• Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits 

      Nayor, Matthew; Short, Meghan I.; Rasheed, Humaira; Lin, Honghuang; Jonasson, Christian; Yang, Qiong; Hveem, Kristian; Felix, Janine F.; Morrison, Alanna C.; Wild, Philipp S.; Morley, Michael P.; Cappola, Thomas P.; Benson, Mark D.; Ngo, Debby; Sinha, Sumita; Keyes, Michelle J.; Shen, Dongxiao; Wang, Thomas J.; Larson, Martin G.; Brumpton, Ben Michael; Gerszten, Robert E.; Omland, Torbjørn; Vasan, Ramachandran S. (Peer reviewed; Journal article, 2020)
      Abstract Background: We used a large-scale, high-throughput DNA aptamer-based discovery proteomic platform to identify circulating biomarkers of cardiac remodeling and incident heart failure (HF) in community-dwelling ...
    • Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy 

      Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Taraldsen, Maria Dalen; Gigante, Bruna; Follestad, Turid; Røsjø, Helge Rørvik; Omland, Torbjørn; Wiseth, Rune; Madssen, Erik; Bye, Anja (Peer reviewed; Journal article, 2023)
      Lipid-rich coronary atherosclerotic plaques often cause myocardial infarction (MI), and circulating biomarkers that reflect lipid content may predict risk of MI. We investigated the association between circulating microRNAs ...
    • Cardiac Dysfunction and Arrhythmias 3 Months After Hospitalization for COVID-19 

      Ingul, Charlotte Ingeborg Björk; Grimsmo, Jostein; Mecinaj, Albulena; Trebinjac, Divna; Nossen, Magnus Berger; Andrup, Simon; Grenne, Bjørnar; Dalen, Håvard; Einvik, Gunnar; Stavem, Knut; Follestad, Turid; Josefsen, Tony Andre; Omland, Torbjørn; Jensen, Torstein (Peer reviewed; Journal article, 2022)
      Background - The extent of cardiac dysfunction post‐COVID‐19 varies, and there is a lack of data on arrhythmic burden. Methods and Results - This was a combined multicenter prospective cohort study and cross‐sectional ...
    • Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study 

      Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord; Wisløff, Ulrik; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn; Røsjø, Helge (Peer reviewed; Journal article, 2021)
      Background MicroRNA (miR)-210 expression is induced by acute and chronic hypoxia and provides prognostic information in patients with aortic stenosis and acute coronary syndrome. We hypothesized that circulating miR-210 ...
    • Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. 

      Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid; Gigante, Bruna; Røsjø, Helge; Omland, Torbjørn; Langaas, Mette; Bye, Anja (Peer reviewed; Journal article, 2019)
      Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been ...
    • Patterns of Cardiac Troponin I Concentrations as Risk Predictors of Cardiovascular Disease and Death: The Trøndelag Health Study 

      Lyngbakken, Magnus Nakrem; Kimenai, Dorien M.; Hveem, Kristian; Dalen, Håvard; Røsjø, Helge Rørvik; Omland, Torbjørn (Peer reviewed; Journal article, 2023)
      Background Concentrations of cardiac troponin predict risk of cardiovascular disease and death in the general population. There is limited evidence on changing patterns of cardiac troponin in the years preceding cardiovascular ...
    • Rationale and design of the PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA II) trial: a randomized, placebo-controlled, multicenter trial 

      Mecinaj, Albulena; Gulati, Geeta; Heck, Siri Lagethon; Holte, Espen; Fagerland, Morten Wang; Larsen, Alf Inge; Blix, Egil Støre; Geisler, Jürgen; Wethal, Torgeir; Omland, Torbjørn (Journal article, 2021)
      Background Recent advances in the treatment algorithms of early breast cancer have markedly improved overall survival. However, anthracycline- and trastuzumab-associated cardiotoxicity may lead to dose-reduction or halt ...