimer’s disease (AD). In order to adjust for age-related increases in t-tau and NfL, ...

    • Home-based postnatal care following early hospital discharge: a descriptive study of the Midwife Home care programme 

      Skarsgaard, Benedikte Kjetland; Henriksen, Therese Harvold; Dahlberg, Unn; Løvvik, Tone Shetelig; Aune, Ingvild (Journal article; Peer reviewed, 2024)
      Objective At St. Olav’s University Hospital in Trondheim, Norway, “Midwife Home” (MH) is an integrated home-based postnatal service for mothers who want early discharge (i.e. 6–24 h) after giving birth. The purpose of our ...

    • Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series 

      Brown, Leo R.; Sousa, Mariana S.; Yule, Michael S.; Baracos, Vickie E.; McMillan, Donald C.; Arends, Jann; Balstad, Trude Rakel; Bye, Asta; Dajani, Olav; Dolan, Ross D.; Fallon, Marie T.; Greil, Christine; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Maddocks, Matthew; McDonald, James; Ottestad, Inger; Phillips, Iain; Sayers, Judith; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Solheim, Tora S; Laird, Barry J; Skipworth, Richard J.E. (Journal article; Peer reviewed, 2024)
      Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or secondary endpoints. To date, there has been no review of the most ...

    • General practitioners retiring or relocating and its association with healthcare use and mortality: a cohort study using Norwegian national data 

      Vinjerui, Kristin Hestmann; Asheim, Andreas; Anthun, Kjartan Sarheim; Carlsen, Fredrik; Mjølstad, Bente Prytz; Nilsen, Sara Marie; Pape, Kristine; Bjørngaard, Johan Håkon (Journal article; Peer reviewed, 2024)

    • Long-term cardiac effects of modern treatment for Hodgkin’s lymphoma 

      Bjerring, Anders W.; Smeland, Knut Bjøro; Stokke, Thomas Muri; Haugaa, Kristina Ingrid Helena Hermann; Holte, Espen; Rösner, Assami; Kiserud, Cecilie E.; Edvardsen, Thor; Sarvari, Sebastian (Journal article; Peer reviewed, 2024)
      Background Hodgkin’s lymphoma (HL) is a hematological malignancy that affects both children and young adults. Traditional treatment is associated with a life-time prevalence of cardiac disease exceeding 50%. In the late ...

    • Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series 

      Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Coats, Andrew J.S.; Dajani, Olav; Dolan, Ross D.; Fallon, Marie T.; Greil, Christine; Grzyb, Alexandra; Kaasa, Stein; Koteng, Lisa Heide; May, Anne M.; McDonald, James; Ottestad, Inger; Philips, Iain; Roeland, Eric J.; Sayers, Judith; Simpson, Melanie Rae; Skipworth, Richard J.E.; Solheim, Tora S; Sousa, Mariana S.; Vagnildhaug, Ola Magne; Laird, Barry J.A. (Journal article; Peer reviewed, 2024)
      The use of patient-reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self-report on health, functioning, wellbeing, and perceptions of care, represent important measures of efficacy. ...

    • Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis—an explorative cross-sectional study 

      Cetrelli, Lena Elisabet; Lundestad, Anette; Gil, Elisabeth Grut; Fischer, Johannes Maria; Halbig, Josefine Mareile; Frid, Paula Hanna Therese; Angenete, Oskar W; Rosén, Annika; Tylleskär, Karin Birgitta; Luukko, Keijo; Nordal, Ellen Berit; Åstrøm, Anne-Kristine N; Skeie, Marit Slåttelid; Stunes, Astrid Kamilla; Bletsa, Athanasia; Sen, Abhijit; Feuerherm, Astrid Jullumstrø; Rygg, Marite (Journal article; Peer reviewed, 2024)
      Background Biomarkers may be useful in monitoring disease activity in juvenile idiopathic arthritis (JIA). With new treatment options and treatment goals in JIA, there is an urgent need for more sensitive and responsive ...

    • Disease activity trajectories from childhood to adulthood in the population-based Nordic juvenile idiopathic arthritis cohort 

      Rypdal, Veronika Gjertsen; Glerup, Mia; Rypdal, Martin Wibe; Arnstad, Ellen Dalen; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Myrup, Charlotte; Peltoniemi, Suvi; Rygg, Marite; Nordal, Ellen Berit (Journal article; Peer reviewed, 2024)
      Objectives To identify long-term disease activity trajectories from childhood to adulthood by using the clinical Juvenile Arthritis Disease Activity Score (cJADAS10) in juvenile idiopathic arthritis (JIA). Second, to ...

    • Evaluation of the nurse-assisted eHealth intervention ‘eHealth@Hospital-2-Home’ on self-care by patients with heart failure and colorectal cancer post-hospital discharge : protocol for a randomised controlled trial 

      Storm, Marianne; Morken, Ingvild Margreta; Austin, Rosalynn; Nordfonn, Oda Karin; Wathne, Hege Bjøkne; Urstad, Kristin Hjorthaug; Karlsen, Bjørg; Dalen, Ingvild; Gjeilo, Kari Hanne; Richardson, Alison; Elwyn, Glyn; Bru, Lars Edvin; Søreide, Jon Arne; Kørner, Hartwig; Moan, Rune; Strömberg, Anna; Lurås, Hilde; Husebø, Anne Marie Lunde (Journal article; Peer reviewed, 2024)
      Background: Patients with heart failure (HF) and colorectal cancer (CRC) are prone to comorbidity, a high rate of readmission, and complex healthcare needs. Self-care for people with HF and CRC after hospitalisation can ...

