Blar i Publikasjoner fra Cristin - St. Olavs hospital på forfatter "Valla, Marit"
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The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study
Sandvei, Marie Søfteland; Opdahl, Signe; Valla, Marit; Lagiou, Pagona; Vesterfjell, Ellen Veronika; Rise, Tor Vikan; Overrein, Tina Syvertsen; Skjervold, Anette Hansen; Engstrøm, Monica J; Bofin, Anna M.; Vatten, Lars J. (Peer reviewed; Journal article, 2021)Background: Because birth size appears to be positively associated with breast cancer risk, we have studied whether this risk may differ according to molecular breast cancer subtypes. Methods: A cohort of 22,931 women born ... -
CCND1 amplification in breast cancer -associations with proliferation, histopathological grade, molecular subtype and prognosis
Valla, Marit; Klæstad, Elise; Ytterhus, Borgny; Bofin, Anna M. (Peer reviewed; Journal article, 2022)CCND1 is located on 11q13. Increased CCND1 copy number (CN) in breast cancer (BC) is associated with high histopathological grade, high proliferation, and Luminal B subtype. In this study of CCND1 in primary BCs and ... -
FastPathology: An open-source platform for deep learning-based research and decision support in digital pathology
Pedersen, André; Valla, Marit; Bofin, Anna Mary; Perez de Frutos, Javier; Reinertsen, Ingerid; Smistad, Erik (Peer reviewed; Journal article, 2021)Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, ... -
Long term trends of breast cancer incidence according to proliferation status
Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M. (Peer reviewed; Journal article, 2022)Background Long-term breast cancer incidence trends according to proliferation status are poorly described. We studied time-trends in breast cancer incidence, using mitotic count and Ki-67 as markers of proliferation. ... -
PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes
Skjervold, Anette Hansen; Valla, Marit; Ytterhus, Borgny; Bofin, Anna M. (Peer reviewed; Journal article, 2023)Introduction P21-activated kinase 1 (PAK1) is known to be overexpressed in several human tumour types, including breast cancer (BC). It is located on chromosome 11 (11q13.5-q14.1) and plays a significant role in proliferation ...