Blar i Publikasjoner fra Cristin - St. Olavs hospital på tidsskrift "European Journal of Clinical Pharmacology"
Viser treff 1-1 av 1
-
Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction – a prospective observational study
(Peer reviewed; Journal article, 2020)Purpose The β-1 adrenergic receptor blocker metoprolol is primarily metabolized by the polymorphic enzyme cytochrome P 450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity. Our purpose was to investigate the ...