St. Olavs hospital: Nye registreringer

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    • Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain 

      Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Miguel dos Santos, Rodrigo; Ryan, Liv; Skender, Belma; Bianco Nascimento Moreira, Jose; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Scrimgeour, Nathan Robert; Rafiee Tari, Atefe (Peer reviewed; Journal article, 2023)
      Background Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be partly mediated by blood-borne factors. ...

    • Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study 

      Zeldovich, Marina; Bockhop, Fabian; Covic, Amra; Mueller, Isabelle; Polinder, Suzanne; Mikolic, Ana; van der Vlegel, Marjolein; von Steinbuechel, Nicole; Åkerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzó, Pál; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emaliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Cooper, Jamie D.; Correia, Marta; Čović, Amra; Curry, Nicola; Czeiter, Endre; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Vik, Anne (Peer reviewed; Journal article, 2023)
      Background Comparison of patient-reported outcomes in multilingual studies requires evidence of the equivalence of translated versions of the questionnaires. The present study examines the factorial validity and comparability ...

    • Cognitive behavior therapy for adult eating disorders in routine clinical care: A systematic review and meta-analysis 

      Öst, Lars Gøran; Brattmyr, Lars Martin; Finnes, Anna; Ghaderi, Ata; Havnen, Audun; Hedman-Lagerlöf, Maria; Parling, Thomas; Welch, Elisabeth; Wergeland, Gro Janne Henningsen (Peer reviewed; Journal article, 2023)

    • Medial Temporal Lobe Atrophy in Predementia Alzheimer's Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort 

      Jarholm, Jonas Alexander; Bjørnerud, Atle; Dalaker, Turi Olene; Akhavi, Mehdi Sadat; Kirsebom, Bjørn-Eivind; Pålhaugen, Lene; Nordengen, Kaja; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Kalheim, Lisa Flem; Almdahl, Ina Selseth; Teceläo, Sandra Raquel Ramos; Fladby, Tormod; Selnes, Per (Peer reviewed; Journal article, 2023)
      Background: Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer’s disease (AD) and can be measured by segmentation of magnetic resonance images (MRI). Objective: To assess the clinical ...

    • Acceptance and use of a clinical decision support system in musculoskeletal pain disorders – the SupportPrim project 

      Granviken, Fredrik; Meisingset, Ingebrigt; Vasseljen, Ottar; Bach, Kerstin; Bones, Anita Formo; Klevanger, Nina Elisabeth (Journal article; Peer reviewed, 2023)
      Background We have developed a clinical decision support system (CDSS) based on methods from artificial intelligence to support physiotherapists and patients in the decision-making process of managing musculoskeletal (MSK) ...

    • Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival from Sepsis 

      Lawler, Patrick R.; Manvelian, Garen; Coppi, Alida; Damask, Amy; Cantor, Michael N.; Ferreira, Manuel A. R.; Paulding, Charles; Banerjee, Nilanjana; Li, Dadong; Jorgensen, Susan; Attre, Richa; Carey, David J.; Krebs, Kristine; Milani, Lili; Hveem, Kristian; Damås, Jan Kristian; Solligård, Erik; Stender, Stefan; Tybjærg-Hansen, Anne; Nordestgaard, Børge G.; Hernandez-Beeftink, Tamara; Rogne, Tormod; Flores Perez, Carlos Antonio; Villar, Jesús; Walley, Keith R.; Liu, Vincent X.; Fohner, Alison E.; Lotta, Luca A.; Kyratsous, Christos A.; Sleeman, Mark W.; Scemama, Michel; Delgizzi, Richard; Pordy, Robert; Horowitz, Julie E.; Baras, Aris; Martin, Greg S.; Steg, Philippe Gabriel; Schwartz, Gregory G.; Szarek, Michael; Goodman, Shaun G. (Peer reviewed; Journal article, 2023)
      OBJECTIVES: Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early ...

    • Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study 

      Klevjer, Marie; Rasheed, Humaira; Romundstad, Pål Richard; Madssen, Erik; Brumpton, Ben Michael; Bye, Anja (Peer reviewed; Journal article, 2023)
      Aims A low resting heart rate (RHR) implies a more efficient heart function and a lower risk of cardiovascular disease. However, observational studies have reported a U-shaped association between RHR and atrial fibrillation ...

    • Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections 

      Dyrhovden, Ruben; Eagan, Tomas Mikal Lind; Fløtten, Øystein; Siljan, William Ward; Leegaard, Truls Michael; Bø, Bjørnar; Fardal, Hilde; Grøvan, Fredrik; Kildahl-Andersen, Arne; Larssen, Kjersti Wik; Tilseth, Rune; Hjetland, Reidar; Løes, Sigbjørn Suk; Lindemark, Frode; Tellevik, Marit Gjerde; Breistein, Rebecca Irene; Kommedal, Øyvind (Peer reviewed; Journal article, 2023)
      Background - Many community-acquired pleural infections are caused by facultative and anaerobic bacteria from the human oral microbiota. The epidemiology, clinical characteristics, pathogenesis, and etiology of such ...

    • Initial management and survival of patients with primary metastatic bladder cancer before the immunotherapy era: a population-based study from Norway 

      Møller, Christina Tanem; Tafjord, Gunnar; Blindheim, Augun Jodis; Berge, Viktor; Fosså, Sophie Dorothea; Kulle, Bettina (Peer reviewed; Journal article, 2023)
      Before immunotherapy became part of the management of metastatic bladder cancer (mBC), systemic anti-cancer treatment comprised primarily of platinum-based chemotherapy. The objective of this study was to describe the ...

    • Randomised, placebo-controlled, double-blinded trial of fecal microbiota transplantation in severe obesity: a study protocol 

      Valle, Per Christian; Skjevling, Linn; Johnsen, Peter Holger; Almå, Kristin Helen; Kulseng, Bård Eirik; Goll, Rasmus; Hanssen, Hege Marie; Fjellstad, Maria Serafia (Peer reviewed; Journal article, 2023)
      Introduction - Obesity is one of the main threats to public health in western countries and increases the risk of several diseases, overall morbidity and mortality. Sustained weight loss will reduce risk factors and improve ...

    • Physical activity behavior and its association with global cognitive function three months after stroke: The Nor-COAST study. 

      Luzum, Geske; Gunnes, Mari; Lydersen, Stian; Saltvedt, Ingvild Tina; Thingstad, Anne Pernille Mæhle; Thrane, Gyrd; Askim, Torunn (Peer reviewed; Journal article, 2023)
      Objective - The purposes of this study were to determine the association between physical activity (PA) behavior and global cognitive function 3 months after stroke and to explore the role of physical capacity as a mediating ...

    • Mortality and subsequent healthcare use among older patients discharged to a municipality with excess demand for elderly care 

      Bjørnelv, Gudrun Maria Waaler; Asheim, Andreas; Nilsen, Sara Marie; Anthun, Kjartan Sarheim; Carlsen, Fredrik; Aam, Stina; Kimbell, Elizabeth Anna; Bjørngaard, Johan Håkon (Peer reviewed; Journal article, 2023)
      There is limited knowledge on how excess demand for elderly care influences patient outcomes. We used a natural experiment to estimate the causal effect of discharging elderly patients from hospital to municipalities with ...

    • Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management 

      Blom, Kjersti Benedicte; Kro, Grete Anette Birkeland; Midtvedt, Karsten; Jenssen, Trond; Reisæter, Anna Varberg; Rollag, Halvor; Hartmann, Anders; Sagedal, Solbjørg; Sjaastad, Ivar; Tylden, Garth Daryl; Njølstad, Gro; Nilsen, Einar; Christensen, Andreas; Åsberg, Anders; Birkeland, Jon Arne (Peer reviewed; Journal article, 2023)
      Background. Following kidney transplantation (KT), cytomegalovirus (CMV) infection remains an important challenge. Both prophylactic and preemptive antiviral protocols are used for CMV high-risk kidney recipients (donor ...

    • Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group 

      Hanssen, Henner; Moholdt, Trine; Bahls, Martin; Biffi, Alessandro; Siegrist, Monika; Lewandowski, Adam J.; Biondi-Zoccai, Giuseppe; Cavarretta, Elena; Kokkvoll, Ane Sofie; Løchen, Maja-Lisa; Maestrini, Viviana; Pinto, Rita Salvador; Palermi, Stefano; Thivel, David; Wojcik, Malgorzata; Hansen, Dominique; Van Craenenbroeck, Emeline M.; Weghuber, Daniel; Kraenkel, Nicolle; Tiberi, Monica (Peer reviewed; Journal article, 2023)
      There is an immediate need to optimize cardiovascular (CV) risk management and primary prevention of childhood obesity to timely and more effectively combat the health hazard and socioeconomic burden of CV disease from ...

