St. Olavs hospital: Recent submissions

Now showing items 81-100 of 2447

    • Serum Concentrations of Selected Poly- and Perfluoroalkyl Substances (PFASs) in Pregnant Women and Associations with Birth Outcomes. A Cross-Sectional Study from Southern Malawi 

      Mwapasa, Mphatso; Huber, Sandra; Chakhame, Bertha Immaculate; Maluwa, Alfred; Odland, Maria Lisa; Röllin, Halina; Choko, Augustine; Xu, Shanshan; Odland, Jon Øyvind (Journal article; Peer reviewed, 2023)
      Pervasive exposure to per-and polyfluoroalkyl substances (PFASs) shows associations with adverse pregnancy outcomes. The aim of the present study was to examine the determinants of different serum PFAS concentrations in ...

    • Facilitators and barriers to hypertension management in urban Nepal: Findings from a qualitative study 

      Bhattarai, Sanju; Bajracharya, Swornim; Shrestha, Archana; Skovlund, Eva; Åsvold, Bjørn Olav; Mjølstad, Bente Prytz; Sen, Abhijit (Peer reviewed; Journal article, 2023)
      Introduction In Nepal, one-fourth of the adult population has hypertension. Despite provision of comprehensive hypertension services through the primary healthcare system, huge gaps in treatment and control of hypertension ...

    • Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer 

      Yndestad, Synnøve; Engebrethsen, Christina; Herencia-Ropero, A.; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun Kristine; Minsaas, Laura; Leirvaag, Beryl; Iversen, Gjertrud Titlestad; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Aase, Hildegunn Siv; Aas, Turid; Gudlaugsson, Einar; Llop-Guevara, Alba; Serra, Violeta; Janssen, Emiel; Lønning, Per Eystein; Knappskog, Stian; Eikesdal, Hans Petter (Peer reviewed; Journal article, 2023)
      Purpose Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to ...

    • Multifactorial assessment of Parkinson’s disease course and outcomes using trajectory modeling in a multiethnic, multisite cohort – extension of the LONG-PD study 

      Chase, Bruce A.; Krueger, Rejko; Pavelka, Lukas; Chung, Sun Ju; Aasly, Jan; Dardiotis, Efthimios; Premkumar, Ashvini P.; Schoneburg, Bernadette; Kartha, Ninith; Aunaetitrakul, Navamon; Frigerio, Roberta; Maraganore, Demetrius; Markopoulou, Katerina (Peer reviewed; Journal article, 2023)
      Background: The severity, progression, and outcomes of motor and non-motor symptoms in Parkinson’s disease (PD) are quite variable. Following PD cohorts holds promise for identifying predictors of disease severity and ...

    • Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study 

      Howe, Laurence J; Rasheed, Humaira; Jones, Paul Remy; Boomsma, Dorret I; Evans, David M; Giannelis, Alexandros; Hayward, Caroline; Hopper, John L; Hughes, Amanda; Lahtinen, Hannu; Li, Shuai; Lind, Penelope A; Martin, Nicholas G; Martikainen, Pekka; Medland, Sarah E; Morris, Tim T; Nivard, Michel G; Pingault, Jean-Baptiste; Silventoinen, Karri; Smith, Jennifer A; Willoughby, Emily A; Wilson, James F; Ahlskog, Rafael; Andreassen, Ole; Ask, Helga; Campbell, Archie; Cheesman, Rosa Catherine Gillespie; Cho, Yoonsu; Christensen, Kaare; Corfield, Elizabeth Claire; Dahm, Christina C.; Havdahl, Alexandra; Hill, William D; Kerr, Shona M; Nygaard, Marianne Rodriguez; Palviainen, Teemu; Pedersen, Nancy L; Plomin, Robert; Southey, Melissa C; Stoltenberg, Camilla; Åsvold, Bjørn Olav; Næss, Øyvind Erik; Davey Smith, George; Kaprio, Jaakko; Brumpton, Ben Michael; Davies, Neil Martin (Peer reviewed; Journal article, 2023)
      Background Previous Mendelian randomization (MR) studies using population samples (population MR) have provided evidence for beneficial effects of educational attainment on health outcomes in adulthood. However, estimates ...

    • Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament 

      Yang, Yang; Pullisaar, Helen; Stunes, Astrid Kamilla; Parreiras Nogueira, Liebert; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2023)
      Objectives Positive effects of irisin on osteogenic differentiation of periodontal ligament (PDL) cells have been identified previously, this study aims to examine its effect on orthodontic tooth movement (OTM) in ...

    • Variation in antibiotic consumption in very preterm infants-a 10 year population-based study 

      Huncikova, Zuzana; Stensvold, Hans Jørgen; Øymar, Knut Asbjørn Alexander; Vatne, Anlaug; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Moster, Dag; Eriksen, Beate Horsberg; Selberg, Terje Reidar; Rønnestad, Arild Erland; Klingenberg, Claus (Peer reviewed; Journal article, 2023)
      Objectives Wide variations in antibiotic use in very preterm infants have been reported across centres despite similar rates of infection. We describe 10 year trends in use of antibiotics and regional variations among ...

    • The central role of gastrin in gastric cancer 

      Waldum, Helge; Mjønes, Patricia Gjertrud (Peer reviewed; Journal article, 2023)
      The prevalence of gastric cancer has markedly declined, but due to the high mortality rates associated with gastric cancer, it is still a serious disease. The preferred classification of gastric cancer is according to ...

    • Symptoms and prevalence of common mental disorders in a heterogenous outpatient sample: an investigation of clinical characteristics and latent subgroups 

      Brattmyr, Lars Martin; Lindberg, Martin Schevik; Lundqvist, Jakob Samuel; Solem, Stian; Hjemdal, Odin; Anyan, Frederick; Havnen, Audun (Peer reviewed; Journal article, 2023)
      Background Patient-reported outcome measures (PROM) provide clinicians with information about patients’ perceptions of distress. When linked with treatment and diagnostic registers, new information on common mental ...

    • Breakthrough and Episodic Cancer Pain from a Palliative Care Perspective 

      Løhre, Erik Torbjørn; Jakobsen, Gunnhild; Solheim, Tora Skeidsvoll; Klepstad, Pål; Thronæs, Morten (Peer reviewed; Journal article, 2023)
      Cancer pain intensity (PI) fluctuates, but the relationship between pain flares and background pain with respect to pain management is not settled. We studied how flare and background PIs corresponded with treatment results ...

    • Violent Offending in Males With or Without Schizophrenia: A Role for Social Cognition? 

      Vaskinn, Anja; Rokicki, Jaroslav; Bell, Christina; Tesli, Natalia; Bang, Nina; Hjell, Gabriela; Fischer-Vieler, Thomas; Haukvik, Unn Kristin Hansen; Friestad, Christine (Peer reviewed; Journal article, 2023)
      Abstract Background and Hypothesis Reduced social cognition has been reported in individuals who have committed interpersonal violence. It is unclear if individuals with schizophrenia and a history of violence have larger ...

    • Psykiske lidelser og plager ved vedvarende opioidbruk for langvarige ikke-kreftrelaterte smerter – en registerstudie 

      Odsbu, Ingvild; Hjellvik, Vidar; Handal, Marte; Hamina, Aleksi; Clausen, Thomas; Lid, Torgeir Gilje; Borchgrevink, Petter Christian; Skurtveit, Svetlana Ondrasova (Peer reviewed; Journal article, 2024)
      Bakgrunn Kunnskap om psykiske lidelser blant pasienter med vedvarende opioidbruk for behandling av langvarige ikke-kreftrelaterte smerter er viktig, da psykiske lidelser og plager kan bidra til å forsterke eller ...

    • Systematic review: predictive value of organoids in colorectal cancer 

      Sakshaug, Baard Cristoffer; Folkesson, Emma Evelina; Haukaas, Tonje Husby; Visnes, Torkild; Flobak, Åsmund (Peer reviewed; Journal article, 2023)
      While chemotherapy alone or in combination with radiotherapy and surgery are important modalities in the treatment of colorectal cancer, their widespread use is not paired with an abundance of diagnostic tools to match ...

