• Development of national curriculum guidelines using a modified RAND/UCLA appropriateness method 

  Hill, Sophie; Rusaw, David F.; Goihl, Tobias; Hjerman, Anne Katrine; Bolstad Schwanborg, Linn; Bauge, Krister (Peer reviewed; Journal article, 2020)

  In 2017, the Norwegian Ministry of Education and Research implemented a project to develop curriculum guidelines for all health and social care programmes. The modified RAND/UCLA appropriateness method used by the group ...

• Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo 

  Ræder, Synnøve Brandt; Sandbakken, Erik Thorvaldsen; Nepal, Anala; Løseth, Kirsti; Bergh, Kåre; Witsø, Eivind; Otterlei, Marit (Peer reviewed; Journal article, 2021)

  Antimicrobial resistance is an increasing threat to global health and challenges the way we treat infections. Peptides containing the PCNA interacting motif APIM (APIM-peptides) were recently shown to bind to the bacterial ...

• Express Team-Based Learning (eTBL): A Time-Efficient TBL Approach in Neuroradiology 

  Smeby, Susanne Skjervold; Lillebo, Børge; Slørdahl, Tobias Schmidt; Berntsen, Erik Magnus (Peer reviewed; Journal article, 2019)

  Rationale and Objectives Team-based learning (TBL) is a student-centred, teacher-directed instructional method that promotes active learning. The application phase of TBL stimulates group discussion and critical thinking, ...

• The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection 

  Daussy, Coralie F.; Monard, Sarah C.; Guy, Coralie; Muñoz-González, Sara; Chazal, Maxime; Anthonsen, Marit Walbye; Jouvenet, Nolwenn; Henry, Thomas; Dreux, Marlène; Meurs, Eliane F.; Hansen, Marianne Dore (Peer reviewed; Journal article, 2021)

  Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ...

• Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations 

  Boer, Cindy G.; Hatzikotoulas, Konstantinos; Southam, Lorraine; Stefánsdóttir, Lilja; Almeida, Rodrigo Coutinho de; Zhang, Yanfei; Wu, Tian T.; Zheng, Jie; Hartley, April; Teder-Laving, Maris; Skogholt, Anne Heidi; Terao, Chikashi; Zengini, Eleni; Alexiadis, George; Barysenka, Andrei; Bjornsdottir, Gyda; Gabrielsen, Maiken Elvestad; Gilly, Arthur; Ingvarsson, Thorvaldur; Johnsen, Marianne Bakke; Jonsson, Helgi; Kloppenburg, Margreet; Luetge, Almut; Lund, Sigrun H; Magi, Reedik; Mangino, Massimo; Nelissen, Rob G.H.H.; Shivakumar, Manu; Steinberg, Julia; Takuwa, Hiroshi; Thomas, Laurent; Tuerlings, Margo; Babis, George C.; Cheung, Jason Pui Yin; Kang, Jae Hee; Kraft, Peter; Lietman, Steven A.; Samartzis, Dino; Slagboom, P. Eline; Stefansson, Kari; Thorsteinsdottir, Unnur; Tobias, Jonathan H.; Uitterlinden, André G.; Winsvold, Bendik K S; Zwart, John Anker Henrik; Smith, George Davey; Sham, Pak Chung; Thorleifsson, Gudmar; Hveem, Kristian; Zeggini, Eleftheria (Peer reviewed; Journal article, 2021)

  Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated ...

• Visuopathy of prematurity: is retinopathy just the tip of the iceberg? 

  Ingvaldsen, Sigrid Hegna; Morken, Tora Sund; Austeng, Dordi; Dammann, Olaf (Peer reviewed; Journal article, 2021)

  Background: Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular disease burden found ...

• Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study 

  van Wijk, Roel P J; van Dijck, Jeroen T. J. M.; Timmers, Marjolein; van Veen, Ernest; Citerio, Giuseppe; Lingsma, Hester F; Maas, Andrew I. R.; Menon, David K; Peul, Wilco C.; Stocchetti, Nino; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)

  Purpose: Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national ...

• Surgical Complications in Postchemotherapy Retroperitoneal Lymph Node Dissection for Nonseminoma Germ Cell Tumour: A Population-based Study from the Swedish Norwegian Testicular Cancer Group 

  Gerdtsson, Axel; Håkansson, Ulf; Törnblom, Magnus; Jancke, George; Negaard, Helene Francisca Stigter; Glimelius, Ingrid; Halvorsen, Dag; Karlsdottir, Åsa; Haugnes, Hege Sagstuen; Andreassen, Kristine Engen; Larsen, Signe Melsen; Holmberg, Göran; Wahlqvist, Rolf; Tandstad, Torgrim; Cohn-Cedermark, Gabriella; Ståhl, Olof; Kjellmann, Anders (Journal article, 2020)

  Background Reports on perioperative complications after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for nonseminoma germ cell tumour (NSGCT) are from experienced single centres, with a lack of ...

• Randomized phase III trial comparing switch-maintenance pemetrexed with observation followed by pemetrexed at progression in advanced NSCLC 

  Halvorsen, Tarje Onsøien; Stokke, Kristin; Killingberg, Kristin Toftaker; Raj, Sunil Xavier; Sørhaug, Sveinung; Brustugun, Odd Terje; Fløtten, Øystein; Helbekkmo, Nina; Hornslien, Kjersti; Madebo, Tesfaye; Fluge, Sverre; Grønberg, Bjørn Henning (Peer reviewed; Journal article, 2020)

  Objectives: Two phase III trials show that maintenance pemetrexed therapy after platinum-doublet chemotherapy prolongs overall survival (OS) and progression free survival (PFS) in advanced non-squamous non-small-cell lung ...

• Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving 

  Monnoyer, Roxane; Eftedal, Ingrid; Hjelde, Astrid; Deb, Sanjoy Kumar; Haugum, Kjersti; Lautridou, Jacky (Peer reviewed; Journal article, 2021)

  Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ...

• Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia 

  Klevmoen, Marianne; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Svilaas, Tone; Vesterbekkmo, Elisabeth Kleivhaug; Hovland, Anders; Berge, Christ; van Lennep, Jeanine Roeters; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2021)

  Background and aims Women with heterozygous familial hypercholesterolemia (FH) are recommended to initiate statin treatment at the same age as men (from 8 to 10 years of age). However, statins are contraindicated when ...

• Olfactory hallucinations in a population-based sample 

  Wehling, Eike Ines; Bless, Josef J; Hirnstein, Marco; Kråkvik, Bodil; Vedul-Kjelsås, Einar; Hugdahl, Kenneth; Kalhovde, Anne Martha; Larøi, Frank (Peer reviewed; Journal article, 2021)

  Olfactory hallucinations referring to olfactory perceptions in the absence of chemical stimuli, occur in non-clinical and clinical populations. Few studies have investigated their prevalence in the general population and ...

• Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk 

  Olsen, Erik; Holzhauer, Björn; Julius, Stevo; Kjeldsen, Sverre; Larstorp, Anne Cecilie Kjeldsen; Mancia, Giuseppe; Mehlum, Maria Hollund; Mo, Rune; Rostrup, Morten; Søraas, Camilla Lund; Zappe, Dion H.; Weber, Michael A. (Peer reviewed; Journal article, 2021)

  Purpose Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to <130/80 mmHg in middle-aged and elderly hypertensive patients with diabetes ...

• Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients 

  Grønseth, Stine; Rogne, Tormod; Hannula, Raisa; Åsvold, Bjørn Olav; Afset, Jan Egil; Damås, Jan Kristian (Peer reviewed; Journal article, 2021)

  Pneumocystis jirovecii is a threat to iatrogenically immunosuppressed individuals, a heterogeneous population at rapid growth. We assessed the ability of an in-house semiquantitative real-time PCR assay to discriminate ...

• Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding 

  Bjørk, Marte-Helene; Kristoffersen, Espen Saxhaug; Tronvik, Erling Andreas; Nordeng, Hedvig Marie Egeland (Peer reviewed; Journal article, 2021)

  Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ...

• Colorectal cancer patients’ experiences with supervised exercise during adjuvant chemotherapy—A qualitative study 

  Hatlevoll, Ingunn; Skolbekken, John-Arne; Oldervoll, Line Merethe; Wibe, Arne; Hofsli, Eva (Peer reviewed; Journal article, 2021)

  Background Colorectal cancer (CRC) is a common cancer worldwide, with increasing numbers surviving and living with long-term side effects from treatment. Physical exercise during or after treatment may have several beneficial ...

• How the Norwegian population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown 

  Mæland, Silje; Bjørknes, Ragnhild; Lehmann, Stine; Sandal, Gro Mjeldheim; Hazell, William; Rabben, Åsgeir Kjetland; Vedaa, Øystein; Skogen, Jens Christoffer; Fadnes, Lars T. (Journal article; Peer reviewed, 2021)

  Aims The aim of this study was to examine how the Norwegian general adult population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown. We assessed quarantine, symptoms, ...

• High neuroticism is associated with reduced negative affect following sleep deprivation 

  Saksvik-Lehouillier, Ingvild; Langvik, Eva; Saksvik, Simen Berg; Kallestad, Håvard; Follesø, Hanna Størksen; Austad, Sigrun Borgen; Dahlberg, Johanna; Ringen, Heidi; Tanum, Tiril Kristine; Sørengaard, Torhild Anita; Karlsen, Håvard Rudi; Smedbøl, Trine; Olsen, Alexander (Peer reviewed; Journal article, 2021)

  The aim was to investigate how neuroticism moderates the affective consequences of personalized mild-moderate partial sleep deprivation. A total of 52 healthy subjects aged 18–35 years completed the NEO PI-3 at baseline, ...

• Smac-mimetics reduce numbers and viability of human osteoclasts 

  Moen, Ingrid Nyhus; Westhrin, Marita; Håland, Erling; Haug, Markus; Nonstad, Unni; Klaharn, Merisa; Standal, Therese; Starheim, Kristian K. (Peer reviewed; Journal article, 2021)

  Elevated activity of bone-degrading osteoclasts (OC) contributes to pathological bone degradation in diseases such as multiple myeloma. Several proinflammatory cytokines, including TNF, contribute to osteoclastogenesis. ...

• Stability and Change of the Personality Traits Languidity and Flexibility in a Sample of Nurses: A 7–8 Years Follow-Up Study 

  Pallesen, Ståle; Thun, Eirunn; Waage, Siri; Vedaa, Øystein; Harris, Anette Kristoffersen; Blytt, Kjersti Marie; Kaur, Puneet; Bjorvatn, Bjørn (Peer reviewed; Journal article, 2021)

  The traits languidity (tendency to become tired/sleepy upon losing sleep) and flexibility (ability to sleep and work at odd times) have been implicated in shift work tolerance. However, there is a dearth of knowledge about ...

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