    • First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial 

      Ree, Anne Hansen; Saltyte Benth, Jurate; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Johansen, Christin; Negård, Anne; Bjørnetrø, Tonje; Nilsen, Hilde; Berg, Jens Petter; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)
      Background We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods Patients were ...

    • Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series 

      Vagnildhaug, Ola Magne; Balstad, Trude Rakel; Ottestad, Inger; Bye, Asta; Greil, Christine; Arends, Jann; Baracos, Vickie; Brown, Leo R.; Dajani, Olav; Dolan, Ross D.; Fallon, Marie; Fraser, Eilidh; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Kaasa, Stein; McDonald, James; Philips, Iain; Sayers, Judith; Simpson, Melanie Rae; Sousa, Mariana S.; Skipworth, Richard J.E.; Laird, Barry J.A.; Solheim, Tora S (Journal article; Peer reviewed, 2024)
      There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and ...

    • Exploring variation in timely reperfusion treatment in ST-segment elevation myocardial infarction in Norway: A national register-based cohort study 

      Uleberg, Bård Erling; Bønaa, Kaare Harald; Govatsmark, Ragna Elise Støre; Olsen, Frank; Jacobsen, Bjarne K.; Stensland, Eva; Hauglann, Beate Kristin; Vonen, Barthold Gisle; Førde, Olav Helge (Journal article; Peer reviewed, 2024)
      Objectives This study aimed to investigate determinants of reperfusion within recommended time limits (timely reperfusion) for ST-segment elevation myocardial infarction patients, exploring the impact of geography, patient ...

    • School children’s mental health during the COVID-19 pandemic 

      Martinsen, Kristin; Lisøy, Carina; Wentzel-Larsen, Tore; Neumer, Simon-Peter; Rasmussen, Lene-Mari Potulski; Adolfsen, Frode; Sund, Anne Mari; Ingul, Jo Magne (Peer reviewed; Journal article, 2024)
      Introduction: The COVID-19 pandemic significantly impacted the daily routines of children, with social distancing and quarantine leading to reduced social interactions and potential increased conflicts within families. ...

    • Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease 

      Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind; Pålhaugen, Lene; Hemminghyth, Mathilde Suhr; Jarholm, Jonas Alexander; Skogseth, Ragnhild Eide; Bråthen, Geir; Grøndtvedt, Gøril; Bjørnerud, Atle; Tecelao, Sandra; Waterloo, Knut; Aarsland, Dag; Fernández-Lebrero, Aida; García-Escobar, Greta; Navalpotro-Gómez, Irene; Turton, Michael; Hesthamar, Agnes; Kac, Przemyslaw R.; Nilsson, Johanna; Luchsinger, Jose; Hayden, Kathleen M.; Harrison, Peter; Puig-Pijoan, Albert; Zetterberg, Henrik; Hughes, Timothy M.; Suárez-Calvet, Marc; Karikari, Thomas K.; Fladby, Tormod; Blennow, Kaj (Journal article; Peer reviewed, 2024)
      Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates ...

    • Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis 

      Novy, Camilla; Busk, Øyvind; Tysnes, Ole-Bjørn; Landa, Sigve Strand; Aanjesen, Tori Navestad; Alstadhaug, Karl Bjørnar; Bjerknes, Tale Litlere; Bjørnå, Ingrid Kristine; Bråthen, Geir; Dahl, Elin; Demic, Natasha; Fahlström, Maria; Flemmen, Heidi Øyen; Hallerstig, Erika Carina; HogenEsch, Ineke; Kampman, Margitta; Kleveland, Grethe; Kvernmo, Helene Ballo; Ljøstad, Unn; Maniaol, Angelina; Morsund, Aase Hagen; Nakken, Ola; Olsen, Cathrine Goberg; Schlüter, Katrin Ruth; Utvik, May-Sissel; Yaseen, Ryaz; Holla, Øystein Lunde; Holmøy, Trygve; Høyer, Helle (Journal article; Peer reviewed, 2024)
      Genetic repeat expansions cause neuronal degeneration in amyotrophic lateral sclerosis as well as other neurodegenerative disorders such as spinocerebellar ataxia, Huntington’s disease and Kennedy’s disease. Repeat expansions ...

    • The association between age and long-term quality of life after curative treatment for prostate cancer: a cross-sectional study 

      Sletten, Reidun; Christiansen, Ola B.; Oldervoll, Line Merethe; Åstrøm, Lennart; Skjellegrind, Håvard Kjesbu; Saltyte Benth, Jurate; Kirkevold, Øyvind; Bergh, Sverre; Grønberg, Bjørn Henning; Rostoft, Siri; Bye, Asta; Mork, Paul Jarle; Slaaen, Marit (Journal article; Peer reviewed, 2024)
      Objective: We aimed to investigate the associations between age at radical prostate cancer treatment and long-term global quality of life (QoL), physical function (PF), and treatment-related side effects. Material and ...