Blar i Publikasjoner fra Cristin - St. Olavs hospital på forfatter "Neale, Benjamin M."
-
Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries
Surakka, Ida; Wu, Kuan-Han; Hornsby, Whitney; Wolford, Brooke N.; Shen, Fred; Zhou, Wei; Huffman, Jennifer E.; Pandit, Anita; Hu, Yao; Brumpton, Ben Michael; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Walters, Robin G.; Hveem, Kristian; Kooperberg, Charles; Zöllner, Sebastian; Wilson, Peter W.F.; Sutton, Nadia R.; Daly, Mark J.; Neale, Benjamin M.; Willer, Cristen J. (Peer reviewed; Journal article, 2023)Stroke is the second leading cause of death and disability worldwide. Stroke prevalence varies by sex and ancestry, possibly due to genetic heterogeneity between subgroups. We performed a genome-wide meta-analysis of 16 ... -
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases
Zhao, Huiling; Rasheed, Humaria; Nøst, Therese Haugdahl; Cho, Yoonsu; Liu, Yi; Bhatta, Laxmi; Bhattacharya, Arjun; Hemani, Gibran; Davey Smith, George; Brumpton, Ben Michael; Zhou, Wei; Neale, Benjamin M.; Gaunt, Tom R.; Zheng, Jie (Peer reviewed; Journal article, 2022)Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on ...