Browsing Publikasjoner fra Cristin - St. Olavs hospital by Journals "Communications Biology"
Now showing items 1-3 of 3
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A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
(Journal article; Peer reviewed, 2024)Trace elements are important for human health but may exert toxic or adverse effects. Mechanisms of uptake, distribution, metabolism, and excretion are partly under genetic control but have not yet been extensively mapped. ... -
Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT
(Peer reviewed; Journal article, 2022)Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron-related ... -
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
(Peer reviewed; Journal article, 2021)Oxidative DNA damage in the brain has been implicated in neurodegeneration and cognitive decline. DNA glycosylases initiate base excision repair (BER), the main pathway for oxidative DNA base lesion repair. NEIL1 and NEIL3 ...