    • Serum Concentrations of Selected Poly- and Perfluoroalkyl Substances (PFASs) in Pregnant Women and Associations with Birth Outcomes. A Cross-Sectional Study from Southern Malawi 

      Mwapasa, Mphatso; Huber, Sandra; Chakhame, Bertha Immaculate; Maluwa, Alfred; Odland, Maria Lisa; Röllin, Halina; Choko, Augustine; Xu, Shanshan; Odland, Jon Øyvind (Journal article; Peer reviewed, 2023)
      Pervasive exposure to per-and polyfluoroalkyl substances (PFASs) shows associations with adverse pregnancy outcomes. The aim of the present study was to examine the determinants of different serum PFAS concentrations in ...

    • Facilitators and barriers to hypertension management in urban Nepal: Findings from a qualitative study 

      Bhattarai, Sanju; Bajracharya, Swornim; Shrestha, Archana; Skovlund, Eva; Åsvold, Bjørn Olav; Mjølstad, Bente Prytz; Sen, Abhijit (Peer reviewed; Journal article, 2023)
      Introduction In Nepal, one-fourth of the adult population has hypertension. Despite provision of comprehensive hypertension services through the primary healthcare system, huge gaps in treatment and control of hypertension ...

    • Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer 

      Yndestad, Synnøve; Engebrethsen, Christina; Herencia-Ropero, A.; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun Kristine; Minsaas, Laura; Leirvaag, Beryl; Iversen, Gjertrud Titlestad; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Aase, Hildegunn Siv; Aas, Turid; Gudlaugsson, Einar; Llop-Guevara, Alba; Serra, Violeta; Janssen, Emiel; Lønning, Per Eystein; Knappskog, Stian; Eikesdal, Hans Petter (Peer reviewed; Journal article, 2023)
      Purpose Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to ...

    • Multifactorial assessment of Parkinson’s disease course and outcomes using trajectory modeling in a multiethnic, multisite cohort – extension of the LONG-PD study 

      Chase, Bruce A.; Krueger, Rejko; Pavelka, Lukas; Chung, Sun Ju; Aasly, Jan; Dardiotis, Efthimios; Premkumar, Ashvini P.; Schoneburg, Bernadette; Kartha, Ninith; Aunaetitrakul, Navamon; Frigerio, Roberta; Maraganore, Demetrius; Markopoulou, Katerina (Peer reviewed; Journal article, 2023)
      Background: The severity, progression, and outcomes of motor and non-motor symptoms in Parkinson’s disease (PD) are quite variable. Following PD cohorts holds promise for identifying predictors of disease severity and ...

    • Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study 

      Howe, Laurence J; Rasheed, Humaira; Jones, Paul Remy; Boomsma, Dorret I; Evans, David M; Giannelis, Alexandros; Hayward, Caroline; Hopper, John L; Hughes, Amanda; Lahtinen, Hannu; Li, Shuai; Lind, Penelope A; Martin, Nicholas G; Martikainen, Pekka; Medland, Sarah E; Morris, Tim T; Nivard, Michel G; Pingault, Jean-Baptiste; Silventoinen, Karri; Smith, Jennifer A; Willoughby, Emily A; Wilson, James F; Ahlskog, Rafael; Andreassen, Ole; Ask, Helga; Campbell, Archie; Cheesman, Rosa Catherine Gillespie; Cho, Yoonsu; Christensen, Kaare; Corfield, Elizabeth Claire; Dahm, Christina C.; Havdahl, Alexandra; Hill, William D; Kerr, Shona M; Nygaard, Marianne Rodriguez; Palviainen, Teemu; Pedersen, Nancy L; Plomin, Robert; Southey, Melissa C; Stoltenberg, Camilla; Åsvold, Bjørn Olav; Næss, Øyvind Erik; Davey Smith, George; Kaprio, Jaakko; Brumpton, Ben Michael; Davies, Neil Martin (Peer reviewed; Journal article, 2023)
      Background Previous Mendelian randomization (MR) studies using population samples (population MR) have provided evidence for beneficial effects of educational attainment on health outcomes in adulthood. However, estimates ...

    • Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament 

      Yang, Yang; Pullisaar, Helen; Stunes, Astrid Kamilla; Parreiras Nogueira, Liebert; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2023)
      Objectives Positive effects of irisin on osteogenic differentiation of periodontal ligament (PDL) cells have been identified previously, this study aims to examine its effect on orthodontic tooth movement (OTM) in ...