    • Nytt verktøy for tolkning av farmakogenetiske analyser 

      Tuv, Silja Skogstad; Spigset, Olav; Jensen, Elena; Vethe, Nils Tore; Nordal, Kristin (Peer reviewed; Journal article, 2023)
      Utilgjengelig kunnskap om tolkning av genvarianter som kan påvirke legemiddelrespons, er en barriere for implementering av farmakogenetikk. Vi har utviklet et nettbasert verktøy hvor man kan utføre spørringer og få ...

    • Nye sentre skal gi flere kliniske studier i Norge 

      Skoie, Inger Marie; Skogås, Jan Gunnar; Langø, Thomas; Myhr, Kjell-Morten; Myhre, Peder Langeland; Goll, Rasmus; Fretland, Signe Øien; Helland, Åslaug (Journal article; Peer reviewed, 2023)
      Seks NorTrials-sentre for behandlingsforskning er etablert ved universitetssykehusene. Målet er å øke antallet kliniske studier og forbedre pasientbehandlingen.

    • Frontoamygdala hyperconnectivity predicts affective dysregulation in adolescent moderate-severe TBI 

      Bickart, Kevin C.; Olsen, Alexander; Dennis, Emily L.; Babikian, Talin; Hoffman, Ann N.; Snyder, Aliyah; Sheridan, Christopher A.; Fischer, Jesse T.; Giza, Christopher C.; Choe, Meeryo C.; Asarnow, Robert F. (Peer reviewed; Journal article, 2022)
      In survivors of moderate to severe traumatic brain injury (msTBI), affective disruptions often remain underdetected and undertreated, in part due to poor understanding of the underlying neural mechanisms. We hypothesized ...

    • Automatic measurements of left ventricular volumes and ejection fraction by artificial intelligence: clinical validation in real time and large databases 

      Olaisen, Sindre Hellum; Smistad, Erik; Espeland, Torvald; Hu, Jieyu; Pasdeloup, David Francis Pierre; Østvik, Andreas; Aakhus, Svend; Rösner, Assami; Malm, Siri; Stylidis, Michael; Holte, Espen; Grenne, Bjørnar Leangen; Løvstakken, Lasse; Dalen, Håvard (Peer reviewed; Journal article, 2023)
      Aims Echocardiography is a cornerstone in cardiac imaging, and left ventricular (LV) ejection fraction (EF) is a key parameter for patient management. Recent advances in artificial intelligence (AI) have enabled fully ...

    • Return to work after surgery for degenerative cervical myelopathy: a nationwide registry-based observational study 

      Lønne, Vetle Vangen; Hara, Sozaburo; Gulati, Sasha; Aasdahl, Lene; Salvesen, Øyvind Olav; Nygaard, Øystein Petter; Solberg, Tore; Hara, Karen Walseth (Peer reviewed; Journal article, 2023)
      Background Few studies of high quality exist on return to work (RTW) rate after surgery for degenerative cervical myelopathy (DCM). This study aims to examine the RTW rate in patients undergoing surgery for DCM. Method ...

    • A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings 

      Foell, Dirk; Saers, Melanie; Park, Carolin; Brix, Ninna; Glerup, Mia; Kessel, Christoph; Wittkowski, Helmut; Hinze, Claas; Berntson, Lillemor; Fasth, Anders; Myrup, Charlotte; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels; Holzinger, Dirk; Niederberger, Christian; Schlüter, Bernhard (Peer reviewed; Journal article, 2023)
      Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We ...

    • Risk factors for SARS-CoV-2 infection: a test-negative case-control study with additional population controls in Norway 

      Sarjomaa, Marjut Anneli; Zhang, Chi; Tveten, Yngvar; Kersten, Hege; Reiso, Harald; Eikeland, Randi; Kongerud, Johny; Berg, Kristine Karlsrud; Thilesen, Carina; Nordbø, Svein Arne; Aaberge, Ingeborg Sundsvalen; Vandenbroucke, Jan; Pearce, Neil; Fell, Anne Kristin M. (Peer reviewed; Journal article, 2024)
      Objectives This study aims to assess risk factors for SARS-CoV-2 infection by combined design; first comparing positive cases to negative controls as determined by PCR testing and then comparing these two groups to an ...